Clinical trials: Exercise Sensitivity
Insulin Sensitivity, Glucose Intolerance
Effects of Progressive Negative Energy Balance on Glucose Tolerance, Insulin Sensitivity, and Beta-cell Function
Type 2 diabetes results from a combination of peripheral insulin resistance and beta-cell dysfunction, and manifests as fasting and postprandial hyperglycemia.
- Conditions
- Insulin Sensitivity, Glucose Intolerance, Insulin Resistance, Energy Supply; Deficiency
- Trial name
- NCT03264001
- Testing
- Negative energy balance
- Where
- Singapore
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Pre-diabetes, Overweight and Obesity
Timing Exercise Training as Strategy to Improve Insulin Sensitivity and Substrate Metabolism in Men and Woman With Pre-diabetes
n a retrospective analysis of an exercise training program performed either in the morning or afternoon, we found that the afternoon training group improved their peripheral insulin sensitivity and fasting plasma glucose levels…
- Trial name
- Timed Training (NCT06014684)
- Testing
- Timing of exercise
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Insulin Resistance
Mechanisms of Insulin Resistance and Exercise in South Asians
This study determines the effect of aerobic and resistance exercise training on whole-body and skeletal muscle insulin sensitivity in south Asians and evaluate the mechanisms which contribute to improvements in insulin…
- Trial name
- NCT04007926
- Testing
- Aerobic exercise programme, Resistance exercise programme
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Bronchospasm, Exercise-Induced
Effectiveness of Ipratropium Bromide in Preventing Exercise-induced Bronchoconstriction in Athletes
This will be a double-blind placebo-controlled study in which we plan to study 40 competitive endurance athletes. We will conduct an exercise test to evaluate maximal oxygen uptake and 2 exercise challenge tests to provoke EIA.
- Trial name
- STAMINA (NCT01691079)
- Testing
- ipratropium bromide
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Osteoarthritis, Knee, Pain
Biologic Mechanisms for Pain Variation After Physical Activity in Osteoarthritis
Osteoarthritis (OA) in the knee is characterized by chronic inflammatory pain that is not necessarily related to the amount of joint damage.
- Conditions
- Osteoarthritis, Knee, Pain, Physical Activity, Mitochondrial Pathology
- Trial name
- NCT03344913
- Testing
- Walking
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Pain, Physical Activity
Influence of Expectations on Change in Pain Perception After a 3 Min Wallsquat Exercise.
The purpose of this study is to investigate how expectations induced by information given prior to exercise influence the magnitude of exercise-induced hypoalgesia after a 3 min wallsquat exercise in healthy subjects.
- Trial name
- NCT03678662
- Testing
- Hypoalgesia expectation, Hyperalgesia expectation, Neutral
- Where
- Denmark
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Obesity, Insulin Resistance
Race, Menopause and Metabolism After Exercise and Diet
The purpose of this study is to test the hypotheses that there are ethnic and genetic differences in the mechanisms and magnitude by which hypocaloric weight loss and aerobic exercise affect body composition, glucose, lipid…
- Conditions
- Obesity, Insulin Resistance, Sedentary Lifestyle
- Trial name
- NCT00882141
- Testing
- Diet modification, Aerobic exercise
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Obesity, Obesity; Endocrine
Acute and Chronic Metabolic Flexibility in Individuals Living With Obesity: The i-FLEX Study
Regular exercise is a cornerstone in the prevention and the management of cardio-metabolic risk factors. Some of the beneficial effect of exercise training occurs through metabolic flexibility' enhancement.
- Conditions
- Obesity, Obesity; Endocrine, Insulin Sensitivity, Exercise
- Trial name
- i-FLEX (NCT03527446)
- Testing
- Sprint Interval Training
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of New Brunswick