Clinical trials: Evaporative Dry Eye Disease
Evaporative Loss Dry Eye Disease
Study for Remote Investigation of Evaporative Dry Eye Disease
Dry eye disease is a common problem that can make your eyes feel uncomfortable and affect your vision, making daily tasks harder.
- Trial name
- I CRIED (NCT06976515)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of California, San Francisco
Dry Eye, Evaporative Dry Eye Disease
Microbiome-Focused Food Supplement for Evaporative Dry Eye Due to Meibomian Gland Dysfunction
Dry eye disease (DED) is a common chronic condition characterized by ocular surface discomfort and tear film instability. Evaporative DED associated with meibomian gland dysfunction (MGD) is a frequent phenotype and is often…
- Conditions
- Dry Eye, Evaporative Dry Eye Disease, Meibomian Gland Dysfunction (Disorder)
- Trial name
- NCT07453212
- Testing
- Dietary Supplement: Microbiome-targeted oral supplement
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Varol TUNALI
Dry Eye Disease, Dry Eye
Efficacy of Lipid-containing Artificial Tears in the Treatment of Dry Eye
This clinical study involves patients with Dry Eye Disease (DED) who are visiting an ophthalmology outpatient clinic. Eligible participants must have an Ocular Surface Disease Index (OSDI) score ≥14 and <50, and at least one…
- Conditions
- Dry Eye Disease, Dry Eye, Dry Eye, Evaporative
- Trial name
- NCT06955585
- Testing
- Proluxx Artificial Tear Spray
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- University Hospital Sestre Milosrdnice
Evaporative Dry Eye Disease
Comparative Efficacy Study to Demonstrate the Non-inferiority of I-DROP® MGD Versus 2 Competitor Eye Drops in Managing Evaporative Dry Eye
A Pilot Comparative study between I-DROP MGD vs two commercially available lubricant eye drops for the management of evaporative dry eye
- Trial name
- NCT06686368
- Testing
- I-DROP MGD, Theloze Duo, Systane Complete PF
- Volunteers
- 60 people
- Sponsor
- I-MED Pharma
Dry Eye, Dry Eye, Evaporative
Evaluation of Miebo (Perfluorohexyloctane) Eyedrops in Habitual Contact Lens Wearers
Miebo (Perfluorohexyloctane) is a novel, non-aqueous, single entity, preservative free, ophthalmic drop. This drop was recently approved by the Food and Drug Administration (FDA) for the treatment of Meibomian Gland Disease…
- Conditions
- Dry Eye, Dry Eye, Evaporative, Dry Eye Disease, Evaporative Dry Eye
- Trial name
- NCT06176651
- Testing
- Miebo
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Gordon Schanzlin New Vision
Evaporative Dry Eye Disease, Meibomian Gland Dysfunction
Clinical Study Using Eye Lipid Mobilizer (ELM) With Heat and Vibration To Treat Evaporative Dry Eye Disease
The goal of this clinical trial is to evaluate the Eye Lipid Mobilizer (ELM) for the treatment of evaporative dry eye disease associated with meibomian gland dysfunction.
- Trial name
- ELM (NCT06242860)
- Testing
- ELM
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Eyedetec Medical, Inc.
Meibomian Gland Dysfunction, Evaporative Dry Eye Disease
Comparison Between iLux and LipiFlow in the Treatment of Meibomian Gland Dysfunction (MGD): A 12-month, Multicenter Study
The purpose of this post-approval study is to demonstrate that iLux treatment offers comparable treatment effectiveness to LipiFlow for MGD treatment at 12 months post single treatment.
- Trial name
- NCT03956225
- Testing
- Systane iLux® Dry Eye System, LipiFlow® Thermal Pulsation System
- Where
- 15 sites in United States
- Volunteers
- 299 people
- Sponsor
- Alcon Research
Evaporative Dry Eye Disease
Effect of Thermal Pulsation System (Lipiflow) Treatment for Ocular Surface Disease Due to Meibomian Gland Dysfunction
Meibomian glands are a kind of sebaceous gland located in the tarsus of lower and upper lids and their function is to express lipids to the tear film.
- Trial name
- NCT03843983
- Testing
- Lipiflow® application
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA
Evaporative Dry Eye Disease
Safety and Efficacy of NovaTears® + Omega-3 (0.2%) Eye Drops on Signs and Symptoms of Dry Eye
This PMCF study is carried out following successful CE marking of NovaTears® + Omega-3 and is intended to generate systematic clinical data on the safety and performance of the device when used in accordance with the intended…
- Trial name
- NCT04521465
- Testing
- NovaTears® + Omega-3 (Perfluorohexyloctane with 0.2% w/w Omega-3 fatty acid ethyl esters)
- Where
- 2 sites in Germany
- Volunteers
- 36 people
- Sponsor
- Novaliq GmbH
Dry Eye Disease, Dry Eye Syndrome
Comprehensive Study on Dry Eye and Ocular Surface Disease Prior and After Cataract Surgery
Ocular surface disease (OSD), particularly dry eye, is one of the most common conditions seen by ophthalmologists. Dry eye (DE) is a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort…
- Conditions
- Dry Eye Disease, Dry Eye Syndrome, Evaporative Dry Eye, Cataract
- Trial name
- NCT04711642
- Testing
- The study will include three arms, one non interventional and 2 interventions. The intervention arms will include two commercially available sodium hyaluronate 0.1% (Systane ultra plus and Hylo-comod)
- Volunteers
- 100 people
- Sponsor
- Fundación Oftalmológica Los Andes
Meibomian Gland Dysfunction, Dry Eye Disease
Refractory Meibomian Gland Dysfunction and Plasma Jet
PURPOSE: The investigators propose a new treatment for refractory Meibomian Gland Dysfunction (MGD) patients with plasma jet to remove the hyperkeratinization layer from the lid margin to unblock terminal gland ducts and use…
- Conditions
- Meibomian Gland Dysfunction, Dry Eye Disease, Evaporative Dry Eye, Inflammation
- Trial name
- NCT04608942
- Testing
- Jett Plasma Medical Lift, Mechanical Debridement
- Where
- 2 sites in Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Primary Sjogren Syndrome, Secondary Sjogren Syndrome
Safety Study of the Use of Topical Cyclosporine in the Treatment of Dry Eye Disease
In the present study the investigators aim to determine the efficacy of an immunomodulating topical medication, compared with a topical lubricant, on the treatment of dry eye disease (DED) due to primary or secondary Sjögren's…
- Conditions
- Primary Sjogren Syndrome, Secondary Sjogren Syndrome, Aqueous Deficient Dry Eye Disease, Evaporative Dry Eye Disease
- Trial name
- NCT02004067
- Testing
- Restasis, Refresh Endura
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of São Paulo
Evaporative Dry Eye Disease
Evaluation of MAF-1217 in Patients With DED
This is a pre-market, multicentre, double-blind, randomized, crossover, non-inferiority study comparing the efficacy of MAF-1217 and Cationorm® in adult patients with evaporative DED.
- Trial name
- NCT03833882
- Testing
- MAF1217, Cationorm
- Where
- 2 sites in Italy
- Volunteers
- 72 people
- Sponsor
- VISUfarma SpA