Clinical trials: Exercise Prehabilitation
Haematological Malignancy, Bone Marrow Transplant Complications
Nutrition and Metabolic Prehabilitation in HSCT Patients UK and ROI. BSBMT Multi-centre Survey.
To explore current practices of nutrition and metabolic screening, assessment and management prior to Haematopoietic Stem Cell Transplant (HSCT) in UK and ROI transplant centres.
- Conditions
- Haematological Malignancy, Bone Marrow Transplant Complications, Stem Cell Transplant Complications, Nutrition Aspect of Cancer
- Trial name
- NCT05352789
- Testing
- Non validated Survey
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Muscle Loss, Disuse Atrophy
Preventing Bed-rest Induced Muscle Loss in the Elderly
Episodes of inactivity due to hospitalisation, as short as 5 days, are associated with rapid muscle and strength loss in the elderly.
- Conditions
- Muscle Loss, Disuse Atrophy, Protein Metabolism, Prehabilitation
- Trial name
- NCT04422665
- Testing
- Resistance exercise
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Primary Biliary Cholangitis (PBC)
RELIEF: Multimodal Prehabilitation to Treat Fatigue in Patients With Primary Biliary Cholangitis
The implementation of a non-pharmacological multimodal intervention program-including physical exercise, nutritional counseling, and psychological support-is expected to improve fatigue in patients with primary biliary…
- Trial name
- RELIEF (NCT07161245)
- Testing
- Multimodal prehabilitation, standard of care
- Where
- Spain
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Osteoarthritis, Knee
Prehabilitation Using Aquatic Exercise
With aging population, total knee arthroplasty is performed with increasing frequency. Although the surgery is successful in general, significant number of patients suffers persistent pain and disability.
- Trial name
- NCT02773745
- Testing
- Aquatic Prehab
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
End Stage Liver Disease, Physical Activity
The Feasibility of a Prehabilitation Program in the Liver Transplant Population at Barnes-Jewish Hospital
The primary outcome of this study is to demonstrate the feasibility of a prehabilitation program at Barnes Jewish Hospital for liver transplant candidates.
- Trial name
- NCT02444273
- Testing
- Exercise
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Coronary Artery Bypass Grafting, Heart Valve Replacement
A Prehabilitation Program for Frail Patients Undergoing Cardiac Surgeries/Procedures
The purpose of this study is to develop and evaluate a frailty-specific prehabilitation program for patients awaiting cardiac surgeries/procedures.
- Conditions
- Coronary Artery Bypass Grafting, Heart Valve Replacement, Transcatheter Aortic Valve Implantation, Frailty
- Trial name
- PREHAB (NCT06323317)
- Testing
- Multi-component exercise programme, Structured preoperative education, Nutritional optimization
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Frail Elderly Syndrome
Home-based Prehabilitation for Elderly Patients
As a consequence of the increasing life expectancy hospitals are seeing a growing number of elderly patients undergoing elective surgery.
- Trial name
- TRAilty (NCT03964363)
- Testing
- Unsupervised home-based physical prehabilitation
- Where
- 3 sites in Germany
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Vascular Surgery
POWER: PrehabilitatiOn Workshop and Mentored Exercise Programme in Patients Having Elective Aortic Aneurysm Repair
Protocol Short Title: POWER Study - PrehabilitatiOn Workshop and mentored Exercise programme in patients having elective aortic aneurysm Repair Population: Patients scheduled for elective repair of aortic aneurysm at St.
- Trial name
- POWER (NCT04169217)
- Testing
- Prehabilitation
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Cancer Surgery
Multimodal Prehabilitation in Cancer Surgery
The PROPOSE RCT is a two-arm randomized controlled trial that will be conducted to test the efficacy of a personalized, multidisciplinary pre-operative prehabilitation program (preventive prehabilitation) to reduce serious…
- Trial name
- PROPOSE-RCT (NCT06788834)
- Testing
- Multimodal prehabilitation Program
- Where
- 9 sites in Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Sarcopenia, Frailty
Oral Nutritional Supplementation With HMB Enhance Muscle Quality in Sarcopenic Surgical Patients
Aims: Clinical frailty severely impacts the physical, functional and physiological reserves necessary for the recovery after surgery.
- Trial name
- HEROS (NCT05344313)
- Testing
- Ensure Plus Advance
- Where
- Singapore
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Sengkang General Hospital
Locally Advanced Breast Cancer (LABC), Postoperative Inflammation
Preoperative Shoulder Exercises and Postoperative Inflammation, Pain, and Function After Modified Radical Mastectomy
This study evaluates whether preoperative shoulder range-of-motion exercises influence postoperative inflammatory response, pain, shoulder function, and quality of life in patients with locally advanced breast cancer undergoing…
- Conditions
- Locally Advanced Breast Cancer (LABC), Postoperative Inflammation, Prehabilitation
- Trial name
- NCT07420335
- Testing
- Preoperative shoulder exercise, Standard preoperative care
- Where
- Indonesia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Prehabilitation, Breast Cancer
Prehabilitation With Resistance-exercise Training for Breast Cancer Neoadjuvant Therapy
Breast cancer stands as the foremost cause of cancer-related deaths among women worldwide, with the highest incidence of any cancer type.
- Conditions
- Prehabilitation, Breast Cancer, Postmenopause, Resistance Training
- Trial name
- NEO STRONG (NCT06309290)
- Testing
- Prehabilitation with resistance-exercise training, Usual care program
- Where
- 2 sites in Chile
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Postoperative Complications, Breathing Exercises
Randomized-controlled Trial of Preoperative Inspiratory Muscle Training on Postoperative Complications
Rehabilitation strategies after abdominal surgery enhance recovery and improve outcome. A cornerstone of rehabilitation is respiratory physiotherapy with inspiratory muscle training to enhance pulmonary function.
- Conditions
- Postoperative Complications, Breathing Exercises, Preoperative Period
- Trial name
- INSPIRA (NCT04558151)
- Testing
- preoperative inspiratory muscle training
- Where
- Switzerland
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Cancer, Frailty
The Prehabilitation Study: Exercise Before Surgery to Improve Patient Function in People
The rapid aging of the population means that anesthesiologists care for elderly patients with increasing regularity. Although age is an independent predictor for adverse postoperative outcomes, significant outcome variation…
- Trial name
- NCT02934230
- Testing
- Prehabilitation Program
- Where
- Canada
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Healthy Adult Male and Female Volunteers, Intervention
Exploring Resistance Exercise Training Plus High-Intensity Interval Training (ReHIIT) as Cancer Prehabilitation
Colorectal cancer is the fourth most common cancer in the UK. Prehabilitation, including exercise, can improve recovery from surgery.
- Trial name
- ReHIIT_CON (NCT07313332)
- Testing
- ReHIIT Training Intervention
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Osteoarthritis
Prehabilitation Physical Activity in Persons With Osteoarthritis
Knee joint osteoarthritis (OA) reduces functional mobility and performance of daily tasks such as rising from a chair. Therefore interventions aimed at improving muscle strength and sit-to-stand task performance are very…
- Trial name
- PrehabOA (NCT02881463)
- Testing
- therapeutical exercises
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Tartu
Cancer
Does Prehabilitation Improve Exercise Performance and Insulin Resistance After Surgery for Oesophago-gastric Cancer?
The purpose of this study is to evaluate the effect of a multimodal pre-operative prehabilitation programme during neo-adjuvant therapy on cardiopulmonary exercise performance and insulin resistance prior to resection for…
- Trial name
- NCT02950324
- Testing
- Prehabilitation, Standard care
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Interval Training, Pre Operative Exercise
HIT in the Healthy Elderly Population
It is widely known that exercise improves general fitness and that fitter patients recover more easily from illness and surgery.
- Conditions
- Interval Training, Pre Operative Exercise, Prehabilitation, Elderly
- Trial name
- HIT (NCT02167191)
- Testing
- HIT
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nottingham