Clinical trials: Exercise Capacity, open to volunteers
Pulmonary Hypertension Due to Lung Disease (Disorder)
Influence of Cardiopulmonary Rehabilitation on Cardiorespiratory Adaptation in Patients With Pulmonary Hypertension
This study aims to investigate the effect of cardiopulmonary rehabilitation on cardiorespiratory parameters and functional capacity in patients with pulmonary hypertension.
- Trial name
- NCT07648524
- Testing
- cardiopulmonary rehabilitation in the form of moderate-intensity interval aerobic training, Inspiratory Muscle Training, Medical treatment
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Polyneuropathy, Charcot Marie Tooth Disease (CMT)
Effects of Resistance Exercises in Hereditary Sensory-Motor Neuropathy (Charcot-Marie-Tooth Disease)
The goal of this clinical trial is to compare the effects of an 8-week resistance exercise training program on skeletal muscle quality, functional capacity, and quality of life in young individuals aged 15 to 29 years, with and…
- Trial name
- PNP (NCT07152197)
- Testing
- Progressive Resistance Exercise Training
- Where
- 2 sites in Chile
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Alzheimer's Dementia (AD), Alzheimer Disease (AD)
Exercise in Alzheimer's Disease: Functional Biomarkers
Alzheimer's disease (AD) is the leading cause of dementia worldwide and involves systemic alterations beyond the brain, such as loss of muscle strength, chronic low-grade inflammation, and gut microbiome dysbiosis.
- Trial name
- AD-GUT-EX (NCT07918417)
- Testing
- High load, Moderate load, Healthy adults - High load
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- European University Miguel de Cervantes
Burpee Exercise, Water Exercises
Water Based Burpee Exercises on Functional Capacity in Poste-menopausal Women After Thyroidectomy
Skeletal muscle mass plays an important role with both metabolism and functional capacity. It is well established that the aging process leads to a significant decline in both muscle mass and strength which is associated with…
- Conditions
- Burpee Exercise, Water Exercises, Functional Capacity, Postmenopausal
- Trial name
- NCT07052279
- Testing
- water based burpee exercises, aerobic exercises
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Zaytoonah University of Jordan
Eccentric Exercise, Home-based Training
Effects of Eccentric Training at Long Muscle Length on Functional Capacities of Elderly Adults
As aging leads to a decline in muscle function and overall physical performance, interventions targeting muscle strength and neuromechanical properties are critical for maintaining functional independence in older adults.
- Conditions
- Eccentric Exercise, Home-based Training, Elderly Adults
- Trial name
- EMULE (NCT06953258)
- Testing
- Home-based eccentric training at long muscle length, Conventional home-based training
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Robin Souron
Lipedema, Exercise Therapy
Investigation of the Effects of High-Intensity Interval Exercise and Moderate-Intensity Continuous Exercise on Limb Volume, Functional Capacity, and Quality of Life in Patients With Lipedema
This randomized controlled clinical study aims to investigate and compare the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT), when combined with intermittent pneumatic…
- Conditions
- Lipedema, Exercise Therapy, High Intensity Interval Training
- Trial name
- NCT07319611
- Testing
- Intermittent Pneumatic Compression (IPC), Home-Based Walking Program, High-Intensity Interval Training (HIIT)
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Marmara University
Cardiovascular Diseases, Exercise
Evaluation of the Effectiveness of Physical Exercise on Aerobic Capacity in Patients With Cardiovascular Disease
According to the Pan American Health Organization (PAHO), non-communicable chronic diseases-primarily cardiovascular diseases-are the leading cause of death and disability worldwide.
- Conditions
- Cardiovascular Diseases, Exercise, Aerobic Capacity
- Trial name
- NCT07019506
- Testing
- Cardiac rehabilitation
- Where
- Colombia
- Volunteers
- 200 people
- Sponsor
- Fundacion Universitaria Maria Cano
Chronic Respiratory Disease, Chronic Obstructive Pulmonary Disease
High-Intensity Interval Alternating Concentric-Eccentric Training in Chronic Respiratory Disease
This randomized controlled trial aims to evaluate the effects of high-intensity interval training incorporating alternating concentric and eccentric cycling on functional performance in adults with chronic respiratory disease…
- Trial name
- Effects of Hig (NCT07867535)
- Testing
- Alternating Concentric-Eccentric High-Intensity Interval Training, Concentric High-Intensity Interval Training, Usual Care
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Fu Jen Catholic University Hospital
Physical Inactivity, Phosphate Overload
Impact of Dietary Phosphate Excess on Exercise Capacity and Visceral Adiposity
Studies in mice demonstrated that dietary phosphate (Pi) loading that mimic the level of US adult consumption leads to reduced spontaneous locomotor activity, exercise capacity, and reduced resting metabolic rate when in normal…
- Conditions
- Physical Inactivity, Phosphate Overload, Visceral Obesity
- Trial name
- NCT05147909
- Testing
- Sodium Phosphate, Sodium Chloride
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Single-ventricle, Stenosis
Transcatheter Fontan Stenting: Impact on Hepatic Stiffness and Exercise Capacity
The goal of this observational study is to assess the clinical impact following Fontan stent placement for extracardiac Fontan conduit (EFC) stenosis in patients with single-ventricle Fontan-palliated patients ages 12-21 years…
- Trial name
- NCT07073612
- Testing
- Cardiopulmonary Exercise Testing (CPET), Shear Wave Elastography Scan
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital Los Angeles
Aerobic Exercise, Lipedema
Comparison of Different Exercise Protocols for Diagnosed With Lipedema
This study was designed to compare the effects of high-intensity interval training and moderate-intensity continuous training on functional capacity, muscle strength, and quality of life in patients with lipedema, and to…
- Trial name
- NCT07873541
- Testing
- High-Intensity Interval Aerobic Exercise Group, Moderate Intensity Continuous Group
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Hitit University
Spina Bifida
Motor Imagery-Supported Thoracic Expansion in Children With Spina Bifida
This study will investigate whether adding motor imagery to thoracic expansion exercises can improve respiratory function in children with spina bifida.
- Trial name
- NCT07846202
- Testing
- Thoracic Expansion Exercises, Motor Imagery-Supported Thoracic Expansion Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karabuk University
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Phase I Randomized Controlled Trial of Functional Resistance Training in Older Cancer Survivors: The ACES Trial
The study will assess the feasibility and preliminary efficacy of live, online supervised group functional resistance training in older cancer survivors who may have difficulty with independent functioning.
- Conditions
- Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm, Cancer, Functional Limitation
- Trial name
- ACES (NCT07606313)
- Testing
- Functional Resistance Training, Stretching, Delayed Functional Resistance Training
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- OHSU Knight Cancer Institute
Non-cystic Fibrosis Bronchiectasis
Breathing Training and Exercise Capacity in Non-CFB
The purpose of this research is to investigate whether a home-based and health coach supported specific breathing and respiratory muscle training program improves the ability to exercise, the function of the lungs and breathing…
- Trial name
- NCT05860803
- Testing
- LungTrainers, LungTrainers Pulmonary Rehabilitation regime
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Parkinson's Disease (PD)
The Effects of Ballet-Based Exercise Training on Respiratory Functions, Balance, Cognitive Functions, Peripheral Muscle Strength, Functional Capacity and Quality of Life in Patients With Parkinson's Disease
This study investigates the impact of an 8-week ballet-based dance therapy on people with Parkinson's disease. It aims to assess the effect of ballet on motor and non-motor symptoms, such as balance, cognitive function…
- Trial name
- NCT06986941
- Testing
- Ballet-Based Dance Therapy, Standard Care with Exercise Counseling
- Volunteers
- 24 people
- Sponsor
- Bezmialem Vakif University
Smoking, Tobacco
Respiratory Function and Oxygenation in Smokers and Non-smokers
This study aimed to compare respiratory function, exercise capacity, and intercostal muscle oxygenation in healthy smokers and non-smokers.
- Trial name
- NCT07027956
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease
Sleep-Assessment in Patients Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on sleeping parameters by polygraphy in patients with pulmonary arterial hypertension PAH, who live permanently >2600m.
- Conditions
- Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease, Polygraphy, Sleep
- Trial name
- NCT07801963
- Testing
- Descent to sea level
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Silvia Ulrich Somaini
Amyloid Cardiomyopathy, Transthyretin Cardiac Amyloidosis
Exercise Training in Transthyretin Cardiac Amyloidosis
Transthyretin cardiac amyloidosis causes debilitating heart failure in older adults. The proposed research will develop a personalized exercise training program to improve functional capacity in patients on optimal treatment for…
- Trial name
- NCT05797857
- Testing
- Exercise Training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Brigham and Women's Hospital
Heart Failure, Inspiratory Capacity
Inspiratory Muscle Training in Hospitalized Heart Failure Patients
Introduction Exercise intolerance is the most common symptom in patients with heart failure (HF), significantly impacting their quality of life and functional capacity.
- Conditions
- Heart Failure, Inspiratory Capacity, Inspiratory Muscle Strength, Hospitalizations
- Trial name
- IMTHHF (NCT07108231)
- Testing
- Inspiratory muscle trainning
- Where
- 2 sites in Brazil
- Volunteers
- 30 people
- Sponsor
- CAROLINA NIGRO DI LEONE
Acute Myocardial Infarction (AMI), PCI Patients
The Effect of Cardiac Rehabilitation on Left Ventricular Remodeling in Patients Undergoing Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction
Cardiac rehabilitation has proven to improve the functional capacity of patients who had acute myocardial infarction. However, its effect on Left ventricular remodeling following an MI event treated with Primary PCI is not yet…
- Conditions
- Acute Myocardial Infarction (AMI), PCI Patients, Percutaneous Coronary Intervention (PCI), Primary Percutaneous Coronary Intervention
- Trial name
- NCT07155928
- Testing
- Cardiac Rehabilitation, Primary Percutaneous Coronary Intervention
- Volunteers
- 100 people
- Sponsor
- Assiut University