Clinical trials: Exercise Sensitivity
Inflammation, Insulin Sensitivity
Sugar-sweetened Beverages Influence Benefits of Exercise in Overweight Adults
The objective of this study was to determine how metabolic and inflammatory effects of physical exercise in overweight individuals are altered when sugar-sweetened beverages (SSB) are consumed after physical exercise.
- Trial name
- NCT03576703
- Testing
- Exercise with and without SSB ingestion
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Montana State University
Insulin Sensitivity
The Importance of Insulin Action in the Brain for the Immune System During Physical Activity
The goal of this clinical trial is to clarify the interaction of central insulin action and physical activity with the immune system. Therefore, participants will undergo bicycle spiroergometer tests.
- Trial name
- NCT06552130
- Testing
- Spiroergometer test with intranasal insulin spray
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Asthma
How Different Beta-2 Receptor Genotypes Affect an Asthmatic's Response to Regular Salmeterol Treatment
The purpose of the study is to find out how well a long-acting beta agonist like salmeterol works in people with different forms of the same gene.
- Trial name
- SECS (NCT00595361)
- Testing
- salmeterol
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Brigham and Women's Hospital
Anxiety, Depression Disorders
ABC School Intervention Among Ugandan Adolescents
Schools can be pivotal in addressing mental health challenges, especially in low-income settings like Uganda. This pilot cluster-randomized trial examines the impact of a culturally sensitive Act-Belong-Commit (ACT) intervention…
- Trial name
- NCT06957925
- Testing
- educational
- Where
- 2 sites in Uganda
- Volunteers
- 2,598 people
- Sponsor
- KU Leuven
Asthma
A Randomized Trial of Changing Exercise and Physical Activity Behavior in Asthma Patients
The primary objective of this randomized trial is to evaluate a novel intervention of induced positive affect and induced self-affirmation to increase physical activity in patients with asthma.
- Trial name
- NCT00195117
- Testing
- Intervention Group
- Where
- United States
- Volunteers
- 258 people
- Sponsor
- Weill Medical College of Cornell University
Asthma
A Study to Evaluate the Effect of Dupilumab on Exercise Capacity in Adult Patients With Asthma
The primary objective of the study is to demonstrate that dupilumab treatment improves exercise capacity in patients with moderate-to-severe asthma.
- Trial name
- NCT04203797
- Testing
- dupilumab
- Where
- 30 sites in United States, France and 3 more
- Volunteers
- 40 people
- Sponsor
- Regeneron Pharmaceuticals
Insulin Sensitivity
Effect of Acute Bout of Exercise on Levels of PAHSA
Exercise represents an important tool in the prevention and treatment of metabolic disorders associated with obesity and aging, such as type 2 diabetes and cardiovascular disease.
- Trial name
- ETAPA (NCT05572905)
- Testing
- Exercise, Fasting control
- Where
- Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lenka Rossmeislova
Asthma
EFFORT Asthma: Effects of Diet and Exercise in Asthma
This project aims to study the effects of lifestyle changes on asthma and systemic inflammation in a randomized clinical trial of diet and exercise.
- Trial name
- EFFORT (NCT02355964)
- Testing
- Exercise, Diet
- Where
- Denmark
- Volunteers
- 149 people
- Sponsor
- University of Copenhagen
Breathing Techniques, Asthma Control Level
Effects of Buteyko Breathing Exercise in Children With Uncontrolled Asthma
This randomized controlled trial study aimed to measure the effectiveness of the combination of 4-weeks Buteyko breathing exercises and pharmacological therapy compared with pharmacological therapy alone in children with…
- Conditions
- Breathing Techniques, Asthma Control Level, Asthma in Children, Asthma Patients
- Trial name
- NCT07025616
- Testing
- Buteyko, Asthma reliever and controller
- Where
- Indonesia
- Volunteers
- 74 people
- Sponsor
- Ivan Sofian Wibowo
Asthma (Diagnosis), Breathing Exercises
Comparative Effect of Box Breathing And Buteyko Breathing on Pulmonary Functions in Asthma
The aim of this study was to evaluate the Effectiveness of Box Breathing Technique and Buteyko breathing techniques in patients with Asthma, using both Clinical Pulmonary tests as well as Patient reported outcomes.
