Clinical trials: Etomidate, open to volunteers
Insomnia, Digestive Endoscopy
Changes in Etomidate Dosage in Patients With Insomnia Undergoing Intravenous Anesthesia
To compare the dosage requirement of etomidate under intravenous anesthesia between patients with insomnia and those with normal sleep pattern.
- Trial name
- NCT07028177
- Testing
- No interventions, it is a observational study
- Where
- China
- Volunteers
- 840 people
- Sponsor
- Beijing Tiantan Hospital
Etomidate, Esketamine
Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children
Objective: To explore the effect of etomidate and esketamine on postoperative pain after tonsillectomy in children. Methods: Investigators enrolled 64 children with American Society of Anesthesiologists (ASA) physical status I…
- Conditions
- Etomidate, Esketamine, Tonsillectomy, Children
- Trial name
- NCT07062601
- Testing
- Etomidate and fentanyl group, Etomidate and esketamine group
- Volunteers
- 64 people
- Sponsor
- Anqing Municipal Hospital
Post-Traumatic Stress Disorder, Acute Respiratory Failure
Effect of Ketamine and Etomidate During RSI on Long Term Outcomes
The RSI-LTO study collects long-term outcomes from the RSI trial (NCT05277896). One-third of adults who are intubated in the ED or ICU experience symptoms of posttraumatic stress disorder (PTSD).
- Trial name
- RSI-LTO (NCT06179485)
- Testing
- Ketamine, Etomidate
- Where
- 6 sites in United States
- Volunteers
- 1,756 people
- Sponsor
- Vanderbilt University Medical Center
Major Surgery
The GUARDIAN Trial - Induction Agent Sub-Study
This is a sub-study of the overall GUARDIAN trial (NCT04884802) in which some GUARDIAN trial participants will be additionally randomized to etomidate vs propofol for anesthetic induction.
- Trial name
- NCT04934683
- Testing
- Routine Blood Pressure Management, Tight Blood Pressure Management, Etomidate Induction
- Where
- 11 sites in United States, China and 2 more
- Volunteers
- 6,254 people
- Sponsor
- The University of Texas Health Science Center, Houston
Gastroscopy, Colonoscopy
A Clinical Trial to Evaluate the Efficacy and Safety of Methoxyethyl Etomidate Hydrochloride for Sedation/Anesthesia During Gastroscopy/Colonoscopy
A total of 270 subjects undergoing gastroscopy/colonoscopy were randomly assigned to the methoxetomidate hydrochloride group and the etomidate group according to the ratio of 2:1 with etomidate as the control group.Neither the…
- Trial name
- NCT06858852
- Testing
- ET-26HCl 0.8mg/kg group, Etomidate Injectable Product 0.3mg/kg group
- Where
- 6 sites in China
- Volunteers
- 270 people
- Sponsor
- Ahon Pharmaceutical Co., Ltd.
Etomidate Combined With Propofol, Hypertension
Safety of Etomidate-propofol Mixture vs. Propofol for Total Intravenous Anesthesia in Elderly Patients Undergoing Abdominal Surgery
The purpose of this study is to access the safety of etomidate - propofol mixture vs propofol for total intravenous anesthesia in elderly patients undergoing abdominal surgery.
- Trial name
- NCT07019246
- Testing
- EP mixture, Propofol
- Where
- China
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Gastrointestinal Endoscopy
Etomidate Combined With Propofol Versus Propofol for Sedation in High-Altitude Patients During Gastroscopy: a Randomized Multicenter Clinical Trial
One of the most common adverse events during sedated gastrointestinal endoscopy is hypoxemia, which can lead to serious consequences.
- Trial name
- NCT07079176
- Testing
- etomidate combined with propofol, propofol
- Volunteers
- 732 people
- Sponsor
- RenJi Hospital
Anesthesia, Propofol Adverse Reaction
Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)
The purpose of this study is to evaluate the hemodynamics and adverse event profile in comparison between two treatment arms, one using an admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7), and one using…
- Conditions
- Anesthesia, Propofol Adverse Reaction, Etomidate Adverse Reaction, Anesthesia Complication
- Trial name
- PEAC (NCT05358535)
- Testing
- Admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2), Admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Texas Southwestern Medical Center
Etomidate Use Disorder, Repetitive Transcranial Magnetic Stimulation (rTMS)
Repetitive Transcranial Magnetic Stimulation for People With Etomidate Addiction (SToP-E-rTMS x Etomidate)
The goal of this clinical trial is to learn if high-frequency rTMS works to treat etomidate addiction in adults. It will also learn about the safety and tolerability of rTMS.
- Trial name
- SToP-E (NCT07736742)
- Testing
- high-frequency Repetitive Transcranial Magnetic Stimulation, Repetitive transcranial magnetic stimulation
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong
Induction Anesthesia, Drug Interactions
Relationship Between Remimazolam and Etomidate in Induction of General Anesthesia
In modern anesthesia practice, anesthesiologists often need to choose a combination of multiple drugs according to the specific conditions and surgical needs of patients, which can not only achieve more fine anesthesia…
- Trial name
- NCT07012902
- Testing
- Etomidate, Remimazolam, Remimazolam-etomidate
- Where
- China
- Volunteers
- 125 people
- Sponsor
- Second Hospital of Shanxi Medical University
Hemodynamics
The Effect-site Concentration of Remifentanil Blunting Endotracheal Intubation Responses During Anesthesia Induction With Lidocaine or Sufentanil Combined With Etomidate: A Randomized Controlled Study
The aim of this study was to compare the effect-site target concentration (including EC₅₀ and EC₉₀) of remifentanil required to suppress cardiovascular responses to tracheal intubation during anesthesia induction with etomidate…
- Trial name
- NCT07089173
- Testing
- Intravenous normal saline (NS 0.9), intravenous sufentanil, Intravenous lidocaine
- Where
- China
- Volunteers
- 99 people
- Sponsor
- Peking University Shenzhen Hospital
Primary Aldosteronism
Subtyping Primary Aldosteronism With Para-chloro-2-[18F]Fluoroethyl-etomidate
The goal of this clinical trial is to investigate the uptake characteristics of [18F]CETO in adrenal tissue in patients with two different subtypes of primary aldosteronism.
- Trial name
- SPACE (NCT06616142)
- Testing
- [18F]CETO tracer, Dexamethasone oral, Adrenal vein sampling
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- University Medical Center Groningen