Clinical trials: Euthymic
Bipolar Disorder
The Effect of Intranasal Insulin on Neurocognitive Function in Euthymic Patients With Bipolar Disorder
It is hypothesized that the intranasal administration of insulin will enhance hippocampal-dependent neurocognitive performance in euthymic patients with bipolar I or II disorder.
- Trial name
- NCT00314314
- Testing
- Intranasal Insulin, Diluent
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Conditions Influencing Health Status, Bipolar Disorders
Functional Correlates of Bipolar Disorders and Effects of the Psychoeducation. an fMRI Study
This research project follows two main objectives: 1) Assess anatomical and functional cerebral abnormalities in bipolar disorder.
- Trial name
- BIP-ED (NCT01821469)
- Testing
- psychoeducation
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Attention Deficit/Hyperactivity Disorder, Bipolar Disorder
To Evaluate the Safety and Metabolic Profile of Vyvanse for the Treatment of ADHD in Euthymic Adults With Bipolar I/II Disorder
ADHD in the adult population is associated with several measures of harmful dysfunction. For example, adult ADHD is associated with high rates of separation/divorce and never-married status, lower educational attainment and…
- Trial name
- NCT01263548
- Testing
- lisdexamfetamine dimesylate
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- University Health Network, Toronto
Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group
ADOLESCENTS IMAGING USING fMRI: Feasibility Study
Impaired social cognition and cognitive control associated with borderline personality disorder (BPD) remain less explored. Recent Franco-Canadian study, has shown the feasibility of a neuroimaging tests in Quebec adolescents…
- Conditions
- Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group, Absence of Pathology on the CBCL and Ab-DIB for the Healthy Control Group, All Participants Were Euthymic at the Time of Task Administration
- Trial name
- ADO IMAGE (NCT07540429)
- Testing
- functional magnetic resonance imaging (fMRI)
- Where
- France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Etablissement Public de la Sante Mentale de la Somme
Past Major Depressive Episode, Euthymic
Social Stress and Suicide
Only vulnerable patients, when facing environmental stressors, attempt or commit suicide. Previous research demonstrated that suicide attempters usually misunderstand the social context and show impairments in decision making.
- Trial name
- SUPHY (NCT04714671)
- Testing
- The virtual version of the Social stress task : V-TSST
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Bipolar Disorder (BD)
Pain, Sleep Quality, Eating Habits and Physical Activity Level in Patients With Bipolar Disorder
Bipolar disorder (BD) is a complex condition characterized by recurrence of mania, hypomania, and depression. It is characterized by changes in daily life activities, sleep status, focus problems, and cognitive fluctuations.
- Trial name
- NCT06954350
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Kutahya Health Sciences University
Bipolar Disorder, Cognition
Antidepressant Treatments and Cognitive Function of Bipolar Patients
Patients with bipolar disorder (BD) have a wide range of neurocognitive dysfunction, which lead to impaired psychosocial function and reduced quality of life.
- Trial name
- NCT04564573
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Tianjin Anding Hospital
Bipolar I Disorder, Cognitive Impairment
Assessing the Role of Cariprazine in Improving Cognition in Euthymic Bipolar Patients
Some patients with bipolar disorder show broad cognitive impairments (e.g. difficulty with concentration, problem solving, memory etc.) that persist during euthymia (no symptoms of depression or mania) despite remission of mood…
- Trial name
- CARPZ-01 (NCT04771299)
- Testing
- Cariprazine
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Lakshmi N Yatham
Bipolar Disorder
Ramelteon for the Treatment of Insomnia and Mood Stability in Patients With Euthymic Bipolar Disorder
The purpose of this study is to determine whether treating sleep difficulties in patients with bipolar disorder also improves their mood stability.
- Trial name
- Ram-TIME (NCT00552760)
- Testing
- Ramelteon
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Lehigh Valley Hospital
Bipolar Disorder
Genetic Association Study Between GAD1 and Reelin Polymorphisms and GABA/Glutamate MRS in Bipolar Disorder Type 1 and Healthy Controls: SPECGENE PROJECT
Background: The pathophysiological mechanisms of bipolar disorder are not completely clarified and several hypothesis have already been formulated including the role of monoamines, gama amino butyric acid (GABA) and glutamate.
- Trial name
- SPECGENE (NCT01237158)
- Where
- Brazil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Bipolar Disorders, Euthymic Status
Evaluation of a Serious Game for Patients With Bipolar Disorder Involved in a Psychoeducation Group
Bipolar disorder is a condition characterized by succession of episodes- manic, hypomanic, and depressive episodes. Major risks factors of relapses are poor compliance, sleep disorder, and toxics consumption.
- Trial name
- Bipolife (NCT02936466)
- Testing
- Bipolife® group
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Montpellier
Bipolar I Disorder
Lurasidone and Cognition in Bipolar I Disorder
This is a 6 week, randomized, open-label, parallel group study in patients with Bipolar-I disorder (manic depression), who are in remission from an episode.
- Trial name
- NCT02147379
- Testing
- Lurasidone
- Where
- Canada
- Volunteers
- 53 people
- Sponsor
- University of British Columbia
Bipolar Disorder
A Trial of Cognitive Training in Euthymic Bipolar Disorder
Bipolar disorder (BD) is characterized by extreme changes in mood and emotion dysregulation. Mood changes are episodic in nature, with distinct periods of mania, depression, and asymptomatic periods of euthymia.
- Trial name
- NCT02476331
- Testing
- Working memory training
- Where
- Canada
- Sponsor
- University of Calgary
Bipolar Disorder Type II, Mood Depressive Disorder
Exploration of Differences in Metabolite Concentrations by NMR Spectroscopy in the Ventral Striatum, Anterior Cingulate Cortex and Prefrontal Cortex in Euthymic Patients With Unipolar and Bipolar Type II Mood Disorders, as Well as in Healthy Subjects
The presented project is an open and controlled single-center prospective exploratory study, evaluating the metabolic concentrations in the ventral striatum (VS), the Anterior cingulate cortex (ACC) and the prefrontal cortex…
- Trial name
- RMN-UNIBI (NCT05650788)
- Testing
- NMR spectrometry
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Bipolar Disorder, Insomnia
Cognitive Behavioral Therapy for Insomnia in Euthymic Bipolar Disorder
Patients with bipolar disorder suffer from sleep disturbances, even in euthymic phases. Changes in sleep are frequent signs of a new episode of (hypo)mania or depression.
- Trial name
- NCT01704352
- Testing
- Cognitive behavioral therapy for insomnia
- Where
- Norway
- Volunteers
- 38 people
- Sponsor
- Norwegian University of Science and Technology
Bipolar Disorder
Early Maladaptative Schemas Among Euthymic Patients With Bipolar Disorder in the Versailles FondaMental Advanced Centers of Expertise for Bipolar Disorders Cohort
Early Maladaptive Schemas (EMS) are overactivated in euthymic bipolar disorders (BD) and are associated with poor psychosocial functioning and higher suicidality.
- Trial name
- SPIBIP (NCT03977909)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Versailles Hospital
Social Cognition, Facial Emotion Recognition
Facial Emotion Recognition in Patients With Euthymic Bipolar Disorder I and II
The facial emotion recognition is a basic social skill for successful social interactions. Several meta-analyses and recent studies found impairments of the perception of facial emotions in patients with euthymic bipolar…
- Conditions
- Social Cognition, Facial Emotion Recognition, Facial Affect, Bipolar Disorder I and II
- Trial name
- REF-BIP (NCT05922956)
- Testing
- Facial emotion recognition test
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Patient With Bipolar Disorder, Euthymic Status
Cognitive Remediation on Patients With Bipolar Disorder and Memory Complaints
Bipolar disorder is a major health concern. Intercritical periods are marked with residual symptoms, both thymic and cognitive, which affects quality of life of patients, but also the quality of observance.
- Conditions
- Patient With Bipolar Disorder, Euthymic Status, Wirh Memory Complaints
- Trial name
- COGMED (NCT02988518)
- Testing
- COGMED program
- Where
- France
- Volunteers
- 41 people
- Sponsor
- University Hospital, Montpellier
Bipolar Disorder, Euthymic State
Study of Predictor of Mood Relapse in Bipolar Disorders
Study in 400 patients with bipolar disorder I or II, of relapse risk factors. The principal objective of this research is to test the predictive value of core vulnerability dimensions such as affective instability and emotional…
- Trial name
- RechuteBP (NCT02572674)
- Testing
- Experimental follow up, Genetic sample
- Where
- France
- Volunteers
- 274 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bipolar Disorder
Pilot Study: Mindfulness-Based Cognitive Therapy as a Tool for Prophylactic Mood Stabilizing Therapy in Bipolar Disorder
The purpose of this study is to evaluate the feasibility and short-term efficacy of MBCT as an add-on (i.e. patients must be stable with their regular mood stabilizing medication) for the maintenance therapy of bipolar disorder.
- Trial name
- NCT00999765
- Testing
- Mindfulness-Based Cognitive Therapy
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Douglas Mental Health University Institute