Clinical trials: Executive Function (Cognition), open to volunteers
Parkinson Disease
Cognitive-Motor Training for Gait Adaptability in Parkinson Disease
Cognitive-motor training combines thinking tasks with physical movements, encouraging participants to choose appropriate actions and adjust their movements according to different task demands.
- Trial name
- NCT07907718
- Testing
- Cognitive-motor training, Conventional physiotherapy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Yang Ming Chiao Tung University
Post-partum, Women
Creatine for Recovery and Thinking in Mothers
The purpose of this randomized, double-blind, parallel-group trial is to compare the effects of two doses of creatine monohydrate (5 g/day versus 10 g/day) administered for four weeks in postpartum women.
- Trial name
- CREATE-MOM (NCT07795853)
- Testing
- Creatine Monohdyrate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Bipolar Disorder and Major Depressive Disorder
Social Cognition, Memory, and Executive Functions in Bipolar Disorder and Major Depressive Disorder
Bipolar disorder (BD) are common psychiatric disorders often misdiagnosed, leading to delayed treatment. Even during stable phases, individuals with bipolar disorder experience residual cognitive impairments that affect their…
- Trial name
- COMET (NCT06740331)
- Testing
- Analysis of social cognition, memory functioning, and executive functioning processes
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Executive Function, Motor Skills
Influence of a Parent-mediated mHealth Motor Skill Intervention on Preschool Children's Motor Skills and Cognitive Function
The proposed study uses a mHealth application "app" to help parents teach their preschool-age child motor skill (FMS) activities in the home environment.
- Conditions
- Executive Function, Motor Skills, Healthy
- Trial name
- COSMIC (NCT07680075)
- Testing
- COSMIC
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Cervical Radiculopathy, Forward Head Posture
Correlation Between Forward Head Posture and Executive Functions in Cervical Radiculopathy
PURPOSE: This study aims to: Investigate the relationship between Forward Head Posture (FHP), Pain Intensity and executive functions in patients with Cervical Radiculopathy (CR).
- Trial name
- NCT07906847
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Cognition, Affect (Mental Function)
ETASCAN Project: ETAS Project 2
This study aims to investigate the chronic effects of ETAS® on cognitive, affective and neural outcomes in healthy adults aged 60-80 years with mild to moderate subjective cognitive complaints.
- Conditions
- Cognition, Affect (Mental Function), Sleep, MRI
- Trial name
- ETASCAN (NCT07550140)
- Testing
- ETAS®
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Reading
Motor-Cognitive Function, Dual-Task Walking
Effects of Adapted Argentine Tango Training Frequency on Dual-Task Walking
This randomized controlled trial will examine whether the frequency of adapted Argentine tango training affects walking and cognitive function in adults aged 55 to 60 years when the total weekly intervention time is kept the…
- Conditions
- Motor-Cognitive Function, Dual-Task Walking, Balance
- Trial name
- AAT-FREQ (NCT07800494)
- Testing
- Distributed Adapted Argentine Tango Training, Concentrated Adapted Argentine Tango Training, Health Education and Low-Intensity Stretching
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Xi'an Medical University
Older Adults (65 Years and Older), Fitness Testing
Health-related Physical Fitness and Executive Function in Older Adults: A Prospective Study
This study aims to explore the relationship between health-related physical fitness and behavioural and electrophysiological aspects of cool and hot executive function in older adults through a year prospective study design.
- Conditions
- Older Adults (65 Years and Older), Fitness Testing, Executive Function (Cognition), Prospective Study
- Trial name
- NCT07048561
- Testing
- observation alone
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Stroke, Attention Disorder
Virtual-reality Exercises for Alleviating Attention Deficits in Patients With Acquired Brain Injury
Stroke is the leading cause of long-term disability with an increasing incidence, especially in young adults. Among the cognitive difficulties following brain damage, deficits in attention are frequent and pervasive, affecting…
- Trial name
- NCT05728840
- Testing
- Immersive virtual reality gamified cognitive activities, Double neuropsychological standard activities
- Where
- Switzerland
- Volunteers
- 135 people
- Sponsor
- Mindmaze SA
Aging, Institutionalized Older Adults
Effects of Exercise, Cognitive Training, and Their Combination in Institutionalized Older Adults
The goal of this clinical trial is to learn if physical exercise, cognitive stimulation, or a combination of both can improve mobility, cognitive function, and psychosocial well-being in institutionalized older adults aged 65 and…
- Conditions
- Aging, Institutionalized Older Adults, Cognitive Abilities, Mobility and Independence
- Trial name
- NCT07082504
- Testing
- Physical Exercise Program, Cognitive Stimulation Program, Combined Physical Exercise and Cognitive Stimulation
- Volunteers
- 140 people
- Sponsor
- University of Salamanca
Psychopathy
Effects of Transcranial Magnetic Stimulation on Social Cognition, Cognitive Processing, and Functional Brain Architecture
This clinical trial will examine whether transcranial magnetic stimulation (TMS), a noninvasive form of brain stimulation, can influence social cognition, cognitive processing, and brain function in adults with elevated…
- Trial name
- NCT07635940
- Testing
- continuous theta burst stimulation (cTBS), Intermittent theta burst stimulation (iTBS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Preterm
Preschool Outcomes of a Previous RCT - ReDiMOM (NCT04540575)
This study will evaluate neurodevelopmental, health, and economic outcomes in preschool children born very preterm that participated in a randomized trial of an economic intervention designed to increase breastmilk feedings while…
- Trial name
- NCT07702357
- Testing
- This is a an observational prospective cohort study of a previous interventional trial (NCT04540575)
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- Rush University Medical Center
Mild Cognitive Impairment, Walking
Impact of a Multicomponent Exercise Program on Cognitive and Functional Outcomes in Patients With Mild Cognitive Impairment
The goal of this randomised clinical trial is to investigate the effectiveness of an innovative therapeutic exercise program emphasizing in dual-task exercises in people with amnestic Mild Cognitive Impairment.
- Conditions
- Mild Cognitive Impairment, Walking, Balance, Cognition
- Trial name
- MExeProMCI (NCT07334392)
- Testing
- Innovative therapeutic exercise program, Therapeutic exercise program, Flyer
- Where
- Greece
- Volunteers
- 45 people
- Sponsor
- University of Patras
Parkinson Disease
Cognitive-motor Training in Parkinson Disease
Literature reviews showed the cognitive-motor training that combines cognitive tasks may enhance cognitive functions more effectively than individual interventions.
- Trial name
- NCT06588439
- Testing
- Cognitive-motor training, Conventional physiotherapy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Yang Ming Chiao Tung University
Healthy
De-stressing the Brain: Can Eating Grapes During Periods of Mental Stress Protect Brain and Vascular Health in Young Adults
The main aim of the current study is to investigate whether consuming grapes rich in flavonoids just before mental stress can protect cerebrovascular and peripheral vascular function, mood and cognition, from the negative effects…
- Trial name
- NCT06923722
- Testing
- High-flavonoid grape intervention, Low-flavonoid grape intervention
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
TBI, Cognitive Dysfunction
Strengthening Neuro-Cognitive Skills for Success in School, Work and Beyond
For many Veterans, success in achieving goals at work, school and in other aspects of life are top priorities. The abilities to regulate attention, remember key information, and stay calm and on track are fundamental to this…
- Trial name
- NCT04109027
- Testing
- BrainStrong-BSR, BrainStrong-OPT
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Prader-Willi Syndrome
Effects of Transcutaneous Vagus Nerve Stimulation on Emotion Regulation and Executive Functioning in Prader-Willi Syndrome
The STIM-PRADER study aims to assess the effectiveness of auricular vagal neuromodulation therapy (aVNT) on emotional, behavioral, and cognitive domains impaired in Prader-Willi Syndrome (PWS).
- Trial name
- STIM-PRADER (NCT06720571)
- Testing
- Auricular vagal neuromodulation therapy (aVNT)
- Where
- 4 sites in France
- Volunteers
- 24 people
- Sponsor
- University of Bordeaux
Alzheimer Disease and Related Dementias, Cognition
Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome
The objective of this study is to determine the effects of a 6-month, home-based personalized transcranial direct current stimulation (tDCS) intervention targeting the left dorsolateral prefrontal cortex on cognitive function…
- Conditions
- Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
- Trial name
- TDCS4MCR (NCT06821568)
- Testing
- Personalized Transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States, Israel
- Volunteers
- 128 people
- Sponsor
- Hebrew SeniorLife
Cognitive Performance, Executive Function (Cognition)
Exploring the Cognitive Benefits of a Blackcurrant-Based Supplement in Normobaric Hypoxia
This study investigates the cognitive effects of Ārepa, a blackcurrant-based drink, under simulated high-altitude conditions (4,500m normobaric hypoxia for ~180 minutes).
- Conditions
- Cognitive Performance, Executive Function (Cognition), Working Memory, Hypoxia Induced Cognitive Impairment
- Trial name
- NCT07166835
- Testing
- Nootropics (ginkgo biloba, nicergoline, piracetam, or others)
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Pediatric Obstructive Sleep Apnea, Cognition
Observational Study on the Impact of Obstructive Sleep Apnea on Executive Function and Empathy Development in Children
This study aims to investigate the effects of obstructive sleep apnea (OSA) on executive function and empathy development in children aged 3-12 years.
- Conditions
- Pediatric Obstructive Sleep Apnea, Cognition, Empathy, EEG
- Trial name
- OSA-EFED (NCT06850220)
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Soochow University