Clinical trials: Exercise Adaptation
Strength, Stress
Effects of Root Extract Ashwagandha (KSM-66) on Perception of Recovery and Muscle Strength in Adolescents Aged 11 to 19 Engaged in Grassroots Football
This study will test whether six weeks of ashwagandha (KSM-66 root extract), helps teenage footballers recover and improve strength.
- Conditions
- Strength, Stress, Exercise Adaptation, Sleep
- Trial name
- NCT07890935
- Testing
- Ashwagandha
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sports Performance and Applied Research in Trials and Analysis
Menopause, Exercise Adaptation
The Effects of Menopausal Status, Isoflavone Supplementation and Training on Cardiometabolic Function Women
The goal of this clinical trial is to investigate the role of estrogen and isoflavone supplementation in exercise-induced cellular signaling and cardiometabolic adaptations in premenopausal and postmenopausal women.
- Conditions
- Menopause, Exercise Adaptation, Mitochondrial Alteration, Vascular Function in Healthy Volunteers
- Trial name
- EXISO (NCT07878741)
- Testing
- Red Clover Isoflavone Supplementation, Supervised exercise training
- Where
- 2 sites in Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy Adult Participants, Exercise Training
The Effect of Olive Leaf Extract Supplementation on Training-induced Skeletal Muscle Functional and Molecular Adaptations in Healthy Volunteers
The goal of this study is to investigate the effect of combining olive leaf extract supplementation with endurance training (moderate intensity continuous training or sprint interval training).
- Conditions
- Healthy Adult Participants, Exercise Training, Neuromuscular Adaptations, Nutritional Intervention
- Trial name
- OLE_Training_1 (NCT07729072)
- Testing
- Olive leaf extract
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Exercise Training Adaptation
Physiological and Molecular Adaptations to Different Training Modalities in National-level Kayak Athletes
This interventional study evaluated physiological, molecular, and performance adaptations to different high-intensity training modalities in national-level kayak athletes.
- Trial name
- NCT07864012
- Testing
- High-Intensity Interval Training, Sprint Interval Training, Combined High-Intensity and Continuous Training
- Where
- Greece
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Supportive Care, Exercise Adaptations
Intradialytic Exercise and Cognitive Function
Exercise training may improve global and domain-specific cognitive function, mental health, psychological well-being, dialysis efficacy, and health-related quality of life in people with end-stage kidney disease receiving…
- Conditions
- Supportive Care, Exercise Adaptations, Exercise Training Therapy, Clinical Exercise
- Trial name
- EXCOG-HD (NCT07780175)
- Testing
- Resistance Training, Aerobic training, Combination Training
- Where
- Cyprus
- Volunteers
- 60 people
- Sponsor
- University of Thessaly
Altitude Training Adaptation, Cognitive Function
Effects of Bicarbonate Spring Water Immersion on Cognitive Reliability and Post-Maximal Exercise Recovery in Adolescent Rowers During Altitude Training: A Sex-Stratified Three-Arm Randomized Controlled Trial
This randomized controlled trial aims to investigate the effects of hot spring bath therapy on cognitive function recovery, cerebral hemodynamics, and athletic performance in athletes undergoing altitude training.
- Conditions
- Altitude Training Adaptation, Cognitive Function, Cerebral Hemodynamics, Exercise Performance
- Trial name
- NCT07608913
- Testing
- Control Group：Natural Recovery, Hot water immersion group, hot spring immersion group
- Where
- China
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Macao Polytechnic University
Endurance Running Performance, Exercise Training Adaptation
Effects of Two Endurance Training Programs on 5-km Running Performance in Recreational Runners
This study will examine the effects of two 8-week endurance training programs on 5-km running performance in recreational runners.
- Trial name
- NCT07738640
- Testing
- Lactate Threshold Training, Pyramidal-to-Polarized Endurance Training
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shuqi Jia
Muscle Hypotrophy, Exercise Performance
Resistance Training Adaptations and Caffeine Intake
This parallel-group, randomized, double-blind, placebo-controlled trial investigates the effects of three different caffeine supplementation strategies on resistance training-induced adaptations in 120 caffeine-naive, inactive…
- Conditions
- Muscle Hypotrophy, Exercise Performance, Muscle Strength, Adaptation
- Trial name
- NCT07410195
- Testing
- Caffeine (Constant Daily Dose), Caffeine (Escalating Dose), Caffeine (Training Days Only)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Athletic Performance, Physical Endurance
Event-Specific Adaptations to CrossFit and Running-Based HIIT in Elite Distance Runners at Moderate Altitude
The goal of this clinical trial is to compare the effects of two high-intensity training programs on physical performance and physiological adaptations in elite male middle- and long-distance runners aged 25 to 35 years who live…
- Conditions
- Athletic Performance, Physical Endurance, Altitude Training Adaptation, Aerobic Capacity
- Trial name
- NCT07675577
- Testing
- Running-Based High-Intensity Interval Training (HIIT), CrossFit-Based High-Intensity Training (CF)
- Where
- Iran
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Altitude Training Adaptation, Autonomic Nervous System
Effect of Hot Spring Therapy on Autonomic Nervous System and Exercise Performance During Altitude Training
This randomized controlled trial aims to investigate the effects of balneotherapy (hot spring bathing) on cardiac autonomic nervous system function and exercise performance in healthy athletes undergoing high-altitude training.
