Clinical trials: Excretion
Healthy Postmenopausal Women, Absorption
A Clinical Study to Evaluate the Absorption, Metabolism, and Excretion of Oral [14C]GS1-144 in Healthy Postmenopausal Female Participants
This is a single-center, non-randomized, open-label, single-dose clinical PK study in healthy postmenopausal female participants.
- Conditions
- Healthy Postmenopausal Women, Absorption, Metabolism, Excretion
- Trial name
- NCT07537231
- Testing
- [14C]GS1-144
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Nutrition, Absorption, Metabolism and Excretion in Healthy Volunteers
Bioavailability of Omega-3 Fatty Acids From Fish Oil Supplements
This study is investigating whether a new type of fish oil supplement, in the form of soft chews, leads to better absorption of omega-3s in the body compared to traditional fish oil capsules.
- Conditions
- Nutrition, Absorption, Metabolism and Excretion in Healthy Volunteers, Fish Oils, Omega 3 Fatty Acids
- Trial name
- Ocean's O3 (NCT06665464)
- Testing
- Fish oil supplement 1, Fish oil supplement 2
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Wageningen University and Research
Absorption, Metabolism
Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-Simufilam Following a Single Oral Dose in Healthy Male Subjects
To evaluate the absorption, metabolism, and excretion of [14C]-simufilam in healthy male subjects following a single oral administration of 100 mg of (approximately 100 µCi) [14C]-simufilam.
- Conditions
- Absorption, Metabolism, Excretion
- Trial name
- NCT06195319
- Testing
- Simufilam
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cassava Sciences, Inc.
Absorption, Metabolism and Excretion in Healthy Volunteers, Bioavailability and AUC
Bioavailability Trial
Carrot is a unique vegetable owing to the availability of bioactive compounds polyacetylenes (PA) as well as carotenoids present in it.
- Trial name
- NCT06686004
- Testing
- Carrots
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Bioavailability, Metabolites
Bioavailability Study of Hemp Phenolics
The aim is to determine the bioavailability of the polyphenol fraction form a commercially available hemp hull fiber at two different amounts in generally healthy adults.
- Conditions
- Bioavailability, Metabolites, Excretion
- Trial name
- NCT06098001
- Testing
- Low dose dietary fiber, High dose dietary fiber
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Brightseed
Absorption, Metabolism and Excretion in Healthy Volunteers
A Phase 1 Study of the Absorption, Metabolism, and Excretion of [14C] PBI-200
This is a Phase 1, open-label non-randomized, single dose study in healthy male subjects.
- Trial name
- NCT05238337
- Testing
- [14C]-PBI-200
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Pyramid Biosciences
End Tidal Carbon Monoxide Excretion as a Diagnostic Tool for Hemolysis in the Newborn, Neonatal Jaundice
End Tidal Carbon Monoxide (ETCO): - A Tool to Aid Identification of Neonatal Hemolysis
The purpose of this study is to evaluate if adding a noninvasive testing of End Tidal Carbon Monoxide with a FDA approved device will help improve management of jaundice in the Neonates by reducing the number of lab draws, Coombs…
- Conditions
- End Tidal Carbon Monoxide Excretion as a Diagnostic Tool for Hemolysis in the Newborn, Neonatal Jaundice, End Tidal Carbon Monoxide
- Trial name
- NCT05475223
- Testing
- End Tidal Carbon Monoxide Value
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Urinary Sodium Excretion, Salt Intakes
Estimation Method of 24-hour Urinary Sodium Excretion by Using Spot Urine for Chinese Population
The accurate evaluation of daily salt or sodium intake is difficult to implement in clinical practice and large epidemiological studies.
- Trial name
- NCT03204422
- Testing
- No intervention
- Where
- China
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Beijing Children's Hospital
Healthy Volunteers, Biotin Excretion
Biotin Sample Collection Study
This protocol has been designed for a collection of urine samples from volunteers who will be given high dose biotin supplements over a period of 5 days, in order to provide a research sample bank to examine for biotin excretion…
- Trial name
- NCT03746821
- Testing
- Biotin
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
Diurnal Variation of Paracetamol Excretion
Estimation of Paracetamol in Urine to Assess the Diurnal Variation
Paracetamol is an antipyretic drug that is taken orally at different times of the day in same dose. It is excreted mainly through renal route which may show diurnal variation.
- Trial name
- NCT03122561
- Testing
- Paracetamol 500 mg tablet at morning, Paracetamol 500 mg tablet at midday, Paracetamol 500 mg tablet at night
- Where
- Bangladesh
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Fat Excretion, Energy Excretion
Calcium Intake and Fat Excretion
The overall purpose of this study is to examine the effect of calcium on fecal fat and energy excretion.
- Trial name
- KIFU/B266 (NCT01542164)
- Where
- Denmark
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Sodium Excretion by Urination
Natriuretic Effect of GLP-1in Healthy Non Obese Subjects
Adipose and diabetic patients have glomerular hyperfiltration and enhanced reabsorption of sodium in the kidney leading to fluid retention and hypertension.
- Trial name
- NCT02130778
- Testing
- Synthetic GLP-1 (1.5 pmol/kg/min) dissolved in 500 ml 0.9% saline, 500 ml 0.9% saline
- Where
- 2 sites in Croatia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Centre Zagreb
Metabolism and Excretion
An Open-label, Single-dose Study to Determine the Metabolism and Excretion of [14C]E2006 in Healthy Male Subjects
The purpose of this study is to determine the metabolism and excretion of [14C]E2006 in healthy male subjects.
- Trial name
- NCT02046213
- Testing
- E2006
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Healthy, Urine Phosphorus Excretion
A Study of ASP1585 to Evaluate the Bioequivalence Between ASP1585 Granules and ASP1585 Capsules
The purpose of this study is to assess the bioequivalence between ASP1585 granules and ASP1585 capsules after repeated oral administration of ASP1585 granules or ASP1585 capsules under open-label conditions in non-elderly healthy…
- Trial name
- NCT02531204
- Testing
- ASP1585
- Where
- Japan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
ABSORPTION, METABOLISM
Investigate Absorption, Metabolism and Excretion of [14C}-Proellex Following Single Oral Dose in Healthy Females
This study was to determine the ADME and metabolites of Proellex following a single oral dose of 25 mg.
- Conditions
- ABSORPTION, METABOLISM, EXCRETION
- Trial name
- NCT00881062
- Testing
- Proellex
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Repros Therapeutics Inc.
Reflux, Renal Excretion
Renal Impairment Study
The purpose of this study is to see how quickly AZD3355 is taken up in to the blood and leaves the blood in people with normal kidney function or with different degrees of reduced kidney function.
- Trial name
- NCT00863161
- Testing
- AZD3355
- Where
- 3 sites in Sweden
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Absorption, Distribution
Assess the Absorption, Distribution, Metabolism and Excretion of AZD7325 After Intravenous and Oral Administration
The purpose of this study is to evaluate the absorption, distribution, metabolism and excretion of AZD7325 after intravenous and 14C labeled oral dose
- Conditions
- Absorption, Distribution, Metabolism, Excretion
- Trial name
- NCT00940641
- Testing
- AZD7325
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- AstraZeneca