Clinical trials: Executive Function Disorders
ADHD, Child, Only
A Randomized Controlled Study of Family Based EF Training for Schoolage Children With ADHD
The goal of this study is to provide a new treatment approach for schoolage children with ADHD, which could facilitate the EF developing well to achieve better outcome.
- Trial name
- NCT05025501
- Testing
- Family based Executive Function Training
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Psychotic Disorders, ADHD
Cognitive Remediation in Forensic Mental Health Care
Forensic patients often display cognitive deficits, particularly in the domain of executive functions, that represent a challenge to forensic rehabilitation.
- Conditions
- Psychotic Disorders, ADHD, TBI (Traumatic Brain Injury), Aggression
- Trial name
- CRFMHC (NCT04610697)
- Testing
- Cognitive Remediation, Active Control
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Executive Function Disorder, Obesity, Childhood
The Purpose of This Research is to Investigate the Effects of Aerobic Exercise on Executive Function in Obese Children
The goal of this clinical trial is to learn if aerobic exercise improves executive functioning in obese children. It will also understand the effects of aerobic exercise on executive functioning in obese children.
- Trial name
- NCT06510920
- Testing
- Aerobic exercise
- Where
- China
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Jing Xin
Autism Spectrum Disorder
Effects of Systematic Exercise Training on Core Symptoms, Executive Function and Brain Function in Children With ASD
Studies have shown that children with ASD simultaneously have deficits in overall executive function and impairments in basic motor skills, which have a negative impact on cognitive and social all-round development.
- Trial name
- NCT07104708
- Testing
- The Child-Parent- Trainer exercise program, The regular physical training
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Chen Li
22Q11 Deletion Syndrome, tACS
Using Transcranial Alternating Current Stimulation to Improve Executive Function in 22q11.2 Deletion Syndrome
The purpose of this project is to explore the effects of transcranial alternating current stimulation (tACS) in children, adolescents and young adults with a 22q11.2 microdeletion.
- Trial name
- NCT05664412
- Testing
- at-home tACS using Starstim-Home tES
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Stephan Eliez
Executive Functions in Cerebral Palsy
Personalized Innovative Intervention Pathways to Promote EF in Children With CP
Cerebral palsy (CP) is an umbrella term, covering a group of disorders of movement and posture. It is now accepted that CP represents much more than a disorder of movements considering the frequent association with a broad range…
- Trial name
- NCT06288971
- Testing
- Self-adaption web-based software for the rehabilitation of EF and visuo-spatial abilities, Tele-rehabilitation of EF and specific cognitive processes underlying academic skills, Game-based tools for the rehabilitation of EF and motor planning
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
Cognitive Impairment, Mild
Telerehabilitation Cognitive Impairments Following Chemotherapy Feasibility Study
Develop a game-based upper-extremity motor and cognitive rehabilitation system using custom and adaptable virtual reality simulations on a wearable device enhanced with biosensors.
- Trial name
- TCIFCF (NCT04972019)
- Testing
- Telerehabilitation Experimental Group
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Bright Cloud International Corp
Apathy, Mild Cognitive Impairment
Transcranial Magnetic Stimulation for Apathy in Mild Cognitive Impairment:Pilot Study
Mild cognitive impairment (MCI) is a precursor of dementia. Apathy, a profound loss of motivation, is a common behavioral problem in MCI.
- Trial name
- NCT02190019
- Testing
- Neurostar repetitive transcranial magnetic stimulator
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Central Arkansas Veterans Healthcare System
Congenital Heart Defect, Executive Function
Improving Neurodevelopmental Outcomes in Children With Congenital Heart Disease: An Intervention Study
Each year, approximately 1 child in every 100 is born with Congenital Heart Disease (CHD), making it the most common birth defect.
- Conditions
- Congenital Heart Defect, Executive Function, Children, Neurodevelopmental Disorders
- Trial name
- NCT03023644
- Testing
- Cogmed Working Memory Training
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Boston Children's Hospital
Opioid Use Disorder
Integrating Brain, Neurocognitive, and Computational Tools in OUD
The 5-year K01 Mentored Research Scientist proposal will employ brain, neurocognitive, and computational tools (e.g., machine learning) to understand the impact of opioid-use disorder (OUD) and common co-occurring issues on…
- Trial name
- NCT06136247
- Testing
- Neurocognitive battery, fNIRS
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- University of Pennsylvania
ADHD, Executive Function
Effectiveness of the Indonesian Computer-based Game
The aim of this study was to develop an Indonesian computer-based game prototype that targets the clinical symptoms of ADHD as well as executive function and to investigate effectiveness through fMRI BOLD examination.