- Conditions
- Altitude Training Adaptation, Autonomic Nervous System, Hydrotherapy, Exercise Performance
- Trial name
- NCT07608887
- Testing
- Control Group：Natural Recovery, Hot water immersion group, hot spring immersion group
- Where
- China
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Macao Polytechnic University
Obesity &Amp; Overweight, Bariatric Surgery
Effects of Concurrent Aerobic and Resistance Training After Bariatric Surgery in Women: RCT
The purpose of this study is to evaluate the effects of a 12-week exercise program on body composition and various physical and physiological parameters in patients who have undergone bariatric surgery.
- Conditions
- Obesity &Amp; Overweight, Bariatric Surgery, Exercise Adaptation
- Trial name
- BARI-EX2023 (NCT07537543)
- Testing
- Aerobicexercise, Resistance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Gazi University
Resistance Exercise, Neuromuscular Adaptations
Comparison of the Effects of Free Weight and Machine-Based Exercises on Muscular Parameters
The aim of our study is to compare and investigate the effects of resistance exercises performed with free weights and those performed using machine systems on muscular parameters and neuromuscular control.
- Conditions
- Resistance Exercise, Neuromuscular Adaptations, Muscle, Adult
- Trial name
- NCT07495540
- Testing
- Machine-Based Resistance Exercise Group, Free Weight-Based Resistance Training Group
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Biruni University
Exercise, Overreaching
Impact of Training Load on the Gut miCrobiome And Its Relation to exeRcise Performance, mUscle Phenotype, and markerS of Overreaching in Healthy Men
The goal of this study is to learn how different amounts of supervised indoor cycling training change gut health (gut bacteria, the substances gut bacteria make, and the gut barrier integrity), and how these changes relate to…
- Conditions
- Exercise, Overreaching, Butyrate, Gut Microbiome
- Trial name
- ICARUS (NCT07481578)
- Testing
- Supplement, Moderate load exercise training, High load exercise training
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Stefan De Smet
Exercise Adaptation, Aerobic Capacity
AEROBIC ADAPTATION AND BIOMARKER RESPONSES IN COMBAT ATHLETES
This randomized controlled study investigates the effects of sport-specific training on aerobic adaptation and circulating biomarker responses in trained combat athletes.
- Conditions
- Exercise Adaptation, Aerobic Capacity, Athletic Performance, Combat Sports Training
- Trial name
- AERO-BIO (NCT07473440)
- Testing
- SPORT-SPECIFIC CONDITIONING PROGRAM
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Depression, Anxiety
Progressive Muscle Relaxation in Nursing Students: Effects on Psychological and Biopsychosocial Outcomes
This randomised controlled trial aims to investigate the effects of progressive muscle relaxation exercises (PMRE) on depression, anxiety, stress, future-oriented attitudes, and biopsychosocial responses in nursing students.
- Conditions
- Depression, Anxiety, Stress, Psychological, Mental Health
- Trial name
- PRMNURSE (NCT07038109)
- Testing
- Progressive relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Exercise Training Adaptation, Exercise Physiology
SPORT-SPECIFIC HIIT IN ELITE KICKBOXERS
This study examines how sport-specific high-intensity interval training (HIIT) affects the body in elite kickboxers. Participants are randomly assigned to either a HIIT training group or a control group.
- Conditions
- Exercise Training Adaptation, Exercise Physiology, High-Intensity Interval Training
- Trial name
- HIIT-KICK (NCT07449663)
- Testing
- Sport-Specific High-Intensity Interval Training, Regular Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Athletic Performance, Physical Fitness
Effects of 8-Week Plyometric Training on Basketball Performance and Isokinetic Strength
This study aims to evaluate the effects of an 8-week plyometric training program on the physical performance of male basketball players.
- Conditions
- Athletic Performance, Physical Fitness, Muscle Strength, Plyometric Exercise Adaptations
- Trial name
- PT-BASKET (NCT07399548)
- Testing
- 8-Week Progressive Plyometric Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Cardiac Autonomic Function, Hemodynamic Changes
Effects of Post-Match Foam Rolling, Static Stretching, and Passive Rest on Acute Cardiac-Autonomic, Hemodynamic, and Neuromuscular Recovery in National Wrestlers
This study looks at three common ways athletes recover after a wrestling match: foam rolling, static stretching, and resting. We want to learn which method helps the body recover better in the short time that athletes often have…
- Conditions
- Cardiac Autonomic Function, Hemodynamic Changes, Neuromuscular Adaptations, Exercise and Recovery
- Trial name
- NCT07305506
- Testing
- Foam Rolling, Static Stretching
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ali Kamil GÜNGÖR
HFrEF - Heart Failure With Reduced Ejection Fraction, Cardiac Rehabilitation
Predictive Factors of Response to Phase II Cardiac Rehabilitation in Heart Failure With Reduced Ejection Fraction
Exercise intolerance, measured as peak oxygen consumption (VO₂peak) during exercise in patients with heart failure with reduced ejection fraction (HFrEF).
- Conditions
- HFrEF - Heart Failure With Reduced Ejection Fraction, Cardiac Rehabilitation, Exercise Training, Exercise Adaptations
- Trial name
- PrédicRéa (NCT07164911)
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Centre Hospitalier de Corbie
Hypoxia, Cryostimulation
Evaluation of the Response to Hypoxia at Rest and During Exercise in a Healthy Subject After a Cryostimulation Exposure
Many information is available regarding human adaptations to cold or hypoxia. Adaptations to these environments and physical exercise constitute responses to physiological stress aimed at amplifying the organism's reactions and…
- Conditions
- Hypoxia, Cryostimulation, Metabolism, Autonomic Nervous System
- Trial name
- CRYOX (NCT06174480)
- Testing
- Cryostimulation
- Where
- 2 sites in France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital