Clinical trials: Exercise Sensitivity
Insulin Sensitivity, Physical Activity
METAPREDICT: Developing Predictors of the Health Benefits of Exercise for Individuals
Physical activity is a powerful lifestyle factor that on average reduces risk for development of diabetes and cardiovascular disease.
- Trial name
- METAPREDICT (NCT01920659)
- Testing
- High Intensity Training (HIT), REHIT
- Where
- United Kingdom
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Insulin Sensitivity
mTOR as Mediator of Insulin Sensitivity Study
The study investigates the role of mTOR in mediating enhancement of muscle insulin sensitivity following a single bout of exercise.
- Trial name
- NCT05233722
- Testing
- Exercise, Insulin infusion, Rapamycin
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Obesity, Insulin Resistance
Effects of Exercise Training Intensity on Fitness and Insulin Sensitivity in African Americans
African Americans are at a substantially greater type 2 diabetes risk compared to Caucasians; however, very little data are available on the effects of exercise training on type 2 diabetes risk factors in at risk African…
- Conditions
- Obesity, Insulin Resistance, Sedentary Lifestyle
- Trial name
- HI-PACE (NCT02892331)
- Testing
- Moderate intensity exercise training (MOD-INT), High Intensity exercise training (HI-INT)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Resistance Exercise, Physical Inactivity
Modified Breath Test to Determine Anabolic Sensitivity Across Physical Activity States
Developing tools to detect when our bodies are more resistant towards protein synthesis is valuable for identification of when someone may be at risk of losing body or muscle mass such as with aging or certain diseases.
- Conditions
- Resistance Exercise, Physical Inactivity, Amino Acids, Dietary Protein
- Trial name
- BTLP (NCT06209424)
- Testing
- Habitual Activity, Step-Reduction, Resistance Exercise
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Neck Pain, Healthy
The Effect of Exercise on Pain Sensitivity in a Population With Ongoing Neck Pain Compared to Healthy Controls
This study investigates the effect of exercise on pain sensitivity in ongoing neck pain patients compared to a healthy control group.
- Trial name
- NCT03992495
- Testing
- Exercise
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Obesity
Health Benefits of Chronic vs. Acute Exercise in Overweight Adults
Compare the effects of single session of exercise vs. chronic exercise training on key risk factors associated with Metabolic Syndrome (e.g., glucose tolerance, blood lipid profile, and blood pressure) in overweight adults.
- Trial name
- NCT01452087
- Testing
- Exercise
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Insomnia, Healthy Adult
The Impact of Insomnia on Pain Sensitivity and the Trajectory of Exercise-induced Muscular Pain
Sleep is a critical determinant of physiological recovery and pain regulation. Growing evidence suggests that sleep disruption directly heightens central and peripheral pain sensitivity to sensory stimuli (e.g., mechanical…
- Conditions
- Insomnia, Healthy Adult, Musculoskeletal Pain, Pain Sensitivity
- Trial name
- NCT07827664
- Testing
- Eccentric exercise
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Insulin Resistance, Insulin Sensitivity
Mechanism of Insulin-Resistant in Lean Non-Diabetics
The study is designed to test the following primary hypothesis: Aerobic exercise training will improve insulin sensitivity in insulin resistant subjects through changes in the major cellular signaling pathways and and/or their…
- Conditions
- Insulin Resistance, Insulin Sensitivity, Type 2 Diabetes
- Trial name
- NCT00970099
- Testing
- exercise, Non exercise
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Neuromuscular Fatigue, Load-velocity Variables
Sensitivity of Load-Velocity Measures for Detecting Fatigue During Smith-Machine Squats
The purpose of this study is to determine whether load-velocity (L-V) relationship variables (L0, v0, and Aline) are sensitive indicators of fatigue produced by different squat fatigue protocols.
- Trial name
- SLV (NCT07307963)
- Testing
- Control Protocol (No Training), Moderate-fatigue, High-fatigue
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Exercise-induced Bronchospasm
Mechanisms of Exercise-induced Bronchospasm
The term exercise-induced bronchospasm (EIB) describes acute, transient airway narrowing that occurs during, and most often after, exercise.
- Trial name
- NCT00701025
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Asthma, Exercise-Induced
The Effect of Physical Exercise in a Cold Air Environment on Normal Volunteers and Asthmatic Patients
The purpose of the study is to compare airway physiologic reactions to physical exercise in a cold air environment (-5°C, 60% relative humidity) between normal volunteers and subjects with mild/moderate asthma.
- Trial name
- ALASCAIR1 (NCT03840044)
- Testing
- Cold air exercise test
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Diabetes Mellitus, Type 2
Exercise Training and Type 2 Diabetes
The purpose of this study is to assess whether 4-months of interval-walking exercise training improves glycemic control in individuals with type 2 diabetes mellitus.
- Trial name
- NCT01234155
- Testing
- Exercise Training - Interval Walking, Exercise - Continuous Walking
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cardiovascular Disease, Asthma
Effectiveness of Pollution Monitoring in Clinical Exercise Rehabilitation
The primary objective of EPIC-AIR is to evaluate the feasibility and potential effectiveness of integrating real-time air pollution monitoring into cardiac rehabilitation (CR) and pulmonary rehabilitation (PR) programmes via an…
- Conditions
- Cardiovascular Disease, Asthma, COPD, Interstitial Lung Disease Due to Systemic Disease
- Trial name
- EPIC-AIR (NCT07500948)
- Testing
- Progressive Walking Exercise Programme, Real-time air quality information and guidance
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Insulin Sensitivity
Insulin Sensitivity and Testosterone Response to Aerobic Exercise Versus Added Sugar Elimination in Polycystic Ovary Syndrome Women
the aim of this study is to investigate the effect of aerobic exercise versus the effect of added sugar elimination on the insulin sensitivity and testosterone levels in females with polycystic ovarian syndrome via measuring the…
- Trial name
- NCT07139275
- Testing
- aerobic exercise, added sugar elimination, aerobic exercise and added sugar elimination
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Body Weight
Metabolic and Bio-behavioral Effects of Following Recommendations in the Dietary Guidelines for Americans
This study, at the Western Human Nutrition Research Center (WHNRC), will focus on whether or not achieving and maintaining a healthy body weight is the most important health promoting recommendation of the Dietary Guidelines for…
- Trial name
- DGA4ME (NCT04293224)
- Testing
- DGA Mediterranean diet pattern, energy balance, DGA Mediterranean diet pattern, negative energy balance, TAD diet pattern, negative energy balance
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Insulin Sensitivity
The Importance of Insulin Action in the Brain for the Immune System During Physical Activity-Overweight
The goal of this clinical trial is to clarify the interaction of central insulin action and physical activity with the immune system. Therefore, participants will undergo bicycle spiroergometer tests.
- Trial name
- NCT07466173
- Testing
- Spiroergometer test with intranasal insulin spray
- Where
- Germany
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis
Skeletal Muscle Function in Interstitial Lung Disease
Dyspnea (i.e. breathlessness) and exercise intolerance are common symptoms for patients with interstitial lung disease (ILD), yet it is not known why.
- Conditions
- Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Hypersensitivity Pneumonitis, Scleroderma
- Trial name
- NCT03800017
- Testing
- Hyperoxia
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Asthma, Rehabilitation
Effectiveness of the Rehabilitation Nursing Consultation for People With Asthma on Symptom Control and Quality of Life
Introduction Asthma is a chronic inflammatory disease of the respiratory airways and is considered a Public Health problem, which lacks a personalized multidisciplinary intervention, to allow the user to develop mastery in the…
- Conditions
- Asthma, Rehabilitation, Breathing, Mouth, Nursing Caries
- Trial name
- NCT06061497
- Testing
- Abdomino-diaphragmatic breathing, Usual Care
- Where
- Portugal
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- ACES Entre Douro e Vouga II - Aveiro Norte
Tension-Type Headache
Effectiveness of Deep Cervical Flexor Muscle Exercises in Patients With Tension-Type Headache
The aim of this study is to evaluate the effects of deep cervical flexor muscle exercises on pain, spinal posture, and sensory sensitivity in patients with tension-type headaches.
- Trial name
- Single-Blind (NCT06632808)
- Testing
- Exercise
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Branched-chain Amino Acid Metabolism, Insulin Sensitivity
Regulation of Branched-chain Amino Acid Metabolism in Pre-Diabetes
Elevated circulating levels of certain amino acids (the building blocks of protein) are strongly associated with insulin resistance.
- Trial name
- BCAAM-PD (NCT01786941)
- Testing
- Pre-Diabetes Group - 6-mo Aerobic and Resistance combined exercise training, GBP Group - Non-diabetics intending to undergo Gastric Bypass surgery
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Duke University