Clinical trials: Evidence-based Clinical Practice
Evidence-Based Practice, Nurse's Role
Feasibility and Effectiveness of the Advancing Research and Clinical Practice Through Close Collaboration (ARCC)
The Institute of Medicine's (IOM) ambitious goal for at least 90% of clinical decisions to be evidence-based includes nursing interventions and practice.
- Trial name
- ARCC (NCT03269331)
- Testing
- CTEP EBP Immersion
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
Prostate Cancer, Risk Assessment
PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria
This study is a pilot trial that builds on findings from the validation of prostate cancer risk calculators in Nigerian men. The goal of the overall study is to improve the early detection of prostate cancer in a high-risk…
- Conditions
- Prostate Cancer, Risk Assessment, Clinical Decision Support Systems, Predictive Value of Tests
- Trial name
- PROACT (NCT07733440)
- Testing
- (a) Training and (b) Supported risk assessment
- Where
- Nigeria
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University
Pain, Obesity, Childhood
Sumamos Excelencia Project: Implementation of Best Practices in Clinical Practice (Thrid Edition)
There is a gap between research and clinical practice, leading to variability in decision-making. Multifaceted implementation strategies are for improving implementation of best practices.
- Conditions
- Pain, Obesity, Childhood, Breast Feeding, Incontinence, Urinary
- Trial name
- SE24 (NCT06522529)
- Testing
- Multifaceted implementation strategy
- Where
- Spain
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Instituto de Salud Carlos III
Decision Support Techniques, GRADE Approach
Defining Decision Thresholds for Judgments on Health Benefits and Harms: Study Protocol
The objective of this study is an approach to derive and use decision-thresholds for judgments on health benefits and harms using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Evidence to Decision…
- Trial name
- NCT05237635
- Testing
- descriptive case-scenarios
- Where
- Canada
- Volunteers
- 1,406 people, healthy volunteers welcome
- Sponsor
- McMaster University
Nursing Education, Evidence-Based Practice
Gamification Design in Evidence-Based Education for Clinical Nurses
The goal of this study is to compare the effectiveness of gamification versus group discussion in evidence-based practice (EBP) education for clinical nurses. It aims to improve learning outcomes and clinical application of EBP.
- Trial name
- NCT06531187
- Testing
- Evidence-Based Practice (EBP) Teaching
- Where
- Taiwan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ling-Yu Chien
Mental Health
Novel Methods for Implementing Measurement-Based Care for Youth in Low-resource Environments
This study will visit 4 community mental health clinics in Washington state and work with clinic staff to find out if staff are regularly evaluating clinical outcomes using questionnaires (which is also called measurement-based…
- Trial name
- NIMBLE (NCT05644756)
- Testing
- IMPACT Methods to Identify and Prioritize Determinants (Challenge I), Challenge and Match strategies to Prioritized Determinants (Challenge II)
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Dental Implants, Ceramic Implant
Zirconia Implants: Practice-based Evidence
This study is a prospective case series clinical study to examine the effectiveness of Ceramic dental implants manufactured by Swiss Dental Solutions (SDS).
- Trial name
- SDS (NCT06314425)
- Testing
- Immediate dental implants placements on fresh sockets after tooth extraction
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Swiss Dental Solutions
Clinical Practice, Nursing Education
The Effect of QR Code-Supported Perioperative Education Material Used in Clinical Practice
This study is planned as a randomized controlled trial to examine the effects of the use of QR (Quick Response) Code-supported materials prepared for perioperative care by nursing students during clinical practice on the…
- Conditions
- Clinical Practice, Nursing Education, Nursing Students, Evidence Based Nursing
- Trial name
- NCT06889077
- Testing
- QR Code Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Overweight, Obesity
Meta-analyses of the Effect of Liquid Meal Replacements on Cardiometabolic Risk
Obesity is a major risk factor for cardiovascular disease and diabetes. Weight loss is an important therapeutic goal for overweight and obese patients to reduce their risk of developing cardiovascular disease and diabetes.
- Conditions
- Overweight, Obesity, Type 2 Diabetes
- Trial name
- NCT02779790
- Testing
- Liquid Meal Replacements
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Diabetes, Prediabetes
Meta-analyses of Pasta as Part of Low Glycemic Index Diets and Adiposity
Pasta is an important example of a food which can lower the glycemic index (GI) of the diet, a property that has been exploited extensively in studies of low GI dietary patterns.
