Clinical trials: Etiology
Primary Ovarian Insufficiency, Premature Menopause
Causes and Consequences of Primary Ovarian Insufficiency
100 women with primary ovarian insufficiency will be included for extensive diagnostic workup to improve diagnostic precision by extended autoantibody screening and genetic and toxicological testing.
- Trial name
- Clinical POI (NCT04082169)
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Chronic Heart Failure
Left Atrial Distensibility Guiding Management in Advanced Chronic Heart Failure
Background and Purpose- According to our prior studies, left atrial (LA) distensibility was associated significantly with left ventricular filling pressure in patients with acute myocardial infarction (AMI), chronic stable…
- Trial name
- NCT01307722
- Testing
- left atrial distensibility-guiding prescription of heart failure drugs
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Connective Tissue Diseases, Blood Coagulation Disorders
CLUE Study: Connective Tissue Disease Leg Ulcer Etiology Study
To explore the hypothesis that leg ulcers are associated with hypercoagulable states, the CLUE study will evaluate patients with connective tissue disease associated leg ulcers, to identify risk factors (especially…
- Conditions
- Connective Tissue Diseases, Blood Coagulation Disorders, Leg Ulcers, Rheumatoid Arthritis
- Trial name
- CLUE (NCT00522002)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- George Washington University
Pregnancy Anemia
Prevalence Study of the Etiology of Pregnancy Anemia
Anemia during pregnancy occurs in 41% of women. The most common etiology is iron deficiency, but studies to determine prevalence of other causes of anemia in pregnancy are still lacking.
- Trial name
- PREGAN (NCT03448432)
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University Hospital, Brest
Chronic Wounds, Venous Leg Ulcers (VLUs)
Efficacy of Carbonlife Amniotic Tissue Product in the Treatment of Chronic Wounds
Chronic wounds constitute a significant global health burden, affecting millions of individuals and contributing to increased morbidity, diminished quality of life, and rising healthcare costs.
- Conditions
- Chronic Wounds, Venous Leg Ulcers (VLUs), Diabetic Foot Ulcers (DFUs), Arterial Ulcers
- Trial name
- NCT07223892
- Testing
- Amniotic Tissue Allograft
- Volunteers
- 600 people
- Sponsor
- Bardia Anvar
Malignant Biliary Obstruction
Clinical Trial of Bile Etiology ,Proteomics and Metabonomics of Malignant Biliary Obstruction
To investigate bile culture and susceptibility test in patients with malignant biliary obstruction (MBO) or relation between bile, portal vein or vein culture and biliary infection.
- Trial name
- MBO-IR (NCT01073514)
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Endocarditis Infective, Endocarditis, Bacterial
Dalbavancin Therapy for Infective Endocarditis
This study compares two treatment strategies for antibiotic therapy in endocarditis. The aim of the study is to determine which treatment is more effective overall and better tolerated by patients.
- Trial name
- EndoDalba (NCT07699211)
- Testing
- Dalbavancin administration, Standard of Care (Investigator Choice)
- Where
- 9 sites in Germany
- Volunteers
- 184 people
- Sponsor
- Stefan Hagel
Lysosomal Storage Disease
The Classification and Cause of Leukodystrophies of Unknown Cause
Leukodystrophy is a disease of the white matter of the brain. White matter is the portion of the brain responsible for conducting electrical impulses from one area of the brain to the other.
- Trial name
- NCT00001671
- Where
- 5 sites in United States, France and 2 more
- Volunteers
- 400 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Chronic Myeloproliferative Disorders, Fatigue
American Ginseng in Treating Patients With Fatigue Caused by Cancer
RATIONALE: American ginseng may reduce fatigue in patients with cancer. It is not yet known whether American ginseng is more effective than a placebo in treating cancer-related fatigue.
- Conditions
- Chronic Myeloproliferative Disorders, Fatigue, Leukemia, Lymphoma
- Trial name
- NCT00719563
- Testing
- American ginseng
- Where
- 326 sites in United States
- Volunteers
- 364 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Epilepsy
This Study Will Assess the Etiology, Potential Risk Factors, and Seizure Types in Patients Over 50 With Epileptic Seizure Disorder, Using Laboratory Tests, EEG, and Neuroimaging Findings.
This study underscores the importance of studying the etiology, clinical characteristics, and types of epilepsy in the elderly to improve diagnosis and management in our community.
- Trial name
- NCT07026409
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Lymphedema, Secondary, Lymphedema of Leg
Secondary Lymphedema Due to Human Adjuvant Disease
This observational, descriptive, retrospective study the clinical and imaging findings of 10 lower legs of 5 patients with previous history of injection of modeling substances for cosmetic purposes at buttocks and hips ande…
- Conditions
- Lymphedema, Secondary, Lymphedema of Leg, Granuloma, Foreign-Body
- Trial name
- NCT04588493
- Testing
- Lower extremity Lymphoscintigraphy
- Where
- Mexico
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Hospital Angeles del Pedregal
Hepatopulmonary Syndrome
Investigation of the Prevalence of Hepatopulmonary Syndrome in Cirrhosis Patients Caused by Hepatitis B in Western China
to investigate the prevalence of hepatopulmonary syndrome in cirrhosis patients caused by Hepatitis B in western China
- Trial name
- NCT03435406
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Southwest Hospital, China
Acinetobacter Baumannii-calcoaceticus Complex, Hospital-acquired Bacterial Pneumonia
Study to Evaluate the Efficacy and Safety of Intravenous Sulbactam-ETX2514 in the Treatment of Patients With Infections Caused by Acinetobacter Baumannii-calcoaceticus Complex
This is a 2-part study, with Part A being the randomized, controlled portion of the study in patients with ABC hospital-acquired bacterial pneumonia (HABP), ventilator-associated bacterial pneumonia (VABP), or bacteremia.
- Conditions
- Acinetobacter Baumannii-calcoaceticus Complex, Hospital-acquired Bacterial Pneumonia, Ventilator-associated Bacterial Pneumonia, Bacteremia
- Trial name
- ATTACK (NCT03894046)
- Testing
- Sulbactam, Durlobactam, Colistin
- Where
- 90 sites in United States, Belarus and 15 more
- Volunteers
- 207 people
- Sponsor
- Entasis Therapeutics
Alcoholism
Naltrexone for Relapse Prevention
This study is to evaluate the safety and effectiveness of an injectable slow releasing preparation of naltrexone to reduce alcohol consumption and risk of relapse in alcohol-dependent subjects.
- Trial name
- NCT00000442
- Testing
- naltrexone (Revia)
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- UConn Health
Diarrhea, Secretory
Parasitic Causes of Secretory Diarrhea in Children and Chronically Ill Adult.
Diarrhea is one of the most common reasons for people to seek medical advice - but it can range from being a mild, temporary condition, to be life threading condition.
- Trial name
- NCT03166670
- Testing
- stool examination, real time polymerase chain reaction
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Oophorectomy for Benign Reasons, Hysterectomy
Benign Reproductive Tissue Analysis for Endometrial Cancer Markers
Background: Endometrial cancer (cancer of the lining of the uterus) is the most common gynecologic cancer in the United States. Currently, there are no markers (components of blood and tissue that determine who might be at risk…
- Trial name
- NCT00481754
- Where
- United States
- Volunteers
- 359 people
- Sponsor
- National Cancer Institute (NCI)
Autoimmunity, Inguinal Hernia
ASIA-Mesh: a Pilot Study for Diagnostics and Treatment on ASIA Syndrome Caused by Polypropylene Mesh Implantation
In the present pilot study, a possible relation between the implantation of PP mesh for inguinal hernia, vaginal prolapse and SUI repair and subsequent systemic auto-immune complaints is investigated by testing immunologic and…
- Conditions
- Autoimmunity, Inguinal Hernia, Stress Urinary Incontinence, Pelvic Organ Prolapse
- Trial name
- NCT06363903
- Testing
- mesh allergy test, blood tests, Mesh removal
- Where
- 3 sites in Netherlands
- Volunteers
- 50 people
- Sponsor
- Maxima Medical Center
Inflammatory Disease
Study of the Proteome and Cytokines During Inflammatory Syndromes of Different Etiologies.
The hypotheses of our research are based on the fact that various pathological states, infection, cancer, inflammatory disease, can induce an inflammatory syndrome, through different pathways, even though the clinical…
- Trial name
- Proteome (NCT01903642)
- Testing
- proteomic analysis
- Where
- France
- Volunteers
- 97 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Allergy
Safety of ALK Ragweed Tablet
This trial is performed to assess whether ALK Ragweed Tablet is safe to use in adults
- Trial name
- NCT00330083
- Testing
- ALK Ragweed Tablet
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- ALK-Abelló A/S
Leishmaniasis, Visceral
A Study Evaluating Sitamaquine Compared With Amphotericin B In The Treatment Of Visceral Leishmaniasis.
Sitamaquine is an 8-aminoquinoline which is being developed as an oral treatment for visceral leishmaniasis (VL). Pre-clinical and subsequent clinical investigations have demonstrated oral efficacy against Leishmania donovani.
- Trial name
- NCT00381394
- Testing
- sitamaquine
- Where
- 3 sites in India
- Volunteers
- 61 people
- Sponsor
- GlaxoSmithKline
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