- Trial name
- NCT04329663
- Testing
- Indonesian computer-based game prototype
- Where
- Indonesia
- Volunteers
- 10 people
- Sponsor
- Tjhin Wiguna
Migraine Disorders, COVID-19 Pandemic
The Impact of nCoV-2019 on Children With Migraine
Executive functions, anxiety and their relation to social participation and quality of life among children with Migraine during COVID-19 Backgrounds: Among children, especially adolescents, migraine stands out as one of the most…
- Trial name
- NCT06077006
- Testing
- questionnaires Only
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Bnai Zion Medical Center
Mild Cognitive Impairment
Using fMRI-guided TMS to Increase Central Executive Function in Older Adults (MCI_Sub)
This is an administrative supplement to an existing project "Using fMRI-guided TMS to increase central executive function in older adults: NCT02767323" This award allows extending our existing fMRI-TMS paradigm to patients with a…
- Trial name
- MCI_Sub (NCT04176406)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Duke University
Cerebrovascular Accident
Improvement of Executive Functions With the CO-OP Method in the Adult Subject After Stroke
The research focuses on top-down intervention approaches and more specifically on the Cognitive Orientation to daily Occupational Performance (CO-OP) method in the rehabilitation of executive function disorders in adult…
- Trial name
- FéCO-OPSA (NCT04282564)
- Testing
- Co-OP treatment
- Where
- France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Toulouse
Obesity
Promoting Child Inhibitory Control Skills Around Food
Today's environment provides many hedonic stimuli that promote consumption of unhealthy energy-dense snack foods. It is widely recognized that a systems approach is required to deal with this complex problem.
- Trial name
- CHIC Play (NCT02077387)
- Testing
- CHild Inhibitory Control (CHIC) Play, Attention control
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Anxiety Disorder, Head Injury
Neuropsychological Evaluation of Psychiatric and Neurological Patients
This study will allow researchers to use various types of tests to evaluate cognitive and sensory functions. These tests, referred to as "batteries" will evaluate attention, executive functions, general intellectual functioning…
- Conditions
- Anxiety Disorder, Head Injury, Mood Disorder, Schizophrenia
- Trial name
- NCT00001192
- Where
- 7 sites in United States, France and 1 more
- Volunteers
- 4,300 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Depression, Major Depressive Disorder
The Effects of Wellbutrin (Bupropion) on Residual and Cognitive Symptoms in SSRI-treated Depression
Many people with depression are treated with a serotonin-specific reuptake inhibitor anti-depressant (SSRI) and feel 'better'. Although many people feel 'better', they do not feel completely 'well'.
- Conditions
- Depression, Major Depressive Disorder, Unipolar Depression
- Trial name
- NCT00125957
- Testing
- Wellbutrin
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Mclean Hospital
ADHD, Perinatal
Expectant Moms Managing Attention-Deficit/ Hyperactivity Disorder
The goal of this study is to test a behavioral program for pregnant individuals with ADHD. This behavioral program focuses on skills for managing ADHD and related symptoms in pregnancy and postpartum.
- Conditions
- ADHD, Perinatal, Behavioral Intervention
- Trial name
- MomMA (NCT07001293)
- Testing
- MomMA Intervention, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pittsburgh
Attention Deficit Hyperactivity Disorder, Attention
Determining the Impact of Air Pollution on the Developing Brain
Background: Recent studies have linked exposure to airborne particulate matter (PM) to neurodevelopmental outcomes but the findings are mixed and mechanisms are unclear.
- Conditions
- Attention Deficit Hyperactivity Disorder, Attention, Executive Functioning, Social Functioning
- Trial name
- NeuroSmog (NCT04574414)
- Testing
- Psychological testing and MRI imaging
- Where
- Poland
- Volunteers
- 800 people
- Sponsor
- Jagiellonian University
Parkinson´s Disease
Gait Training With Executive Functions Tasks in Subjects With Parkinson´s Disease: A Study Protocol
The aim of this study is the development and implementation of a new protocol of a physical therapy training, based on a gait training associated with executive tasks, for treatment of individuals with Parkinson's Disease.
- Trial name
- NCT01650610
- Testing
- Gait training executive functions tasks
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo