Clinical trials: Exercise
Dilated Cardiomyopathy, Heart Failure
PUFAs and Left Ventricular Function in Heart Failure
The purpose of this study is to test the hypothesis that n-3 PUFAs improve left ventricular systolic function in patients with stable chronic HF secondary to nonischemic dilated cardiomyopathy (NICM).
- Trial name
- CS-PUFA-02 (NCT01223703)
- Testing
- n-3 PUFAs
- Where
- Italy
- Volunteers
- 133 people
- Sponsor
- Università degli Studi di Brescia
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Chronic Fatigue Syndrome
The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome
Myalgic encephalomyelitis/Chronic fatigue syndrome (ME/CFS), otherwise known as Chronic fatigue syndrome (CFS) or myalgic encephalomyelitis (ME), is an under-recognized disorder whose cause is not yet understood.
- Conditions
- Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Chronic Fatigue Syndrome, Myalgic Encephalomyelitis, Exercise Intolerance
- Trial name
- NCT03674541
- Testing
- Pyridostigmine Bromide
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Brigham and Women's Hospital
Acute Deep Vein Thrombosis
Role of a Novel Exercise Program to Prevent Post-thrombotic Syndrome
Despite standard care, 25%-50% of patients with clots in the deep veins of the arms and legs progress to chronic post-clot problems resulting in significant disability, loss of productivity, and healthcare costs.
- Trial name
- EFFORT2 (NCT02148029)
- Testing
- Exercise, Standard Care
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- VA Office of Research and Development
Mild Cognitive Impairment
Preventing Loss of Independence Through Exercise (PLIÉ) in Persons With Mild Cognitive Impairment (MCI)
Nearly 1 in 10 older Americans have dementia, which is a devastating condition that leads to a progressive loss of independence and functional status.
- Trial name
- MCI PLIE (NCT03526146)
- Testing
- Behavioral: Preventing Loss of Independence through Exercise (PLIE)
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of California, San Francisco
Oxidative Stress
Examining Endogenous Antioxidant Levels in Well Trained Cyclists
This study will investigate whether increased habitual intake of antioxidant supplements effects the concentration of endogenous antioxidants, the response of antioxidants to exercise, and differences in oxidative damage compared…
- Trial name
- NCT02281851
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Down Syndrome
Promoting Health Through Parent Empowerment and the Activation of Routines (PrO-PEAR)
This study will examine the feasibility of the Promoting Health through Parent Empowerment and the Activation of Routines (Pro-PEAR) intervention using a open case-series for intervention optimization followed by a pilot RCT in…
- Trial name
- Pro-PEAR (NCT05020366)
- Testing
- Promoting Health through Parent Empowerment and the Activation of Routines, Enhanced Usual Care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Cognitive Aging, Adverse Childhood Experiences
Physical Exercise for Augmenting Cognitive Health (PEACH)
PEACH is a pilot project which is being conducted to determine the feasibility and acceptability of a 12-week home-based exercise intervention among Black and African American adults.
- Trial name
- PEACH (NCT04922710)
- Testing
- Home-based aerobic exercise
- Where
- 2 sites in United States, Jamaica
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Heart Failure With Preserved Ejection Fraction
The Effects of Ranolazine on Exercise Capacity in Patients With Heart Failure With Preserved Ejection Fraction
The purpose of this study is to determine whether treatment with Ranolazine will improve exercise capacity in patients with Heart Failure with preserved left ventricular ejection fraction, or HFPEF.
- Trial name
- RAZE (NCT01505179)
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Diego
Polycystic Ovary Syndrome
Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS
Polycystic ovary syndrome (PCOS) is the most common reproductive disorder in women of reproductive age and despite decades of research the etiology the disorder is not known.
- Trial name
- PULSE (NCT01482286)
- Testing
- Metformin, Dietary Restriction, Exercise Training
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Pennington Biomedical Research Center
Immune System and Related Disorders
Do NSAIDS or Executing Exercise Decrease Local Erythema, Site Swelling & Pain After INoculation
The purpose of this clinical investigation is to evaluate the efficacy and immunologic effects of a non-pharmacological exercise intervention (push-ups) compared to an oral NSAID (ibuprofen) and an oral placebo to decrease local…
- Trial name
- NLP (NCT02807623)
- Testing
- Ibuprofen, Compound Exercise of Push-ups
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Womack Army Medical Center
Dietary Habits
Tanglewood Trail Walking Program in Rural Kentucky 2020
The Tanglewood Trail Walking Program is a well established community health initiative that encourages community members to walk approximately 1 mile to the Whitesburg Farmers Market each Saturday.
