Clinical trials: Eustachian Tube Dysfunction
Eustachian Tube Dysfunction
The Accuracy of Tests of Eustachian Tube Function
The Eustachian tube links the middle ear to the back of the nose and is designed to open to allow the pressure in the air-filled middle ear to be equal to external (atmospheric) pressure.
- Trial name
- NCT02385175
- Testing
- Different objective clinical tests of Eustachian tube function, Different patient-completed questionnaires relating to Eustachian tube dysfunction
- Where
- United Kingdom
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Eustachian Tube Dysfunction
Gas Supply, Demand and Middle Ear Gas Balance -- Diagnosis of Eustachian Tube Dysfunction
The aim of this study is to determine which of the many Eustachian tube function tests (or combination of tests) is most helpful in finding out what is causing ear problems in children and adult patients with middle-ear diseases…
- Trial name
- NCT01974726
- Testing
- ET Stress test, Sonotubometry, Forced Response Test (FRT)
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Eustachian Tube Dysfunction, Hearing Disorders
FFP3 Respirators and Ears - Effects on Middle Ear Pressure and Hearing
This is Prospective Basic Science Study whose aims are as follows: 1. To determine the effect of Filtering Facepiece (FFP3M) respirators on eustachian tube function and hearing 2.
- Conditions
- Eustachian Tube Dysfunction, Hearing Disorders, Nasal Obstruction
- Trial name
- FFP3-RAE (NCT05222230)
- Testing
- FFP3 Mask
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Otic Barotrauma, Pressure Injury
Diagnostic Precision and Accuracy Using the Teed Scoring System Versus the O'Neill Grading System
This validation study investigates the diagnostic precision and accuracy when grading otic barotrauma using two alternative gradings systems including the TEED and the OGS grading systems.
- Conditions
- Otic Barotrauma, Pressure Injury, Ear Injury, Barotitis
- Trial name
- OGS (NCT04726306)
- Testing
- Otic Barotrauma Grading System
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Eustachian Tube Dysfunction, Facial Pain
SinuSonic for ETD and Facial Pain: Acoustic Vibration + Oscillating Expiratory Pressure
This study was originally designed with three aims: (1) healthy controls to assess nasal nitric oxide, (2) adults with Eustachian Tube Dysfunction (ETD), and (3) adults with facial pain/pressure.
- Trial name
- NCT04404036
- Testing
- SinuSonic Device
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Chronic Eustachian Salpingitis
Feasibility of Balloon Dilation of the Eustachian Tubes Under Local Anesthesia
The objective of this study is to demonstrate that balloon dilation of the Eustachian tubes can be done successfully for treatment of chronic dilatory Eustachian tube dysfunction under local anesthesia with acceptable patient…
- Trial name
- NCT04055714
- Testing
- Balloon dilation of the Eustachian tubes
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Piedmont Ear, Nose, Throat and Related Allergy, PC
Eustachian Tube Dysfunction
Eustachian Tube Dysfunction Assessment
The purpose of the study is to understand the exact mechanism of the activity of paratubal muscles in opening eustachian tube in patients with the functional eustachian tube and those with the eustachian tube dysfunction problem.
- Trial name
- ETDA (NCT02667301)
- Testing
- EMG recording, Tympanic Cavity Air Exchange Test, Tympanometer test
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Stratejik Yenilikci Girisimler Ltd.
Patulous Eustachian Tube Dysfunction
A Trial of Clay Weight on the Ear Drum for Patulous Eustachian Tube
The Eustachian tube is a tube that connects the back of the nose with the ear. Its job is to keep the pressure on the inside of the eardrum close to the pressure outside the eardrum, so that the eardrum can vibrate properly.
