Clinical trials: Executive Function Disorders
Indication for Modification of Patient Cognitive Status
Efficacy of Repyflec Cognitive Remediation Group Training in Schizophrenia
The purpose of this study was to develop an integrative intervention for schizophrenia taking into account previous efficacious therapies.
- Trial name
- NCT01279070
- Testing
- Repyflec cognitive remediation training
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Fundació Sant Joan de Déu
Parkinson's Disease, Mild Cognitive Impairment
A Trial of Neurocognitive and Supportive Therapy Interventions for Individuals With Parkinson's Disease
This randomized, controlled trial (RCT) evaluates the benefits of memory and problem solving training compared to supportive therapy in individuals with Parkinson's Disease with Mild Cognitive Impairment (MCI) and their support…
- Trial name
- NCT01646333
- Testing
- Memory and Problem-Solving Intervention, Supportive Therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Virginia Commonwealth University
Cerebrovascular Accident
Improvement of Executive Functions With the CO-OP Method in the Adult Subject After Stroke
The research focuses on top-down intervention approaches and more specifically on the Cognitive Orientation to daily Occupational Performance (CO-OP) method in the rehabilitation of executive function disorders in adult…
- Trial name
- FéCO-OPSA (NCT04282564)
- Testing
- Co-OP treatment
- Where
- France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Toulouse
Acquired Brain Injury
Exploring the Use of the Cognitive Orientation to Daily Occupational Performance Approach (CO-OP) With Children, Teenagers and Young Adults With Executive Functions Deficits Following Severe Acquired Brain Injury
Acquired brain injury (ABI) in childhood are the cause of disabling motor, cognitive and behavioural disorders, with severe consequences on the later development of autonomy and learning, with long-term repercussions on…
- Trial name
- REFECO-OP (NCT04560777)
- Testing
- CO-OP intervention
- Where
- 2 sites in France
- Volunteers
- 12 people
- Sponsor
- Hopitaux de Saint-Maurice
Traumatic Brain Injury
Executive Function Training Intervention for Chronic Traumatic Brain Injury
Traumatic Brain Injury (TBI) is a prevalent disorder developed by military personnel. While some individuals recover function within months after injury, others continue to suffer from cognitive problems months to years later and…
- Trial name
- NCT03704116
- Testing
- Expedition
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The University of Texas at Dallas
Healthy Volunteer
Effects of Interrupting Sedentary Behavior on Metabolic and Cognitive Outcomes in Children
Background: Some studies in adults have found that insulin and glucose blood levels are lower when a long period of sitting is broken up with walking, compared to sitting without breaks.
- Trial name
- NCT01888939
- Testing
- Walking on a Treadmill, Sedendary Activities Only
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cigarette Smoking
Investigation of Nicotine Seeking Behavior in Current Smokers
In this study, 21 non-treatment-seeking cigarette smokers were recruited to investigate the effects of acute stress on brain function and nicotine seeking/self-administration behavior.
- Trial name
- NSS (NCT03670212)
- Testing
- Yohimbine Hydrochloride, Hydrocortisone, Lactose Monohydrate Powder
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Wayne State University
Schizophrenia, Learning Disorders
Learning and Executive Function Disorders in Children and Psychosis Risk at Adult-age
The primary objective of the study aims to study transition toward schizophrenia in patients with learning disorders, and to compare the risk between patients with specific learning disorders, and patients with complexed learning…
- Conditions
- Schizophrenia, Learning Disorders, Executive Function Disorders
- Trial name
- DYS FUTURS UHR (NCT04280367)
- Testing
- Standardised semi-structured talk, Autistic spectre disorder screening, Anxiety measuring
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Non-specific Chronic Low Back Pain, Central Sensitization
Exercise Interventions for Overweight Men With Chronic Low Back Pain
This randomized controlled trial aims to compare the effectiveness of motor control exercise, aerobic walking exercise, and muscle strengthening exercise in overweight male adults with non-specific chronic low back pain and…
- Trial name
- MAMS-CLBP (NCT07688564)
- Testing
- Motor Control Exercise, Aerobic Walking Exercise, Muscle Strengthening Exercise
- Where
- Saudi Arabia
- Volunteers
- 156 people
- Sponsor
- Universiti Sains Malaysia
Executive Functions in Cerebral Palsy
Personalized Innovative Intervention Pathways to Promote EF in Children With CP
Cerebral palsy (CP) is an umbrella term, covering a group of disorders of movement and posture. It is now accepted that CP represents much more than a disorder of movements considering the frequent association with a broad range…
- Trial name
- NCT06288971
- Testing
- Self-adaption web-based software for the rehabilitation of EF and visuo-spatial abilities, Tele-rehabilitation of EF and specific cognitive processes underlying academic skills, Game-based tools for the rehabilitation of EF and motor planning
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
Obesity
Genetic Influences Between Cognitive Function and BMI
In this study the investigators will interrogate an existing data set to examine whether genetic variants contribute to an inverse association between weight status and cognitive function.
