Clinical trials: Etiology
ARDS Due to Disease Caused by SARS Co-V-2
Prediction of Conversion From Vv-ECMO to Va-ECMO in COVID-19 Patients
In December 2019, cases of a novel lung disease, later referred to as COVID-19, were first reported in China. The virus SARS-CoV-2 was identified as the causative agent.
- Trial name
- ECMOPred-vvva (NCT05910996)
- Testing
- Conversion from vv-ECMO to va-ECMO
- Where
- Austria
- Volunteers
- 99 people
- Sponsor
- Kepler University Hospital
Vascular Infection Caused by C. Burnetii
Vascular Infections Caused by Coxiella Burnetii
high morbidity and mortality. In France, Coxiella burnetii-related vascular infections appear to be increasing, though data remain limited.
- Trial name
- COXIVAS (NCT07305402)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Bordeaux
Mood Disorders, Depression
Hormonal Causes of Menstrual-Related Mood Disorders
This study will explore possible hormonal causes of menstrual-related mood disorders (MRMD) by stopping the menstrual cycle with a drug called Lupron and then giving in sequence two menstrual cycle hormones, progesterone and…
- Trial name
- NCT00100360
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Spinal Cord Neoplasm
FDG PET-MRI for the Diagnosis of Spinal Cord Lesions
To compare the results and understand the possible benefits from FDG-PET/MRI during different scanning time points after FDG, a type of contrast drug, is given.
- Trial name
- NCT04219969
- Testing
- Fludeoxyglucose F-18, Magnetic Resonance Imaging, Positron Emission Tomography
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- M.D. Anderson Cancer Center
Liver Cirrhosis
A Phase 2 Study of Foscenvivint in Liver Cirrhosis Patients Caused by HIV/HCV Co-infection With Hemophilia
This is a phase 2 study to evaluate the efficacy and safety of foscenvivint in patients with liver cirrhosis resulting from HIV/HCV co-infection in the setting of hemophilia.
- Trial name
- OP-724-H202 (NCT07681089)
- Testing
- Foscenvivint
- Where
- 4 sites in Japan
- Volunteers
- 7 people
- Sponsor
- Kiminori Kimura, MD
Anal Cancer, Carcinoma of the Appendix
Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal Cancer
RATIONALE: Palonosetron hydrochloride may prevent nausea and vomiting caused by radiation therapy. It is not yet known whether palonosetron hydrochloride is more effective than a placebo in preventing nausea and vomiting.
- Conditions
- Anal Cancer, Carcinoma of the Appendix, Colorectal Cancer, Extrahepatic Bile Duct Cancer
- Trial name
- NCT00903396
- Testing
- palonosetron hydrochloride
- Where
- 69 sites in United States
- Volunteers
- 7 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Allergy
Efficacy and Safety Study Of Short Ragweed Pollen Sublingual-Oral Immunotherapy
The primary objective of this study is to demonstrate that SLIT administered pre-and co-seasonally is effective in reducing rhinoconjunctivitis symptoms during the entire short ragweed pollen season.
- Trial name
- NCT01353079
- Testing
- Short Ragweed Pollen Allergenic Extract
- Where
- United States
- Volunteers
- 429 people
- Sponsor
- Greer Laboratories
Resuscitation
The Effect of Fatigue on CPR
Background: This study, in contrast to the previous studies, generated a scenario of fatigue in an earthquake scenario and aimed to measure the effect of fatigue on the quality of cardiopulmonary resuscitation (CPR) performed by…
- Trial name
- NCT06280118
- Testing
- Fatigue
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Artvin Coruh University
Methylmalonic Acidemia (MMA)
A Prospective Study of Pediatric Participants up to 16 Years of Age With Methylmalonic Acidemia (MMA) Due to Mutations in the MMUT Gene
Methylmalonic Acidemia (MMA) is a severe and rare condition that affects how the body turns food into energy. In people with MMA, the body is missing or has a very low activity of a specific protein (an enzyme called…
- Trial name
- NCT07432880
- Where
- 8 sites in United States, Italy and 2 more
- Volunteers
- 30 people
- Sponsor
- Genespire Srl
Delirium, Delirium Drug-Induced
Estimation of Delirium Data Completeness
Currently physicians and nurses rely on their own clinical skills and experience to diagnose and record 'delirium' in the Electronic Health Records (EHR).
- Conditions
- Delirium, Delirium Drug-Induced, Delirium Confusional State, Delirium, Cause Unknown
- Trial name
- NCT04084821
- Testing
- none - observation only
- Where
- Israel
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- Efficacy Care R&D Ltd
Onychomycosis Due to Trichophyton Rubrum, Onychomycosis Due to Trichophyton Mentagrophytes
Early Feasibility Study to Evaluate the Efficacy and Safety of the RenewalNail™ Plasma Treatment System in Patients With Mild to Moderate Onychomycosis (Fungal Nail)
Early feasibility study to determine if a three-treatment protocol with the RenewalNail™ plasma treatment system over a week will result in mycological cure and/or clear nail growth on the treated hallux toe.
- Trial name
- NCT03072550
- Testing
- RenewalNail™ Plasma Treatment System
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- DeviceFarm, Inc.
Severe Acute Cholangitis
ERCP Versus PTBD for Severe Acute Cholangitis Caused by Bile Duct Stones
This study is a prospective, randomized controlled trial designed to compare the effectiveness and safety of endoscopic retrograde cholangiopancreatography (ERCP) with percutaneous transhepatic biliary drainage (PTBD) for the…
- Trial name
- NCT07064980
- Testing
- Endoscopic Retrograde Cholangiopancreatography, Percutaneous Transhepatic Biliary Drainage
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Wuhan Integrated Traditional Chinese and Western Medicine Hospital
Ischemic Stroke
Administration of CBG000592 (Riboflavin/Vitamin B2) in Patients With Acute Ischemic Stroke
Administration of CBG000592 (riboflavin/vitamin B2) in patients with acute ischemic stroke to know if it causes a reduction of glutamate-mediated excitotoxicity.
- Trial name
- NCT02446977
- Testing
- Vitamin B2 Streuli®, Solution for injection
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Castillo, José, M.D.
Carbapenem-Resistant Enterobacteriaceae Infection
Impact of Ceftazidime / Avibactam Treatment vs Better Available Therapy on Mortality of Patients With Infections Caused by Carbapenem-resistant Enterobacteria
Patients with infections caused by carbapenem-resistant enterobacteria treated with CAZ-AVI versus patients treated with BAT are compared. The BAT group includes fosfomycin, tigecycline, gentamicin, meropenem and colistin.
- Trial name
- CAVICOR (NCT04167228)
- Testing
- Ceftazidime-Avibactam, Best Available Therapy
- Where
- 17 sites in Spain
- Volunteers
- 348 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Diabetic Peripheral Neuropathy
Treatment for Foot Pain Caused by Diabetic Neuropathy Using Recurrent TransCutaneous Magnetic Stimulation (TCMS)
The study will evaluate whether an experimental medical device that emits a series of brief, intense magnetic pulse will relieve foot pain from Diabetic Neuropathy (DN) if used weekly for a month
- Trial name
- NCT04000867
- Testing
- Transcutaneous Magnetic Stimulation (TCMS)
- Volunteers
- 20 people
- Sponsor
- ZyGood LLC
Sexually Transmitted Diseases, Bacterial, Bacterial Urinary Tract Infection
UROGEN WELL D-ONE : Evaluation of a Novel Diagnostic for Sexually Transmitted Bacterial Infections
UROGEN WELL D-ONE Principal research question: Can the UROGEN WELL D-ONE assay detect urinary tract infections and urethritis in clinical samples from patients attending Genitourinary Medicine outpatient clinics as accurately as…
- Conditions
- Sexually Transmitted Diseases, Bacterial, Bacterial Urinary Tract Infection, Antimicrobial Resistance
- Trial name
- NCT04182230
- Testing
- No intervention. This study was an evalution with no intervention.
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- Cwm Taf University Health Board (NHS)
Glaucoma, Neovascular
Study to Learn How the Drug Aflibercept Works in in Japanese Patients With Increased Eye Pressure That is Caused by New Blood Vessels Growing in the Eye (Neovascular Glaucoma or NVG). Safety of the Drug and Patients' Tolerability of the Drug Injection is Also Studied
The researchers in this trial want to learn how the drug aflibercept works in in Japanese patients with increased eye pressure that is caused by new blood vessels growing in the eye (neovascular glaucoma or NVG).
- Trial name
- VENERA (NCT03639675)
- Testing
- Aflibercept (EYLEA, BAY86-5321), Topical IOP-lowering drugs
- Where
- 7 sites in Japan
- Volunteers
- 16 people
- Sponsor
- Bayer
Onychomycosis of Toenail
Pilot Study of Swift Microwave Device for Onychomycosis
This is an open, single site, pilot study in Canadian subjects diagnosed with mild to moderate toenail onychomycosis caused by dermatophytes.
- Trial name
- NCT05674747
- Testing
- Swift Microwave treatment - weekly x 4wks, Swift Microwave treatment - Every other week x 4wks, Swift Microwave treatment - Every other week x 24wks
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- Mediprobe Research Inc.
Improve Quality of Life, Heavy Menstrual Bleeding
Treatment of Heavy and/or Prolonged Menstrual Bleeding Without Organic Cause
Abnormal uterine bleeding encompasses abnormalities in the regularity, duration of flow, frequency, and/or blood flow volume relative to normal menstruation.
- Trial name
- NCT02943655
- Testing
- combined contraceptive pills (microcept), medroxyprogesterone acetate (progest), mefenamic acid (ponstan forte)
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- Assiut University
Lung Cancer, Surgery
The Cardiac Stress and Electrocardiographic Changes Caused by Lung Cancer Surgery
Lung cancer surgery causes significant changes in the small circulation as well as changes in the intrathoracic anatomy. The effects of lung cancer surgery on electrocardiography and the cardiac stress associated with the…
- Conditions
- Lung Cancer, Surgery, Arrhythmia, Myocardial Ischemia
- Trial name
- NCT05094843
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Tampere University Hospital
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