- Trial name
- NCT00933478
- Testing
- Clay
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Eustachian Tube Dysfunction, Middle Ear Disease
Ph.D.-Project: Eustachian Tube Dysfunction: Causes, Diagnosis, Treatment, and Prognosis
Background: The Eustachian Tube (ET) is a mucosa-lined connection between the nasopharynx and the middle ear cavity. It is believed to have three functions: 1) ventilation of and pressure equalization in the middle ear cavity, 2)…
- Conditions
- Eustachian Tube Dysfunction, Middle Ear Disease, Hearing Loss, Conductive, Middle Ear Problem
- Trial name
- NCT05055115
- Testing
- Balloon Eustachian Tuboplasty
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Regional Hospital West Jutland
Eustachian Tube Dysfunction, Sudden Hearing Loss
What is the Tympanic Membrane Healing Time After Insertion of a Gelfoam PE Tube?
Pilot study done to evaluate the breakdown and and potential utility of a bioabsorbable ventilation ear tube made with gelatin.
- Conditions
- Eustachian Tube Dysfunction, Sudden Hearing Loss, Meniere Disease
- Trial name
- NCT04902963
- Testing
- PE tube
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Skovlund Medical Products, LLC
Eustachian Tube Dysfunction
Pretympanoplasty Assessment of Patency and Mucociliary Function of Eustachian Tube
The eustachian tube (ET) performs three primary functions: pressure equalisation between the nasopharyms and middle ear: clearance of mucus from the middle ear, and prevention of sound or fluid reflux from the nasopharynx(1) .In…
- Trial name
- NCT05229380
- Testing
- Saccharin test
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Otitis Media With Effusion, Eustachian Tube Disorder
Novel Imaging of the Eustachian Tube; Patient Study
The purpose of the study is to establish wether a contrast medium applied to the middle ear can be used to diagnose pathology in the auditory tube.
- Trial name
- CT-ET (NCT02282540)
- Testing
- Iodixanol to the Eustachian tube
- Where
- Norway
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Eustachian Tube Dysfunction
Tubomanometry and EarPopper Devices for Eustachian Tube Function Testing
The Eustachian tube (ET) is a biological tube that links the middle ear to the back of the nose and throat. It has several functions, of which the most important is to maintain optimal middle-ear health.
- Trial name
- NCT03850197
- Testing
- EarPopper, Tympanometry, Tubomanometry
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cuneyt M. Alper
Hearing Loss, Noise-Induced, Eustachian Tube Dysfunction
Hearing/ET/Vestibular in Balloon Pilots
This study looks at whether working as a hot-air balloon pilot-being exposed to burner noise, changes in air pressure/temperature, and vertical acceleration-is linked to changes in hearing, Eustachian tube function, and…
- Conditions
- Hearing Loss, Noise-Induced, Eustachian Tube Dysfunction, Vestibular Disorders, Occupational Exposure
- Trial name
- FLIGHT-EAR (NCT07200310)
- Testing
- Non-invasive audiologic and vestibular assessments
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Eustachian Tube Dysfunction
Correlation Analysis Between ETF and Prognosis of Tympanoplasty
The regular opening of the eustachian tube plays an important role in maintaining normal pressure in middle ear cavity, hearing function and preventing the occurrence of middle ear inflammation.
- Trial name
- NCT03424369
- Testing
- Tympanoplasty
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Eustachian Tube Disorder
Evaluating Changes in Middle Ear Pressure Caused by CPAP
This study is an investigation into the effect that CPAP has on the pressure in the middle ear. It will evaluate the middle ear pressure and ear drum appearance at multiple levels of CPAP pressure delivered via a full face mask.
- Trial name
- NCT02882022
- Testing
- Continuous positive airway pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Virginia
Eustachian Tube Dysfunction
Effect of Novel Exhalational Delivery System With Fluticasone (EDS-FLU) on Eustachian Tube Dysfunction (ETD)
Intranasal nasal steroid sprays are the mainstay of treatment for chronic Eustachian tube dysfunction despite having little supportive evidence in the literature.
- Trial name
- NCT05275686
- Testing
- Fluticasone Propionate 93 MCG/1 ACTUATION Nasal Spray
- Where
- 4 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center