Clinical trials: Executive Function Disorders
Traumatic Brain Injury
Transcranial Direct Current Stimulation and Computer-based Training for the Traumatic Brain Injury Rehabilitation
Traumatic Brain Injury (TBI) is a serious public health problem due to its high mortality and morbidity rates, mainly affecting young adult males.
- Trial name
- NCT03382626
- Testing
- anodal tDCS, Computer-assisted training
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Stroke, Cognitive Deficit
Transcranial Direct Current Stimulation (tDCS) in Post-Stroke Working Memory Deficits
The purpose of this study is to test the effects of tDCS (Transcranial Direct Current Stimulation) on stroke patients with working memory problems.
- Conditions
- Stroke, Cognitive Deficit, Cognitive Impairment, Short-Term Memory Impairment
- Trial name
- TDCS-PSMWD (NCT03034109)
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stony Brook University
Autism, ADHD
Spanish-language Executive Function Intervention for Children With Autism and/or ADHD
The goal of this clinical trial is to learn whether the Spanish-language version of Unstuck and On Target (SL-Unstuck), an executive functioning (EF) intervention, is feasible, acceptable, and effective for Spanish-speaking…
- Trial name
- NCT07084324
- Testing
- Unstuck and On Target
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Cognitive Impairment, Executive Dysfunction
Case Studies: Promoting Strategy Use in Functional Activities
The purpose of the study is to provide evidence of feasibility, acceptability, patient satisfaction, and patient perceived benefit of the Multicontext (MC) approach.
- Conditions
- Cognitive Impairment, Executive Dysfunction, Acquired Brain Injury
- Trial name
- NCT04363645
- Testing
- Multicontext (MC) approach
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Weill Medical College of Cornell University
Stroke, Ischemic
Cognitive Strategies for Optimizing Brain Health And Managing Transgenerational Vascular Risk Factors Post-Stroke
People living with the cognitive effects of stroke are at risk for recurrent stroke and further cognitive decline. Also problematic is that stroke risk clusters in families and biological family members of people who have…
- Trial name
- CHAMPS-TR (NCT06479174)
- Testing
- CHAMPS-TR
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Post Traumatic Stress Disorder, Mild Traumatic Brain Injury, Concussion
Rehabilitation of Executive Functioning in Veterans With PTSD and Mild TBI
One of the most pressing concerns within the VA currently is the provision of interventions that address the cognitive as well as emotional problems faced by Veterans with concurrent mild TBI and PTSD.
- Trial name
- NCT01921179
- Testing
- GOALS (Goal-Oriented Attentional Regulation), EDU (Brain Health Education)
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- VA Office of Research and Development
Heart Failure
Balance and Executive Function in Middle-age and Older Patients With Heart Failure in Post-Acute Care Program
This trial is a single-center clinical trial in Taiwan with an expected enrollment of 60 people in Taiwan. The purpose of this trial is to compare the performance of middle-aged and elderly patients with subacute heart failure…
- Trial name
- NCT06463496
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Chia-Jung
Obstructive Sleep Apnea
Obstructive Sleep Apnea Syndrome and Attention Executive Function Disturbances
Studies demonstrate that sleep disturbances are associated with cognitive dysfunction and attention deficit. However the correlation between the severity of obstructive sleep apnea and the degree of cognitive dysfunction was not…
- Trial name
- NCT00757796
- Volunteers
- 80 people
- Sponsor
- Assaf-Harofeh Medical Center
Motoric Cognitive Risk Syndrome, Mild Cognitive Impairment
Pre-demential Motoric Cognitive Risk Syndrome in Ageing Subjects
The main aim of the study is to characterize and understand the pathological mechanisms underlying the motoric cognitive risk syndrome, which is a predictor of Alzheimer disease.
- Conditions
- Motoric Cognitive Risk Syndrome, Mild Cognitive Impairment, Alzheimer Disease, Dementia
- Trial name
- PRESAGE (NCT05640141)
- Testing
- MRI evaluation, Actimetry & IMU, Gait evaluation
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Emotional Regulation, Virtual Reality
E-Emotio Project A Gamified Preventive School-based Paradigm Using Virtual Reality Technologies for Improving Emotional Regulation in Children and Adolescents.
Introduction and Significance: Preventive interventions have been shown to reduce the risk of developing anxiety and depression, making them a critical focus area in mental health promotion for children and adolescents.
- Conditions
- Emotional Regulation, Virtual Reality, Anxiety, Depression
- Trial name
- e-Emotio (NCT06236919)
- Testing
- VR cognitive training, VR nature exposure relaxation
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
ADHD
The Effectiveness of Cognitive-Functional Remote Group Intervention (Cog-Fun RG) for Adults with Attention Deficit Hyperactivity Disorder (ADHD)
The goal of this clinical trial is to examine the effectiveness of Cognitive-Functional Remote Group intervention (Cog-Fun RG). The main questions of this study are 1.
- Trial name
- ADHD (NCT06639139)
- Testing
- CogFun RG occupational therapy
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hebrew University of Jerusalem
Suicidal Ideation, Depressive Disorder
Reducing Suicide Risk in Older Veterans Using Problem Solving Therapy
Suicide is a national crisis, especially among older Veterans for whom evidence-based suicide prevention efforts are lacking. This proposal responds to the national priority to develop and improve interventions for suicide…
- Conditions
- Suicidal Ideation, Depressive Disorder, Anxiety Disorders, Post Traumatic Stress Disorder
- Trial name
- NCT04763330
- Testing
- Enhanced Usual Care (EUC), Problem Solving Therapy (PST) plus EUC
- Where
- 2 sites in United States
- Volunteers
- 117 people
- Sponsor
- VA Office of Research and Development
Autism, Autism Spectrum Disorder
Cognitive Training in Virtual Reality for Autism
The Virtual Reality Rehabilitation System (VRRS) is an innovative tool for motor and cognitive rehabilitation that has shown promising results in developmental populations, with evidence of feasibility, safety, acceptability, and…
- Trial name
- NCT07643649
- Testing
- Experimental Group, Control Group
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Cerebral Palsy
Cognitive Training Cerebral Palsy
This study aims to conduct a single-blind randomized controlled trial with sixty children with Cerebral Palsy (CP) to explore if a home-based computerized multi-modal executive training is effective improving infants' executive…
- Trial name
- ETCONNECT (NCT04025749)
- Testing
- Computerized Executive Functions training, Care as usual
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Barcelona
Exercise Intervention
Exercise Intervention on Conflict Monitoring in Children With Attention-deficit Hyperactivity Disorder
The study mainly investigates the effect of high-intensity interval training on conflict monitoring in children with ADHD by using event-related potential and sLORETA techniques.
- Trial name
- ADHD (NCT04112758)
- Testing
- High-intensity interval training
- Where
- Taiwan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Cognitive, Mood and Cognitive Performance
The Acute Effects of Onnit Alpha Brain on Cognition and Mood States
The purpose of this randomized, double-blind, placebo-controlled crossover study is to evaluate the efficacy of the acute effects of an investigational supplement (Alpha Brain or Alpha Brain 2.0) on improving cognitive…
- Conditions
- Cognitive, Mood and Cognitive Performance, Sleep Deprivation, Executive Function (Cognition)
- Trial name
- NCT07495592
- Testing
- Alpha Brain proprietary cognitive dietary supplement, Alpha Brain 2.0 proprietary cognitive dietary supplement
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Fibromyalgia, Executive Function
Effectiveness Pain Neuroscience Education In The Executive Functions In Patients With Fibromyalgia
Fibromyalgia (FM) is a chronic, complex and disabling clinical entity that has an average global prevalence of 2.7%. It occurs mainly in women in a 3: 1 ratio.
- Conditions
- Fibromyalgia, Executive Function, Neuroscience
- Trial name
- PNE (NCT05084300)
- Testing
- Pain Neuroscience Education, Usual care
- Where
- 2 sites in Colombia, Mexico
- Volunteers
- 62 people
- Sponsor
- Instituto Neurociencia Del Dolor
Neonatal Hyperbilirubinemia
Follow-up of Extreme Neonatal Hyperbilirubinemia in 5-10 Year Old Children: a Danish Population Based Study
The objective of this study was to investigate whether infants with total serum bilirubin > 450 umol/L in the neonatal period and no symptoms or no more than early acute bilirubin encephalopathy develop long term sequelae with…
- Trial name
- NCT01599611
- Testing
- Movement assessment battery for children - 2
- Volunteers
- 128 people
- Sponsor
- University of Aarhus
Autism Spectrum Disorder, High-functioning Autism
An Intervention Targeting Daily Adaptive Skills Through Executive Function Training for Adults With ASD
The current study is a single group pilot study of a novel intervention program which targets improvements in executive functions and adaptive skills in transition age young adults with high-functioning autism spectrum disorder.
- Conditions
- Autism Spectrum Disorder, High-functioning Autism, Autism
- Trial name
- NCT04418492
- Testing
- Skills for Adaptive Functioning through Executive training (SAFE; tentative title)
- Where
- South Korea
- Volunteers
- 7 people
- Sponsor
- Seoul National University Hospital
Attention Deficit Hyperactivity Disorder (ADHD)
Integrated Brain, Body and Social Intervention for Attention Deficit Hyperactivity Disorder (ADHD)
The investigators are conducting this randomized trial to determine if IBBS (Integrated Brain, Body, and Social)intervention is an effective treatment for ADHD (attention Deficit Hyperactivity Disorder) in two culturally distinct…
- Trial name
- IBBS (NCT01542528)
- Testing
- IBBS
- Where
- 5 sites in United States, China
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Yale University