- Trial name
- NCT05002985
- Testing
- walking group led by a community organizer
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Dawn Brewer
Breast Cancer, Depression
Hatha Yoga in Improving Physical Activity, Inflammation, Fatigue, and Distress in Breast Cancer Survivors
RATIONALE: Yoga may improve inflammation, fatigue, and depression in female breast cancer survivors. PURPOSE: This randomized clinical trial is studying how well Hatha yoga works in improving physical activity, inflammation…
- Conditions
- Breast Cancer, Depression, Fatigue, Pain
- Trial name
- NCT00486525
- Testing
- Yoga Therapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Aging
A New Adaptive Physical Activity Technology in Older Adults
The purpose of this study is to explore the feasibility and acceptability of a new physical activity technology (Jintronix) based on TV screen, virtual games and motion sensing cameras among pre-disabled older adults.
- Trial name
- Jintronix (NCT02467491)
- Testing
- Jintronix
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Florida
Chronic Obstructive Pulmonary Disease
An Exploratory Study, to Assess the Effect of Repeat-dose Inhaled Indacaterol Maleate (300 μg) on Dynamic and Static Lung Hyperinflation, Subjective Breathlessness and Health Status in Patients With Chronic Obstructive Pulmonary Disease(COPD)
This study evaluated the effect of QAB149 on dynamic and static hyperinflation, breathlessness, and health status in COPD patients
- Trial name
- NCT00636961
- Testing
- Indacaterol 300μg
- Where
- 3 sites in Germany
- Volunteers
- 27 people
- Sponsor
- Novartis
Hypoxia
Evaluation of the Attenuation by Aes-103 of Hypoxia Mediated Decrements in Endurance Exercise Performance
In low oxygen environments, such as high-altitude, some adults may become ill and suffer from acute mountain sickness. Further, all adults will find that exercising becomes much more difficult when compared with exercise at lower…
- Trial name
- NCT01871142
- Testing
- Aes-103
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Overweight, Obesity
ACTION PAC: Adolescents Committed to Improvement of Nutrition & Physical Activity
Using a previously created weight management program for adolescents, the intervention will be implemented through school-based health centers (SBHC) and will be delivered by SBHC providers trained in Motivational Interviewing.
- Trial name
- ACTION PAC (NCT02502383)
- Testing
- ACTION PAC, Communication with parents
- Where
- United States
- Volunteers
- 991 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Weight Change, Body, Behavior, Health
Increased Monitoring of Physical Activity and Calories With Technology
Since severe obesity in youth has been steadily increasing. Specialized pediatric obesity clinics provide programs to aid in reducing obesity.
- Conditions
- Weight Change, Body, Behavior, Health, Obesity, Childhood, Parent-Child Relations
- Trial name
- IMPACT (NCT03961061)
- Testing
- Brenner mFIT (standard care), Brenner mFIT (standard care plus mobile health components)
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Pediatric Obesity, Weight Loss
Our Lifestyles Our Lives
The purpose of the study was to examine the influence of step goals with pedometers to improve children's weight loss, physical activity, and psychosocial health during behavioral treatment.
- Trial name
- OLOL (NCT02965729)
- Testing
- Family-based weight management, Pedometer, Individualized step goals
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Pulmonary Arterial Hypertension
Effect of iNO on Invasively Derived Pulmonary Pressures in Patients With PAH
Pulmonary hypertension is characterized by an increase in the pressures in the blood supply to the lungs greater than a mean pressure of 25mmHg and a concomitant increase in overall pulmonary vascular resistance (PVR).
- Trial name
- NCT02734953
- Testing
- Nitric Oxide
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Obesity, Overweight
A Maintenance Program for the Be Fit Employee Wellness Program
This research study is being done: 1) to determine if the MGH Be Fit program helps employees to change their nutrition and exercise habits and lower their risk for chronic diseases, such as heart disease and diabetes and 2) to…
- Trial name
- NCT00707577
- Testing
- Internet-based maintenance program
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital