Clinical trials: Exercise Induced Asthma
Exercise-induced Bronchospasm
Bronchoprotective Effect of Arformoterol in Children With Exercise-Induced Bronchospasm (EIB)
It is our primary hypothesis that pretreatment with arformoterol will provide superior protection against EIB in children with mild-moderate asthma compared to placebo added to the current asthma regimen.
- Trial name
- EIB (NCT00662779)
- Testing
- arformoterol, formoterol
- Where
- United States
- Sponsor
- University of New Mexico
Exercise Induced Bronchospasm
A Study to Assess the Efficacy of Budesonide/Albuterol Metered-dose Inhaler (BDA MDI/PT027) on Exercise-induced Bronchoconstriction in Adults and Adolescents With Asthma
This is a multicenter, randomized, double-blind, single-dose, placebo-controlled, 2-period, crossover study to evaluate the efficacy and safety of budesonide/albuterol metered-dose inhaler (BDA MDI/PT027) as compared with a…
- Trial name
- TYREE (NCT04234464)
- Testing
- Budesonide/albuterol sulfate metered-dose inhaler 160/180 μg
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Bond Avillion 2 Development LP
Asthma
Effect of a Component of Fish Oil on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma
Docosahexaenoic acid (DHA) is a component of fish oil that is known to support a healthy cardiovascular system, maintain brain function, reduce depression, and improve inflammatory diseases.
- Trial name
- NCT01200446
- Testing
- Docosahexaenoic Acid
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Indiana University
Asthma, Exercise-Induced
Montelukast in Exercise-Induced Bronchospasm - 2004 (0476-275)
The purpose of this study is to determine the effect of an approved medication being studied in support of a new approach in the prevention of exercise-induced asthma (a worsening of asthma caused by exercise, also known as…
- Trial name
- NCT00090142
- Testing
- Comparator: Montelukast
- Volunteers
- 62 people
- Sponsor
- Organon and Co
Asthma, Obesity
Can Diet- and Exercise-Induced Weight Loss Improve Asthma Control in Adults?
The goal of the study is to investigate the efficacy of an evidence-based weight loss intervention, on a background of quality health care, on asthma control among obese adults.
- Trial name
- NCT00901095
- Testing
- Lifestyle intervention
- Where
- 8 sites in United States
- Volunteers
- 330 people
- Sponsor
- Palo Alto Medical Foundation
Asthma, Exercise-Induced
Montelukast Compared With Placebo and Salmeterol in Exercise-Induced Bronchoconstriction (0476-316)
To determine the effect of an approved medication being studied in support of a new approach in the prevention of exercise-induced asthma (a worsening of asthma caused by exercise, also known as exercise-induced bronchospasm), in…
- Trial name
- NCT00245570
- Testing
- Comparator: Montelukast, Comparator: Salmeterol
- Volunteers
- 47 people
- Sponsor
- Organon and Co
Exercise Induced Asthma
A Prospective Study Measuring Exhaled Nitric Oxide in Exercise-Induced Asthma
Exercise induced bronchospasm (EIB), also known as exercise induced asthma (EIA) is a transient obstruction to airflow triggered by exertion.
- Trial name
- NCT01097954
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Winthrop University Hospital
Asthma
Crossover Study Comparing Fluticasone Furoate (FF)/Vilanterol (VI) Once Daily Versus Fluticasone Propionate (FP) Twice Daily in Subjects With Asthma and Exercise-Induced Bronchoconstriction (EIB)
This is a multicenter, randomized, double-blind, double-dummy, crossover study with two 2-week treatment periods separated by a 2-week wash-out period.
- Trial name
- NCT02730351
- Testing
- Fluticasone furoate/ Vilanterol 100 mcg/25 mcg, Fluticasone propionate 250 mcg
- Where
- 16 sites in United States, Canada
- Volunteers
- 75 people
- Sponsor
- GlaxoSmithKline
Sleep Apnea, Obstructive, Asthma, Exercise-Induced
Pulmonary Disorders During Exercise in Patients With Obstructive Sleep Apnea
Purposes: 1. To investigate whether patients with severe obstructive sleep apnea syndrome (OSAS) are at higher risk for exercised-induced bronchoconstriction (EIB) due to baseline airway inflammation compared with age, gender…
- Trial name
- NCT00916773
- Testing
- continuous positive airway pressure (CPAP)
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Exercise Induced Asthma
Mediator Release During Exercise-induced Bronchoconstriction
This study will compare the inflammatory response in induced vs inhibited exercise induced bronchoconstriction (EIB) in patients with a medical diagnosis of asthma/EIB.
- Trial name
- NCT03524053
- Testing
- Exercise induced bronchoconstriction, Inhibited EIB
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Brunel University
Asthma, Wheezing
Swiss Paediatric Airway Cohort
The Swiss Paediatric Airway Cohort (SPAC) is a national, prospective clinical cohort of children and adolescents who visit physicians in Switzerland for recurrent wheeze, cough, and exercise- or sleep-related respiratory…
- Conditions
- Asthma, Wheezing, Cough, Exercise Induced Bronchospasm
- Trial name
- SPAC (NCT03505216)
- Where
- 12 sites in Austria, Switzerland
- Volunteers
- 6,000 people
- Sponsor
- University of Bern
Asthma
Effect of Different Anti-Asthmatic Treatments on Lung Function and on Exercise-Induced Bronchoconstriction in Children With Asthma
The present study was conducted to determine the effects of four week treatment with budesonide, montelukast, budesonide with montelukast and budesonide with formoterol in children with atopic asthma on lung function: forced…
- Trial name
- NCT00490243
- Testing
- budesonide and montelukast, budesonide and formoterol, montelukast
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Lodz
Exercise-induced Asthma
Bronchial Inflammation and Hyperresponsiveness After Oil Supplementation
The purpose of this study is to investigate the bronchial inflammation and hyperresponsiveness after oil supplementation. Before and after oil supplementation the investigators measure decrease in lung function after…
- Trial name
- NCT02410096
- Testing
- Exercise challenge in a cold chamber, Methacholine challenge, Oil supplementation verum
- Where
- Germany
- Volunteers
- 73 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Asthma and/or Exercise Induced Bronchoconstriction, Ozone Air Pollution
Salbutamol Use in Ozone Air Pollution by People With Asthma and/or Exercise Induced Bronchoconstriction (EIB)
Salbutamol use is increased in areas with high levels of ozone pollution and the potential consequences of this are not well known.
- Trial name
- NCT05087693
- Testing
- Salbutamol, Ozone, Filtered Air
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University of British Columbia
Asthma, Exercise Induced
Role of Leukotrienes and Adenosine in Hyperpnea-induced Bronchospasm
This research is being conducted to help us better understand what causes exercise induced asthma. The investigators hypothesize that two types of chemicals, cysteinyl leukotrienes and adenosine, play an important role.
- Trial name
- NCT00710255
- Testing
- Hyperpnea challenge
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Vermont
Asthma, Exercise-Induced
Montelukast in Exercise-Induced Bronchospasm - 2003 (0476-270)
The purpose of this study is to determine the effect of an approved medication being studied in support of a new approach in the prevention of exercise-induced asthma (a worsening of asthma caused by exercise, also known as…
- Trial name
- NCT00092131
- Testing
- Comparator: Montelukast
- Volunteers
- 51 people
- Sponsor
- Organon and Co
Asthma
How Different Beta-2 Receptor Genotypes Affect an Asthmatic's Response to Regular Salmeterol Treatment
The purpose of the study is to find out how well a long-acting beta agonist like salmeterol works in people with different forms of the same gene.
- Trial name
- SECS (NCT00595361)
- Testing
- salmeterol
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Brigham and Women's Hospital
Asthma (Diagnosis)
Predictive Factors for a Positive Exercise Bronchial Hyperresponsiveness Test
Exertional dyspnea has a significant impact on a child's daily life. Current guidelines recommend performing an exercise challenge test to confirm or rule out exercise-induced bronchoconstriction (EIB).
- Trial name
- PredEIB (NCT07766460)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Asthma
Effect of Fish Oil and Vitamin C on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma
Combining fish oil and vitamin C supplementation will provide a greater anti-inflammatory effect against developing exercise-induced bronchoconstriction (EIB) than either nutritional supplement alone.
- Trial name
- NCT01057615
- Testing
- Fish Oil, Ascorbic Acid
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Indiana University