Clinical trials: Etomidate
Choledocholithiasis, Cholangiocarcinoma
Etomidate vs. Midazolam for Sedation During ERCP
Recently up-coming drug, etomidate which is a modulator of GABA(gamma-Aminobutyric acid)-A receptor has been known that it maintains the appropriate sedative levels and affects little effects on respiratory system.
- Conditions
- Choledocholithiasis, Cholangiocarcinoma, Pancreatitis, Pancreatic Cancer
- Trial name
- NCT02027311
- Testing
- Etomidate, Midazolam, Meperidine
- Where
- South Korea
- Volunteers
- 63 people
- Sponsor
- Cheju Halla General Hospital
Intubation Complication
Evaluating the Hemodynamic Effects of Ketamine Versus Etomidate During Rapid Sequence Intubation
The purpose of this study is to compare the hemodynamic effects of ketamine v etomidate during rapid sequence intubation (RSI) in the pre-hospital and emergency department setting.
- Trial name
- Ket-RSI (NCT03545503)
- Testing
- Etomidate, Ketamine
- Where
- United States
- Volunteers
- 428 people
- Sponsor
- South East Area Health Education Center, Wilmington, NC
Acute Respiratory Failure
Randomized Trial of Sedative Choice for Intubation
Among critically ill adults undergoing emergency tracheal intubation, one in five experience hypotension, cardiac arrest, or death.
- Trial name
- RSI (NCT05277896)
- Testing
- Ketamine, Etomidate
- Where
- 6 sites in United States
- Volunteers
- 2,367 people
- Sponsor
- Vanderbilt University Medical Center
Adrenal Insufficiency
Evaluation of Etomidate on Adrenal Function in Trauma Patients
Trauma patients are at increased risk for adrenal function insufficiency. A commonly used agent for rapid sequence intubation (RSI) is known to decrease adrenal function.
- Trial name
- NCT00462644
- Testing
- RSI sedation with etomidate/succinylcholine, RSI sedation with fentanyl/midazolam/succinylcholine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Tennessee
Cardiopulmonary Arrest, Respiratory Arrest
Etomidate Versus Ketamine for Emergency Endotracheal Intubation: a Prospective Randomized Clinical Trial
Patients who are having problems breathing sometimes require placement of a breathing tube in their mouth and windpipe. The purpose of this breathing tube is to save the patient's life.
- Trial name
- EvK (NCT02643381)
- Testing
- Etomidate, Ketamine, Emergency Endotracheal Intubation
- Where
- United States
- Volunteers
- 801 people
- Sponsor
- University of Texas Southwestern Medical Center
Airway Control, Anesthesia
Ketamine Versus Etomidate for Rapid Sequence Intubation
The purpose of this study is to compare the effectiveness and safety of ketamine and etomidate during rapid sequence intubation (RSI).
- Conditions
- Airway Control, Anesthesia, Intubation, Complication
- Trial name
- NCT01823328
- Testing
- Ketamine, Etomidate
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Hennepin Healthcare Research Institute
Depression, Delirium
Cognitive Recovery After Electroconvulsive Therapy and General Anesthesia
This study is geared toward characterizing the recovery of brain activity and cognitive function following treatments of electroconvulsive therapy and ketamine general anesthesia.
- Conditions
- Depression, Delirium, Seizures, Cognitive Disorders
- Trial name
- RCC2 (NCT02761330)
- Testing
- Ketamine, Electroconvulsive Therapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Washington University School of Medicine
Critical Illness
Ketamine / Propofol Admixture "Ketofol" at Induction in the Critically Ill Against Etomidate: KEEP PACE Trial
The hypothesis of this study is that a Ketamine / Propofol mixture will produce more stable hemodynamics as compared to Etomidate during emergent intubations in the intensive care unit.
- Trial name
- KEEP PACE (NCT02105415)
- Testing
- Ketamine / Propofol Admixture, Etomidate
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Mayo Clinic
Surgery
Comparison of Etomidate Plus Propofol, Etomidate Alone on Induction of Anesthesia
Comparison of Etomidate plus Propofol vs. Propofol or Etomidate alone during induction of anesthesia.
- Trial name
- NCT03820388
- Testing
- Propofol 2mg/kg, Etomidate 0.3 mg/kg, Propofol 1 mg/kg
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Sepsis, Trauma
The Effect of Etomidate on Patient Outcomes After Single Bolus Doses
The primary aim is to determine the difference in hospital length of stay between septic patients given etomidate and those given midazolam for induction during rapid sequence intubation (RSI) in the emergency department.
- Trial name
- NCT00441792
- Testing
- Etomidate, midazolam
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Advocate Hospital System