- Trial name
- NCT03116334
- Where
- United States
- Volunteers
- 869 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Autism Spectrum Disorder (ASD)
Cycling Interventions on Cognition in Children With Autism
The goal of this clinical trial was to determine if a specific type of cycling exercise improved executive functions in school-aged children with autism spectrum disorder (both boys and girls, aged 8-10 years, no healthy…
- Trial name
- Cycling&Autism (NCT07295912)
- Testing
- Learning to Bicycle, Bicycle Treadmill, Cycling with Training Wheels
- Where
- Hong Kong
- Volunteers
- 62 people
- Sponsor
- Chinese University of Hong Kong
Attention-deficit/Hyperactivity Disorder
Executive Functioning and Mindfulness in Adults With Attention Deficit/Hyperactivity Disorder Imaging
The main purpose of this study is to evaluate changes in brain functioning using an MRI machine following mindfulness meditation training.
- Trial name
- EFMImaging (NCT01629914)
- Testing
- Mindfulness Meditation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Alcohol Use Disorder
Effect of Repetitive TMS on Executive Function in Alcohol Use Disorder
Alcohol Use Disorder (AUD) is a major public health problem that affects the physical, social, family, and mental integrity of the sufferer.
- Trial name
- NCT05997212
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Mexico
- Volunteers
- 44 people
- Sponsor
- Universidad Nacional Autonoma de Mexico
Cognitive Impairments, RRSO
LDX for the Treatment of Cognitive Functioning Issues in Women Post-Oophorectomy
This is a double-blind, placebo-controlled, study testing whether LDX improves cognitive function and EF in 20 postmenopausal women who report onset of cognitive difficulties after oophorectomy (with or without subsequent…
- Trial name
- LDX (NCT01986777)
- Testing
- lisdexamfetamine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Autism Spectrum Disorder, High-functioning Autism
An Intervention Targeting Daily Adaptive Skills Through Executive Function Training for Adults With ASD
The current study is a single group pilot study of a novel intervention program which targets improvements in executive functions and adaptive skills in transition age young adults with high-functioning autism spectrum disorder.
- Conditions
- Autism Spectrum Disorder, High-functioning Autism, Autism
- Trial name
- NCT04418492
- Testing
- Skills for Adaptive Functioning through Executive training (SAFE; tentative title)
- Where
- South Korea
- Volunteers
- 7 people
- Sponsor
- Seoul National University Hospital
Stroke
Effects of the CO-OP Approach on Occupational Performance and Executive Function in Adults With Stroke
The purpose of this research study is to use the Cognitive Orientation to Daily Occupational Performance (CO-OP) approach with people who have experienced a stroke.
- Trial name
- NCT07127536
- Testing
- CO-OP (Cognitive Orientation to daily Occupational Performance), Standard Occupational Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Hacettepe University
Prader-Willi Syndrome
Effects of Transcutaneous Vagus Nerve Stimulation on Emotion Regulation and Executive Functioning in Prader-Willi Syndrome
The STIM-PRADER study aims to assess the effectiveness of auricular vagal neuromodulation therapy (aVNT) on emotional, behavioral, and cognitive domains impaired in Prader-Willi Syndrome (PWS).
- Trial name
- STIM-PRADER (NCT06720571)
- Testing
- Auricular vagal neuromodulation therapy (aVNT)
- Where
- 4 sites in France
- Volunteers
- 24 people
- Sponsor
- University of Bordeaux
Breast Cancer
Behavioral Weight Loss and Exercise After Treatment (BEAT)
Overweight and physically inactive breast cancer survivors are at increased risk of breast cancer recurrence and mortality. Cancer treatment-related changes that likely mediate weight loss and exercise success include the long…
- Trial name
- BEAT (NCT02052115)
- Testing
- 12 month exercise and weight loss intervention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Vermont
Schizophrenia, Cognitive and Executive Dysfunction
A Pilot Study of Adjunctive Structured Supportive Psychotherapy in Schizophrenia
This pilot randomized controlled trial examined whether adding structured supportive psychotherapy to risperidone treatment is more effective than risperidone alone in improving cognitive function and reducing peripheral…
- Conditions
- Schizophrenia, Cognitive and Executive Dysfunction, Neuroinflammation
- Trial name
- PILOT-SSP-SCZ (NCT07671040)
- Testing
- Structured supportive psychotherapy, Risperidone, Unstructured Supportive Conversation
- Where
- Indonesia
- Volunteers
- 44 people
- Sponsor
- Hasanuddin University