Clinical trials: Executive Function Disorders
Child Development, Early Child Development
Intergenerational Risk and Resilience of Rohingya in Displacement
The iRRRd study is an ongoing prospective longitudinal prenatal birth cohort study based in Cox's Bazar, Bangladesh. Between February 2023 and March 2024, 2,888 pregnant women were enrolled (approximately 80% Rohingya refugees…
- Conditions
- Child Development, Early Child Development, Mental Health, PTSD - Post Traumatic Stress Disorder
- Trial name
- iRRRd (NCT07758283)
- Where
- Bangladesh
- Volunteers
- 2,200 people
- Sponsor
- New York University
Exercise, ADHD
Exercise Enhances Brain Function in Attention-deficit/Hyperactivity Disorder (ADHD)
The aim of the study was to investigate the different effects of exercise types on inhibitory control in children with attention-deficit/ hyperactivity disorder.
- Conditions
- Exercise, ADHD, Executive Dysfunction
- Trial name
- NCT05016102
- Testing
- Exercise type
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Schizophrenia, Schizoaffective Disorder
Clonazepam Effects on Brain Oscillations and Cognition in Schizophrenia
Cognitive deficits are some of the most prominent and disabling symptoms of schizophrenia. Evidence suggests that schizophrenia involves alterations to the functioning of a neural system under the control of a brain chemical…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
- Trial name
- KGB (NCT03061136)
- Testing
- Clonazepam
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Palo Alto Veterans Institute for Research
Executive Function, Social Interaction
Study: Effects of a Collaborative Occupational Therapy Interactive Vaulting
Occupational therapy services will be integrated into an interactive vaulting program which is an equine assisted activity. Children with disabilities ages 5-17 will participate.
- Conditions
- Executive Function, Social Interaction, Disability, Developmental
- Trial name
- NCT04481334
- Testing
- Collaborative occupational therapy interactive vaulting group
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- East Carolina University
Stroke
Study of Cognitive-Linguistic Profiles: The Role of Executive Control in Aphasia
In France, stroke affects 150,000 people annually and is the leading cause of acquired disability in adults; 10-12% of patients exhibit mild post-stroke aphasia, a condition defined by language difficulties.
- Trial name
- P-CLAC (NCT07766356)
- Testing
- Neuropsychological tests, Speech-language assessments
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Parkinson Disease
Cognitive-motor Training in Parkinson Disease
Literature reviews showed the cognitive-motor training that combines cognitive tasks may enhance cognitive functions more effectively than individual interventions.
- Trial name
- NCT06588439
- Testing
- Cognitive-motor training, Conventional physiotherapy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Yang Ming Chiao Tung University
Mild Cognitive Impairment
Calorie Restriction and Brain Function in Mild Cognitive Impairment
Problems with blood sugar metabolism (i.e., metabolic dysfunction) progressively develop through old age, which is primarily due to obesity and lack of physical activity.
- Trial name
- 5-2CR (NCT03872375)
- Testing
- Meal-Replacement Therapy, Dietary Counseling
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- Iowa State University
Acupuncture, ADHD - Attention Deficit Disorder With Hyperactivity
Acupuncture for ADHD: Acupoint Data Mining, Clinical Effectiveness, and Interviews to Explore Treatment Outcomes.
This study aims to evaluate the efficacy of acupuncture as a treatment for Attention Deficit Hyperactivity Disorder (ADHD) in children aged 6-12 years.
- Conditions
- Acupuncture, ADHD - Attention Deficit Disorder With Hyperactivity, Children, Interview
- Trial name
- ACU-ADHD (NCT06860763)
- Testing
- Chinese herbal medicine, Acupuncture
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The Third Affiliated Hospital of Beijing University of Chinese Medicine
Traumatic Brain Injury
Treatment Strategy to Prevent Mood Disorders Following Traumatic Brain Injury
The purpose of this study is to examine the efficacy of sertraline to prevent the onset of mood and anxiety disorders during the first six months after traumatic brain injury.
- Trial name
- NCT00704379
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Baylor College of Medicine
Primary Brain Tumor, Neurocognition
Executive and Socio-cognitive Functions in Survivors of Primary Brain Tumor: Impact on Patients' Quality of Life
Significant advances in primary malignant brain tumors (PBT) treatment have led to dramatically improved survival, both in children and adults.