- Conditions
- Diabetes, Prediabetes, Overweight, Obesity
- Trial name
- NCT02961088
- Testing
- Pasta as part of a low GI/GL diet
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Evidence-Based Medicine, Physician-Nurse Relations
Advancing Research and Clinical Practice Through Close Collaboration (ARCC): A Pilot Test of an Intervention to Improve Evidence-Based Care and Patient Outcomes
The primary aim of this pilot study is to evaluate the effects of two variations of the ARCC Intervention Program on nursing processes and outcomes (job satisfaction, group cohesion, EBP knowledge, EBP implementation, EBP…
- Trial name
- NCT00635869
- Testing
- ARCC standard information, ARCC enhanced
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Surveys and Questionnaires, Evaluation of Processes and Results
Survey Stroke Units in Argentina
Introduction Patients who receive care from stroke units are more likely to survive their stroke, become independent, and return home.
- Conditions
- Surveys and Questionnaires, Evaluation of Processes and Results, Healthcare, Evidence-based Clinical Practice
- Trial name
- NCT06623253
- Testing
- not aplicable
- Where
- Argentina
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hospital de Rehabilitacion Manuel Rocca
Pain, Incontinence, Urinary
Sumamos Excelencia 2022
There is a gap between research and clinical practice, leading to variability in decision-making. Clinical audits are an effective strategy for improving implementation of best practices.
- Conditions
- Pain, Incontinence, Urinary, Obesity, Childhood, Breastfeeding
- Trial name
- NCT05466656
- Testing
- Continuous quality improvement cycle model
- Where
- Spain
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Teresa Moreno Casbas
Dyslipidemia, Diabetes
Meta-analyses of the Effect of Important Food Sources of Sugars on Cardiometabolic Risk Factors
Fructose-containing sugars have been implicated in the epidemics of obesity, diabetes and related cardiometabolic disorders. This view is supported by lower quality evidence from ecological observations, animal models, and select…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT02716870
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Prescribing
Testing CDS in OSCAR EMR Using STOPP Criteria
This mixed methods study seeks to assess and understand the impact of using an advanced CDS tool to present the STOPP criteria to support prescribers at the point of decision-making.
- Trial name
- STOPP-RCT (NCT02130895)
- Testing
- STOPP Criteria Decision Support Content
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Evidence Based Practice, Stroke
Adherence to Stroke Rehabilitation Guidelines Among Physical Therapists and Internship Students
The goal of this observational study is to learn about adherence to the 2024 VA/DoD Clinical Practice Guidelines for Stroke Rehabilitation among Turkish physiotherapists and internship students treating post-stroke patients.
- Conditions
- Evidence Based Practice, Stroke, Physical Therapist
- Trial name
- NCT07044817
- Testing
- Stroke Rehabilitation Guideline Adherence Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Medipol University
Overweight, Obesity
Network Meta-analyses of Artificially Sweetened Beverages and Cardiometabolic Risk
Sugars especially in form or sugar-sweetened beverages (SSBs) have been singled out as one of the prime culprits in the dual epidemics of obesity and diabetes.
- Trial name
- NCT02879500
- Testing
- Diet beverages
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Diabetes Mellitus, Type 2, Metabolic Syndrome X
Meta-analyses of Impotrant Food Sources of Sugars and Incident Cardiometabolic Diseases
There is an urgent need for stronger evidence to support recommendations for the role of sugars in diabetes and related cardiometabolic diseases.
- Conditions
- Diabetes Mellitus, Type 2, Metabolic Syndrome X, Hypertension, Cardiovascular Diseases
- Trial name
- NCT02702375
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Dyslipidemia, Diabetes
Meta-analyses of Fructose and Cardiometabolic Risk
Diabetes and heart associations continue to discourage high intakes of dietary fructose, a constituent part of the sucrose molecule that is found in fruits and vegetables as a natural sugar and in some processed foods and…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT01363791
- Testing
- Dietary fructose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Cardiovascular Disease, Diabetes
Meta-Analyses of Low-risk Lifestyle Behaviours and Patient Important Outcomes
Public health policy is universal in recommending the adoption of low risk low-risk lifestyle behaviors for health promotion and prevention of chronic or non-communicable diseases (NCDs).These behaviors generally include…
- Conditions
- Cardiovascular Disease, Diabetes, Cancer, Mortality
- Trial name
- NCT03234101
- Testing
- Low-risk lifestyle behaviours
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto