Clinical trials: Evaluation of CT in Coronary Artery Stenosis
Coronary Stenosis, Diabetic
Evaluation of the Functional Impact of Coronary Stenoses in Diabetics by Spectral CT
The optimal screening methods for coronary insufficiency, a frequent and pejorative complication in diabetics, are subject to debate, particularly in situations of silent myocardial ischemia.
- Trial name
- EURECAS (NCT05471687)
- Testing
- dual-energy dual-layer spectral scanner, Stress protocol with adenosin during dual-energy dual-layer spectral scanner
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Hospices Civils de Lyon
Aortic Valve Stenosis, Coronary Artery Disease
Correlation of FFR and iFR With Cardiac PET Perfusion in Patients With Severe Aortic Valve Stenosis
Aortic valve stenosis (AS) affects 2-7% of persons > 65 years, symptoms include: angina and dyspnea, dizziness and syncope. Coincidence of coronary artery disease (CAD), also presenting with angina and dyspnea, in patients with…
- Trial name
- TAVI PET (NCT04882488)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
Coronary Stenosis
Computed Tomography (CT) Coronary Angiogram Evaluation in Cancer Patients Having CT Thorax, Abdomen and Pelvis
Currently patients with certain cancer usually have routine follow up (Computed Tomography of Thorax, Abdomen and Pelvis) CT TAP scans to see response to treatment or relapse.
- Trial name
- NCT02275143
- Testing
- CT TAP Scan
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University Hospital Plymouth NHS Trust
Evaluation of CT in Coronary Artery Stenosis
Register Kardialer Computertomographie
The aim of this Heidelberg Cardiac CT Registry (Register kardiale Computertomographie) is to assess the diagnostic and prognostic perfomance of cardiac CT exminations in a real-world patient population.
- Trial name
- NCT03815123
- Testing
- cardiac CT
- Where
- Germany
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Das Radiologische Zentrum
Cardiology, Radiology
The Evaluation of the Roles of New Cardiac Imaging in Patients With Chest Pain
This is a prospective, observational study designed to evaluate the role of dynamic computed tomographic perfusion (CTP) and Computed Tomography-Derived Fractional Flow Reserve (CT-FFR) in patients presenting with chest…
- Conditions
- Cardiology, Radiology, Stenoses
- Trial name
- NCT03800862
- Testing
- CT-FFR and CTP
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Lancaster General Hospital
Coronary Artery Disease, Cardiovascular Diseases
Comparison of the Diagnostic Performance and Costs of FFRB Vs. Standard Care in Suspected Coronary Artery Disease.
Chest pain due to coronary artery disease (CAD) is a main driver of healthcare costs. Fractional flow reserve (FFR) measurement during invasive coronary angiography (ICA) is the gold standard to discriminate ischemia.
- Conditions
- Coronary Artery Disease, Cardiovascular Diseases, Cardiovascular; Stenosis, Coronary Occlusion
- Trial name
- ECONOMY (NCT06681584)
- Testing
- CTCA
- Where
- 3 sites in Singapore
- Volunteers
- 340 people
- Sponsor
- National Heart Centre Singapore
Coronary Artery Disease
Impact of Coronary CT Angiography, Physiologic Assessment and Pharmacotherapy on the Clinical Outcomes
The investigators aim to investigate the prognostic implication of stenosis and plaque features on coronary CT angiography (CCTA), physiologic assessment, and pharmacotherapy after invasive coronary angiography.
- Trial name
- PRIME-CT (NCT04547231)
- Testing
- Fractional flow reserve, Coronary CT angiography
- Where
- South Korea
- Volunteers
- 992 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease
Dual Source CT Angiography for Detection of Coronary Artery Stenoses
The trial will investigate the accuracy of Dual Source CT coronary angiography to detect coronary artery stenoses in patients with chest pain who have, based on clinical criteria, an intermediate likelihood for the presence of…
- Trial name
- MEDIC (NCT01190579)
- Where
- 8 sites in Denmark, Germany and 3 more
- Volunteers
- 398 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Coronary Artery Stenosis, Transcatheter Aortic Valve Implantation
Complete Functional Assessment of Intermediate Coronary Artery Stenosis Before and After Transcatheter Aortic Valve Implantation (TAVI) in Patients With Severe Symptomatic Aortic Valve Stenosis
The purpose of the current study is to assess complete coronary physiology (FFR, RFR, CFR, IMR, and CT-FFR) in TAVI candidates with intermediate coronary artery stenosis before and 6 months after TAVI.
- Trial name
- CHOICE-FR (NCT05133843)
- Testing
- Assession of complete coronary physiology
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Helios Health Institute GmbH
Transcatheter Aortic Valve Implantation (TAVI)
The EASE-IT CT Registry
ICA is not always required for a pre-TAVI workup of octogenarians and can be substituted by CTA resulting in a streamlined pre-procedural workup of patients without compromising patient safety.
- Trial name
- NCT05750173
- Testing
- Streamlining of the pre-procedural patient pathway
- Where
- 6 sites in Austria, Germany
- Volunteers
- 150 people
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Amyloidosis Cardiac, Stenosis Coronary
Non-Interventional Study on the Prevalence of Cardiac Amyloidosis in Patients With Higher-Grade Aortic Valve Stenosis - Evaluation Using Echocardiography, Computed Tomography, Tc99-SPECT/CT and Cardiac Magnetic Resonance Imaging (CMR)
Degenerative aortic stenosis (AS) is frequently accompanied by left ventricular hypertrophy and diastolic dysfunction, features that overlap with transthyretin (ATTR) cardiac amyloidosis.
- Conditions
- Amyloidosis Cardiac, Stenosis Coronary, TAVI(Transcatheter Aortic Valve Implantation)
- Trial name
- NIS-TAVI-AMY (NCT07752732)
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- University Hospital Tuebingen
Coronary Artery Disease
Evaluation of the Benefit of Exercise Testing for the Diagnosis of Obstruction in the Coronary Arteries of the Heart
The purpose of this study is to determine whether exercise testing can detect an obstruction in a coronary artery, and, thereby, can avoid performing a coronary imaging in some cases.
- Trial name
- DP-Cor-1 (NCT05140434)
- Testing
- Exercise test, Cardiac CT
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Sud Francilien