Clinical trials: Exercise Capacity, open to volunteers
High Altitude, Healthy Adult
Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Healthy Individuals H
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on pulmonary resistance (sPAP/CO) and other hemodynamic outcomes in healthy individuals, who live permanently >2600m.
- Conditions
- High Altitude, Healthy Adult, Echocardiography, Pulmonary Resistance
- Trial name
- NCT07804485
- Testing
- Descent from 2850m to sea level
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Postpartum Physical Fitness and Functional Performance
Strong as a Mother
This study will evaluate Strong as a Mother, an existing community exercise program for women returning to exercise after childbirth.
- Trial name
- NCT07867275
- Testing
- Supervised Postpartum Functional Strength Training and Aerobic Conditioning
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Penn State University
Young Adult, Hypertension in Pregnancy
Cardiovascular Longitudinal ALSPAC Research Investigations Following Hypertensive Pregnancy in Young Adulthood
The purpose of this study is to understand more about why young people who were born to a hypertensive pregnancy may have increased risk of high blood pressure and are often at increased risk of heart and blood vessel disease…
- Conditions
- Young Adult, Hypertension in Pregnancy, Hypertension, Cardiovascular Diseases
- Trial name
- CLARITY (NCT05683093)
- Testing
- History of being born to hypertensive or normal pregnancy
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Oxford
Dilated Cardiomyopathy
Bromocriptine in Dilated Cardiomyopathy Among Women of Reproductive Age
Dilated cardiomyopathy (DCM) is a condition associated with left and /or right ventricular (LV) dilatation and systolic dysfunction without coronary artery disease or abnormal loading circumstances proportionate to the severity…
- Trial name
- NCT06250257
- Testing
- Bromocriptine mesylate plus standard GDMT
- Where
- Ethiopia
- Volunteers
- 112 people
- Sponsor
- Jimma University
Chronic Kidney Disease
Exploring the Effects of Exercise Combined With BFRT on Healthy and Patients With CKD
Investigate the effects of exercise training on the cardiopulmonary function and exercise capacity in healthy and CKD patients
- Trial name
- NCT07288905
- Testing
- Aerobic exercise, Blood flow restriction, Resistance exercise
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Obesity & Overweight, Prediabetes
Precision Nutrition for Obesity and Prediabetes Prevention in Under-supported Communities
This randomized controlled trial will evaluate the effectiveness of a culturally sensitive precision nutrition intervention for improving obesity- and diabetes-related outcomes among African American and Hispanic/Latino adults…
- Trial name
- PNOD (NCT07850531)
- Testing
- Precision Nutrition Intervention, Standard Nutrition Counseling
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Prairie View A&M University
Chronic Disease, Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight
Truway Diagnostic Tools in Primary Care
This study evaluates the effectiveness of Truway Health-sourced portable diagnostic devices, including ultrasound and blood glucose monitors, in early detection of chronic conditions in outpatient primary care settings.
- Conditions
- Chronic Disease, Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight, Hypertension, Cardiovascular Disease Acute
- Trial name
- TruDxPC (NCT07209527)
- Testing
- Truway Portable Ultrasound Device, Truway Blood Glucose Monitor, Standard Oral Hypoglycemic Agent
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Truway Health, Inc.
Cardiovascular Diseases, Cardiac Rehabilitation
Threshold-Based Versus Range-Based Exercise Intensity Prescription in Cardiac Rehabilitation
Cardiac rehabilitation is an important part of the treatment of patients with cardiovascular disease. Supervised aerobic exercise improves physical fitness, functional capacity, and quality of life.
- Trial name
- T-REXI-CR (NCT07908810)
- Testing
- Threshold-Based Aerobic Exercise Intensity Prescription, Range-Based Aerobic Exercise Intensity Prescription
- Where
- 9 sites in Belgium
- Volunteers
- 230 people
- Sponsor
- Hasselt University
Interstitial Lung Disease (ILD)
Efficacy of L-menthol on Breathlessness in Interstitial Lung Disease
The purpose of this study is to assess the effect of L-menthol on breathlessness and exercise capacity in patients with Interstitial lung disease (ILD).
- Trial name
- Ment-ILD (NCT07398287)
- Testing
- L-menthol
- Where
- 2 sites in Sweden
- Volunteers
- 20 people
- Sponsor
- Region Skane
Atrial Fibrillation (AF), Heart Failure (HF)
Effects of Enhanced External Counterpulsation Combined With Cardiac Rehabilitation in Patients With Atrial Fibrillation
This is a prospective randomized controlled trial designed to evaluate the effectiveness of enhanced external counterpulsation (EECP) combined with cardiac rehabilitation in patients with atrial fibrillation.
- Conditions
- Atrial Fibrillation (AF), Heart Failure (HF), Cardiac Rehabilitation
- Trial name
- EECP AF CR (NCT07058987)
- Testing
- Cardiac Rehabilitation Combined With EECP, Routine Medical Care
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Lanzhou University Second Hospital
Fibromyalgia Syndrome
Arm Exercise Capacity, Muscle Strength and Activities of Daily Living in Patients with Fibromyalgia Syndrome
The aim of this study is to compare the upper extremity exercise capacity, muscle strength and activities of daily living of patients with fibromyalgia syndrome and healthy individuals.
- Trial name
- NCT06678932
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Cardiovascular Diseases
Enhancing Capacity in Churches to Implement PA Programs
Despite the benefits of physical activity (PA) to prevent cardiovascular disease and other chronic diseases, few adult Latinas meet PA guidelines.
- Trial name
- NCT05473871
- Testing
- Faith in Action, Faith in Action+, Faith in Action++
- Where
- United States
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Sleep Disturbance, Aging
Sleep Quality in Assisted-Living Residents
Assisted living residents who have sleep disturbances are at great risk of developing cognitive impairments. The identification of factors that increase sleep problems in this population is the first step towards improving sleep…
- Trial name
- NCT04400617
- Testing
- Cross-sectional assessments to examine the relationship among sleep quality, functional/physical capacity, and cognitive performance.
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Calgary
Type 2 Diabetes
Periodization-Based Strength Exercise Training in İndividuals With Type 2 Diabetes
This randomized controlled study aims to compare the effects of different periodization-based strength training approaches in individuals with type 2 diabetes mellitus.
- Trial name
- T2DM_NLP (NCT07659925)
- Testing
- Non-linear Periodization-Based Strength Training, Linear Periodization-Based Strength Training, Usual Care
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Baskent University
Obesity & Overweight
Reliability and Validity of Physical Performance Tests in Individuals With Obesity
This study aims to investigate the reliability and validity of practical performance-based physical function tests in individuals with obesity.
- Trial name
- NCT07605793
- Testing
- Physical Performance Tests
- Volunteers
- 55 people
- Sponsor
- Yunus Emre Tutuneken
Fragility
Effects of VIVIFRAIL Program on Functional Capacity and Geriatric Syndromes in the Elderly.
The aim of this quasi-experimental, pretest-posttest study is to evaluate the effectiveness of the Vivifrail multicomponent physical exercise program in improving the functional capacity of pre-frail and frail older adults (aged…
- Trial name
- VIVIAL (NCT07436715)
- Testing
- Behavioral: Vivifrail multicomponent physical exercise program
- Where
- Spain
- Volunteers
- 86 people
- Sponsor
- Elena Pérez Expósito, MD
HFrEF - Heart Failure With Reduced Ejection Fraction
Impact of Barostimulation on Hemodynamics in Adults With Heart Failure
This study evaluates the effects of the implantation and adjustment of the CVRx Barostim device in adult patients with heart failure with reduced ejection fraction who are receiving maximally tolerated doses of guideline directed…
- Trial name
- BREATHE-HF (NCT07335510)
- Testing
- Baroreflex Activation Therapy
- Where
- 7 sites in United States
- Volunteers
- 58 people
- Sponsor
- Columbia University
Aortic Stenosis Disease
Clinical and CPET Parameters That Predict Improvement in Functional Capacity After TAVI
Determining Clinical and Cardiopulmonary exercise testing Parameters that may predict Improvement in Capacity After Transcatheter Aortic Valve Implantation
- Trial name
- NCT06833762
- Where
- Spain
- Volunteers
- 161 people
- Sponsor
- Hospital Clinic of Barcelona
Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease
Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on pulmonary resistance (sPAP/CO) and other hemodynamic outcomes in patients with pulmonary arterial hypertension PAH, who live permanently…
- Conditions
- Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease, High Altitude, Echocardiography
- Trial name
- NCT07804524
- Testing
- Descent from 2850m to sea level
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Silvia Ulrich Somaini
Mitral Insufficiency
Assessing the Relationship Between Symptoms and Mitral Regurgitnant. Severity
The current American College of Cardiology/American Heart Association (ACC/AHA) guidelines recommend surgery in patient with mitral regurgitation (MR) based on 1) the severity of MR and 2) the presence or absence of symptoms.
- Trial name
- NCT06738615
- Testing
- Pressure volume loop evaluation, cardiovascular magnetic resonance imaging, Cardiopulmonary exercise testing (CPET)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Atlantic Health System