Clinical trials: Evoked Potentials
Neuropathic Pain
Development of Stimulator Pneumatic for Realization of Evoked Potential Allodynic/Somatosensory
The stimuli used in the evoked potentials are electrical or laser. They are started and synchronized with the collection of the EEG by signals TTL (transistor-transistor logic).
- Trial name
- STIMEA (NCT02527590)
- Testing
- pneumatic stimulations(allodynic area), pneumatic stimulations (healthy area), pneumatic stimulations no auditory masking
- Where
- France
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Sugammadex
The Effect of Sugammadex During Transcranial Electrical Motor Evoked Potential Monitoring in Spinal Surgery
Transcranial motor evoked potential (TcMEP) monitoring is conventionally performed during neurosurgical procedures without or with minimal neuromuscular blockade (NMB) because of its potential interference with signal…
- Trial name
- NCT04471376
- Testing
- Sugammadex
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Beijing Tiantan Hospital
Chronic Pain
Electrically Evoked Compound Action Potentials Human Observation Medtronic Algorithm Comparison Study
This is a prospective, multi-center, randomized, single-blind, cross-over, non-significant risk IDE research study to evaluate the in-clinic performance of a closed-loop algorithm in Spinal Cord Stimulation (SCS) therapy with an…
- Trial name
- ECHO-MAC (NCT04765735)
- Testing
- Open-loop testing, Closed-loop testing - External Spinal Cord Stimulator (SCS)
- Where
- 9 sites in United States
- Volunteers
- 52 people
- Sponsor
- MedtronicNeuro
Alzheimer´s Disease
Vagus Somatosensory Evoked Potentials and Near-infrared Spectroscopy in the Early Diagnosis of Dementia
In its long preclinical course, AD shows a spreading pattern of specific pathology in a uniform sequence of predictable steps including brainstem nuclei in early stages.
- Trial name
- Vogel (NCT02224326)
- Where
- Germany
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- University of Wuerzburg
Spinal Cord Injuries, Neurological Injury
Physiological Changes Induced Through MEP Conditioning in People With SCI
The study team is currently recruiting volunteers who are interested in participating in a brain-spinal cord-muscle response training study that aims to better understand the changes that take place in the nervous system as a…
- Conditions
- Spinal Cord Injuries, Neurological Injury, Paralysis, Spasticity, Muscle
- Trial name
- NCT04286191
- Testing
- Operant Conditioning, Control Group
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Medical University of South Carolina
Healthy Volunteers (HV)
Electrical Nerve Stimulation During Sleep for Memory Consolidation
The purpose of this study is to investigate the effects of transcutaneous electrical nerve stimulation (eTNS) applied during sleep on memory consolidation and brain-body physiological coupling.
- Trial name
- NCT07658274
- Testing
- 120 Hz Transcutaneous Electrical Nerve Stimulation, 2 Hz Transcutaneous Electrical Nerve Stimulation
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xidian University
Healthy Volunteers
VESTIBULAR EVOKED MYOGENIC POTENTIALS IN ALTERED GRAVITY
Recently, new clinical testing of saccular and utricular function have been developed and validated, the so-called vestibular-evoked myogenic potentials - VEMP (Brantberg et al. 2009, Cornell et al.
- Trial name
- VEMP (NCT03562676)
- Testing
- weightlessness
- Where
- France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Hearing Loss, Sensorineural, Bilateral Vestibulopathy
Effect of Hearing Loss and Vestibular Decline on Cognitive Function in Older Subjects
The world population has been growing and aging dramatically, with a rising prevalence of dementia. Worldwide, around 50 million people have dementia, with 10 million new cases added every year.
- Conditions
- Hearing Loss, Sensorineural, Bilateral Vestibulopathy, Alzheimer Disease, Mild Cognitive Impairment
- Trial name
- GECkO (NCT04385225)
- Testing
- Longitudinal follow-up
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Carotid Endarterectomy
Correlation Between New O3 Regional Oximetry, Electroencephalography and the Somatosensory Evoked Potential in Carotid Endarterectomy Surgery
Carotid endarterectomy (CEA) is one of the modalities to treat carotid artery disease. One of the perioperative complications of this surgery includes stroke, a condition that occurs when the blood supply to part of your brain is…
- Trial name
- NCT05267782
- Testing
- Masimo's O3 Regional Oximetry
- Where
- United Arab Emirates
- Volunteers
- 4 people
- Sponsor
- Cleveland Clinic Abu Dhabi
Aphasia, Stroke
Memantine and Intensive Speech-Language Therapy in Aphasia
Aphasia, the loss or impairment of language caused by brain damage, is one of the most devastating cognitive impairments of stroke. Aphasia can be treated with combination of speech-language therapy and drugs.
- Trial name
- NCT00640198
- Testing
- memantine, constraint-induced language therapy (CIAT)
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Gabinete Berthier y Martínez
Hemiplegic Cerebral Palsy
Spinal Cord Associative Plasticity in Cerebral Palsy
Associative plasticity has been used to promote functional recovery from conditions affecting movement. The long term goal of this project is to use electrical stimulation techniques to improve arm and hand function.
- Trial name
- SCAP-CP (NCT07607665)
- Testing
- Paired brain and nerve stimulation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Columbia University
Conscious Sedation, Deep Sedation
Effects of Two Different Sedation Regimes on Auditory Evoked Potentials and Electroencephalogram (EEG)
Sedation may be necessary in intensive care to facilitate diverse therapeutic interventions, but the use of sedative drugs may increase the risk of delirium and long-term cognitive impairment.
- Conditions
- Conscious Sedation, Deep Sedation, Critical Care
- Trial name
- NCT00641563
- Testing
- Dexmedetomidine, Midazolam, Remifentanil
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Monitoring of Depth of Anesthesia, AAI Index
Monitoring of Adequate Course of General Anesthesia
Clinical monitoring is the most common method of adjustment of the appropriate level of general anesthesia. However, the episodes of intraoperative awareness are still reported, suggesting that clinical observations may not be…
- Trial name
- MoDA (NCT03331692)
- Testing
- monitoring of the proper level of general anesthesia
- Where
- Poland
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Military Institute od Medicine National Research Institute
Concussion, Mild, TBI (Traumatic Brain Injury)
Evaluating a Novel Method of EEG Evoked Response Potential Analysis in Concussion Assessment
mTBI is widely recognized as a major public health concern in the United States and worldwide. mTBI diagnosis remains a clinical challenge as no single test can diagnose every concussion.
- Conditions
- Concussion, Mild, TBI (Traumatic Brain Injury), Mild Traumatic Brain Injury
- Trial name
- NCT03265912
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- ElMindA Ltd
Neuropathy;Peripheral
Evaluation of the Interest of Hypno-relaxation During Somatosensory Evoked Potentials
Somatosensory evoked potentials corresponds to a neurophysiological exam that studies the functioning of the sensitivity pathways.
- Trial name
- HYPOT (NCT04218448)
- Testing
- Hypnorelaxation
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Healthy
Anesthetics and Auditory, Visceral, and Heat Evoked Potentials
The aim of the present study is to investigate and quantify the influence of commonly used anesthetics on auditory and pain evoked potentials.
- Trial name
- NCT00534586
- Testing
- Propofol, Remifentanil, S-Ketamine
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Nervous System Diseases, Healthy Subjects
Functional Near-infrared Spectroscopy in Unconscious Patients
The study design is a single-center prospective pilot study. Hypothesis: Results of cerebral fNIRS examination in unconscious patients with severe hemorrhagic or ischemic stroke in the ICU are congruent with the results of SSEP…
- Trial name
- fNIRS (NCT04746820)
- Testing
- single-center prospective pilot study
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Emanuela Keller
Scoliosis
Anesthesiologic Management Effect on Perioperative Outcome in Scoliosis Surgery
Alteration of evoked potentials is described in cases with using inhalation anaesthetics. Muscle relaxants are contraindicated in case of motor evoked potentials except for initial dose for intubation of the patient.
- Trial name
- SCOL (NCT04423146)
- Testing
- The evocation of reproducible motor evoked potential according to the different BIS levels
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Brno University Hospital
Healthy Controls
Normative Data of Brain Network Activation in Adolescents and Young Adults
Establish normative data of ElMindA's Brain Network Activation (BNA) using evoked response in two age groups: adolescents and young adults.
- Trial name
- NCT01460394
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- ElMindA Ltd
Noise, Vestibular Disorder
Development of Bone-vestibular Evoked Myogenic Potential
This study aims to evaluate the effects of different masking conditions on cervical vestibular evoked myogenic potential (cVEMP) responses.
- Trial name
- NCT06711653
- Testing
- Vestibular evoke myogenic potential
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Taipei City Hospital