- Conditions
- Primary Brain Tumor, Neurocognition, Quality of Life
- Trial name
- NEUROCOG-QOL (NCT02693405)
- Testing
- Executive functions, social cognition, quality of life
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Executive Functions, Metabolic Syndrome
Exergaming Improves Executive Functions in Patients With Metabolic Syndrome
Background: Recent studies indicate that exercise-related games can improve executive function, attention processing, and visuospatial skills.
- Conditions
- Executive Functions, Metabolic Syndrome, Aerobic Exercise
- Trial name
- NCT04015583
- Testing
- exergaming group
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Kyoung Im Cho
Parkinsonism or Parkinson's Disease Nos
Self-Reports of Executive Functions in Persons With Parkinson's Disease and Their Significant Others
The investigators are conducting a study to compare the self-reports of executive functions (that is to say, what role cognitive processes such as working memory and attention) in persons with Parkinson's Disease to the reports…
- Trial name
- NCT04928027
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
Attention Deficit Hyperactivity Disorder (ADHD), Brain Computer Interface
A Brain-Computer Interface-Based Attention Training Program Compared With Methylphenidate and Citicoline
The goal of this observational study is to learn whether a brain-computer interface (BCI)-based attention training program, used alone or together with medication, can improve attention, executive functioning, and emotional…
- Trial name
- Brain-Computer (NCT07333339)
- Testing
- Brain-Computer Interface-Based Attention Training
- Where
- Turkey (Türkiye)
- Volunteers
- 174 people
- Sponsor
- Uludag University
Cognitive Impairment
AI-Driven Cognitive Digital Therapeutics for Dementia Management
The study would investigate the effect of a cognitive digital therapeutics system. The intervention group would receive three digital therapeutics sessions per week for 8 weeks, while the control group would receive usual care.
- Trial name
- NCT06783465
- Testing
- Digital therapeutics session
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University WanFang Hospital
Attention Deficit Disorder With Hyperactivity, Executive Function Disorder
Neurofeedback-Based Digital Therapeutics for the Diagnosis and Treatment of ADHD in Children.
A multi-center, randomized controlled trial is being conducted to investigate the efficacy of a novel digital therapeutics (DTx) program that utilizes a cross-training approach between neurofeedback training and executive…
- Trial name
- ADHD (NCT06369714)
- Testing
- Concerta, Digital therapeutics
- Where
- 2 sites in China
- Volunteers
- 210 people
- Sponsor
- Lei Lei, MD
ADHD
Effects of Brain Breaks on Educational Achievement in Laboratory Settings: The Break4Brain Project
Advancement in teaching methods, together with the frenetic change in the lifestyles of the school population, provides a unique opportunity to advance scientific knowledge.
- Trial name
- NCT06303674
- Testing
- Physical activity with engaging cognitively, Physical activity without engaging cognitively
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
Autism Spectrum Disorder
Improving Executive Function in Korean Children With Autism
The purpose of this randomized controlled study is to evaluate the acceptability, feasibility, and preliminary efficacy of an executive function (EF) training intervention for 5- to 7-year-old autistic children in South Korea.
- Trial name
- NCT06523660
- Testing
- CHUCK CHUCK SKILLS: CHild's Understanding of Cognitive sKills, Parent Psychoeducation
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Korea University
Attention Deficit Hyperactivity Disorder
Neurocognitive Exercise Program for Children With Attention Deficit and Hyperactivity Disorder
The effects of Neurocognitive Exercise Program (NEP) on ADHD symptoms and executive functions in children with Attention Deficit and Hyperactivity Disorder (ADHD) will be investigated using The Conners parent rating scale-revised…
- Trial name
- NCT04707040
- Testing
- Neurocognitive Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Aging, Physical Activity
Exercise Periodization and Older Adults
The present study aimed at investigating the effects of two different resistance training protocols - nonperiodized (NP) and daily undulating periodization (DUP) - on hemodynamic, morphofunctional and cognitive parameters of…
- Conditions
- Aging, Physical Activity, Sarcopenia, Cognitive Decline
- Trial name
- NCT03443375
- Testing
- Physical exercise
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Traumatic Brain Injury, Closed Head Injury
Photobiomodulation to Improve Cognition in TBI, With fMRI
The purpose of this small, research study is to examine effectiveness of an at-home application of an experimental intervention, on thinking and memory in mild-moderate, closed-head, traumatic brain injury cases.
- Conditions
- Traumatic Brain Injury, Closed Head Injury, Cognitive Dysfunction
- Trial name
- NCT04230577
- Testing
- Real LED Intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Boston VA Research Institute, Inc.