Clinical trials: Exercise Response, open to volunteers
Diabetes
Body Composition, Fitness, and Thermoregulation in Young Boys With Type I Diabetes vs. Healthy Soccer Players
The study aims to assess differences in body composition, exercise capacity, and thermoregulation between young soccer players with type 1 diabetes and their healthy peers.
- Trial name
- BCFTYR (NCT06676878)
- Testing
- Incremental exercise
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Paweł Korman
Bronchiectasis Adult, Healthy Controls Group - Age and Sex-matched
Cardiopulmonary Responses to 6-Minute Stepper Test in Bronchiectasis Versus Healthy Controls
Individuals with bronchiectasis exhibit productive cough and recurrent lung infections as well as reduced exercise capacity, physical activity level, and respiratory and peripheral muscle strength.
- Trial name
- NCT06631261
- Testing
- No intervention; Observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Respiratory Abnormality, Pulmonary
The Study Examined the Acute Effects of Wim Hof on Aerobic Training and Cardiodynamics.
Researchers will split the sixty healthy smokers in half. Thirty people will serve as a control group and will be asked to walk or jog at a controlled pace for twelve minutes as part of an aerobic exercise program.
- Conditions
- Respiratory Abnormality, Pulmonary, Exercise Training
- Trial name
- NCT07399119
- Testing
- aerobic exercise where it included walking/ jogging with a controlled speed by the participant, Wim Hof Breathing Method
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Cairo University
Breast Neoplasm Malignant Female, Exercise
Step Count and Treatment Response in Neoadjuvant Breast Cancer
This prospective multicenter observational study (NEOBRE-STEP) investigates the impact of daily step counts, measured by Huawei Fit 2 smartwatches, on treatment response in patients with non-metastatic Human Epidermal Growth…
- Conditions
- Breast Neoplasm Malignant Female, Exercise, Breast Cancer Females, Wearable Technology
- Trial name
- NEOBRE-STEP (NCT07162675)
- Testing
- Huawei Fit 2 Smartwatch
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Ankara Etlik City Hospital
Exercise Performance
U-LABA/ICS Effects on Exercise Performance, Vilanterol
The purpose of the project is to investigate exercise performance in humans following bronchodilation induced by acute inhalation of beta2-agonist vilanterol + fluticasone furoate
- Trial name
- NCT06066606
- Testing
- Vilanterol and Fluticasone Furoate (low dose), Vilanterol and Fluticasone Furoate (high dose)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Burns
Response of Muscle Mechanical Properties to Early Multi-angles Isometric Exercises in Acute Burn Patients
This study will be conducted to investigate the effect of early multi-angle isometric exercise on muscle properties in post-burn patients.
- Trial name
- ABP (NCT07832955)
- Testing
- isometric exercise program, conventional physical therapy
- Volunteers
- 40 people
- Sponsor
- Cairo University
Chronic Obstructive Pulmonary Disease (COPD)
Acute Effects of Inspiratory Muscle Training on Peripheral Muscle Metabolism and Autonomic Response in COPD Patients
The study will evaluate the acute effects of inspiratory muscle training (IMT) on peripheral muscle metabolism and autonomic response in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT06827379
- Testing
- IMT-S (strength), IMT-R (resistance)
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of Paraíba
Weight Gain, Weight Loss
Nutritional Responses to Acute Exercise Performed on the LipoxMax in Obese Adolescents
Primarily over the past 20 years, it has been shown that physical activity not only leads to energy expenditure but can also indirectly influence energy intake and feelings of hunger in both lean and obese adults, suggesting that…
- Conditions
- Weight Gain, Weight Loss, Eating Attitudes, Obese Adolescents
- Trial name
- LipoxAPP (NCT07844330)
- Testing
- The participants in this study are adolescents with obesity (with a Body Mass Index above the 95th percentile on international growth charts)
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Centre Hospitalier Emile Roux
HIV Infections
Cardiovascular Responses to Exercise in People Living With HIV/AIDS: Effects of Exercise Training
Patients living with HIV (PLWHIV) have compromised muscle metaboreflex, which can cause exercise intolerance. This randomized controlled clinical trial will verify the effects of regular exercise on autonomic and hemodynamic…
- Trial name
- NCT04512456
- Testing
- Exercise training
- Where
- Brazil
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cardiologia de Laranjeiras
Heat Stress, Physiological Stress
Impact of Indoor Overheating on Physiological Strain in Children
Communities worldwide are experiencing increasing heat extremes that challenge the limits of human thermoregulation, particularly among vulnerable populations such as children.
- Conditions
- Heat Stress, Physiological Stress, Cognitive Change
- Trial name
- NCT07261202
- Testing
- Simulated exposure to indoor overheating
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Prediabetes
Mechanism Study of Metabolic Response and Health Benefit Induced by Exercise
This study is a single-arm, self-control, single-center study to investigate the mechanism under exercise inducing metabolic response and health benefit.
- Trial name
- NCT06633653
- Testing
- exercise intervention
- Volunteers
- 40 people
- Sponsor
- Shanghai Zhongshan Hospital
Obesity/therapy
Remote Approaches for Optimizing Weight Loss (Elevate Weight Loss Trial)
The purpose of this trial is to compare two delivery formats for weight loss (automated online program vs. group-based videoconference program) and to examine the added effect of individual coaching (vs.
- Trial name
- NCT06875622
- Testing
- Automated online weight loss program, Individual coaching, Group-based, videoconference-delivered weight loss
- Where
- United States
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Chronic Low Back Pain (CLBP)
Neuroimmune Responses to Exercise in Chronic Back Pain
The goal of this mechanistic clinical trial is to learn how physical exercise affects the body and brain in people with chronic low back pain.
- Trial name
- eCLBP (NCT07497425)
- Testing
- Physical Exercise
- Where
- Canada
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- McGill University
Sound Exposure, Exercise Performance
Effect of High-Level Headphone Sound Exposure on Exercise Responses in Young Healthy Individuals
This study will investigate the effect of high-level headphone sound exposure on cardiorespiratory responses and perceived exertion during a submaximal treadmill exercise test in young healthy individuals.
- Trial name
- NCT07556666
- Testing
- High-Level Headphone Sound Exposure, No-Sound Headphone Condition
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Breast Cancer Lymphedema, Survivorship
Lymphatic Response to Resistance Exercise in Breast Cancer Survivors
The objective of this study is 1) to study the acute and chronic effect of resistance therapeutic physical exercise (RTPE) in the prevention of breast cancer-related lymphedema (BCRL) in breast cancer survivors at risk using…
- Conditions
- Breast Cancer Lymphedema, Survivorship, Lymphedema of Upper Limb
- Trial name
- LinfoGYM (NCT06113627)
- Testing
- Resistance Therapeutic Exercise
- Where
- Spain
- Volunteers
- 170 people
- Sponsor
- University of Malaga
Athletic Performance, Dietary Supplement
The Effects of Acute Nitrate and Caffeine Co-ingestion on Discipline-Specific Exercise Performance.
The purpose of this study is to investigate the acute, separate, and combined ergogenic effects of dietary nitrate (beetroot juice, BJ) and caffeine (CAF) supplementation on discipline-specific athletic performance.
- Conditions
- Athletic Performance, Dietary Supplement, Iron Status
- Trial name
- NCT07748416
- Testing
- Caffeine, Dietary Nitrate (Beetroot Juice)
- Where
- Poland
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Behavior
Acute Effects of Mat Pilates on Blood Pressure Response to Mental Stress in Higher Education Teachers
This study will investigate the acute effects of a moderate-intensity Mat Pilates session on blood pressure responses to mental stress in higher education teachers.
- Trial name
- NCT07872592
- Testing
- Acute Exercise, Control
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Federal University of Mato Grosso
Arthritis, Rheumatoid Arthritis (RA)
Dose Response of Exercise for Arthritis Management
The purpose of the study is to see examine the effects of 3 different levels of physical activity (45 minutes/week, 90 minutes/week, or 150 minutes/week) on arthritis symptoms.
- Conditions
- Arthritis, Rheumatoid Arthritis (RA), Gout, Fibromyalgia (FM)
- Trial name
- DREAM (NCT06880653)
- Testing
- DREAM Adaptive Intervention
- Where
- United States
- Volunteers
- 285 people
- Sponsor
- University of South Carolina
Breast Neoplasms, Breast Cancer
IRELAND Trial: A Translational Biomarker and Exercise Study During Neoadjuvant Breast Cancer Therapy
The goal of this clinical trial is to learn whether a physiotherapy-led exercise programme delivered during treatment before surgery (neoadjuvant therapy) for breast cancer can improve physical fitness, quality of life, and how…
- Trial name
- IRELAND (NCT07799337)
- Testing
- Physiotherapist-Led Personalised Adaptive Exercise Programme
- Volunteers
- 250 people
- Sponsor
- National University of Ireland, Galway, Ireland
Gastrointestinal Cancer
A Study on the Effects of Exercise on Side Effects From Treatment for Gastrointestinal Cancers
The purpose of this study is to find the level of aerobic exercise (AT) that is practical, is safe, and has positive effects on the body that may reduce the side effects of therapy.
- Trial name
- NCT05789485
- Testing
- structured treadmill walking
- Where
- 8 sites in United States
- Volunteers
- 216 people
- Sponsor
- Memorial Sloan Kettering Cancer Center