- Trial name
- NCT07140458
- Testing
- Buteyko Breathing, Box breathing
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Asthma
Using Exercise-testing to Explore Patient Differences in Severe Asthma
The goal of this observational pilot study is to use exercise-testing to assess patients with severe asthma who have high levels of breathlessness and compare them to other groups of patients with low levels of breathlessness.
- Trial name
- NCT05733143
- Testing
- cardiopulmonary exercise stress test (CPEST)
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- Queen's University, Belfast
Exercise Sensitivity, Introceptive Exposure
Behavioral Exposure for Introceptive Tolerance RCT
Behavioral Exposure for Interoceptive Tolerance (BE-FIT) is a mechanism-informed behavioral intervention to target exercise anxiety.
- Conditions
- Exercise Sensitivity, Introceptive Exposure, Anxiety, Cardiac Rehabilitation
- Trial name
- BE-FIT (NCT05398276)
- Testing
- Behavioral Exposure For Introceptive Tolerance, Health Education Control
- Where
- 3 sites in United States
- Volunteers
- 146 people
- Sponsor
- Rutgers, The State University of New Jersey
Type 2 Diabetes Mellitus
Acute Effect of Phototherapy With Light Emitting Diode (LED) on Muscle and Pulmonary Oxygen Consumption on Diabetes Mellitus
The purpose of this study is to determine the phototherapy may be adjuvant to exercise to improve muscular efficiency and increase aerobic capacity.
- Trial name
- NCT01889784
- Testing
- Phototherapy through light emitting diode (LED) - 150J, Phototherapy through light emitting diode (LED) - 300J
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aparecida Maria Catai
Ectopic Lipids, Insulin Sensitivity
The Effect of Dietary Fat Load and Physical Exercise on the Flexibility and Partitioning of Ectopic Lipids.
This study aims at assessing the effect of standardized dietary fat load and short-term aerobic exercise on systemic lipolysis, flexibility and partitioning of ectopic fat stores (intramyocellular = IMCL, intrahepatocellular =…
- Conditions
- Ectopic Lipids, Insulin Sensitivity, Aerobic Exercise, Fat Load
- Trial name
- NCT01467193
- Testing
- Fat diet, 2h standardized aerobic exercise
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Insulin Sensitivity/Resistance
Protective Effect of Exercise on Acute High-fat Overfeeding
Metabolic flexibility is the ability to switch rapidly from one substrate (i.e. fuel source) to another (e.g. fats to carbohydrates) in response to ingested foods.
- Trial name
- HFDEXC (NCT07633704)
- Testing
- High Fat Overfeeding, High Fat Overfeeding + Exercise
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- George Washington University
Insulin Sensitivity
Ischemia-reperfusion Exercise Study
The study investigates the relationship between activation of AMP-activated protein kinase (AMPK) in human skeletal muscle and the subsequent improvement in muscle insulin sensitivity for the stimulation of glucose uptake.
- Trial name
- NCT04872426
- Testing
- Exercise, insulin infusion
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Diabetes Mellitus, Obesity
Exercise to Reduce Obesity in Spinal Cord Injury
The purpose of this proposal was to evaluate and compare the health benefits of using upper extremity exercise versus functional electrical stimulation for lower extremity exercise.
- Conditions
- Diabetes Mellitus, Obesity, Paraplegia, Quadriplegia
- Trial name
- NCT00270855
- Testing
- Arm Crank Ergometry, FES Cycle Ergometer
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Office of Research and Development
Allergic Asthma
The Impact of Breath Exercises by Telemedicine in Patients Aged 8-18 Years With a Diagnosis of Asthma
The goal of this randomized, placebo controlled study is to evaluate the effect of respiratory exercises on asthma attack frequency, symptom and medication scores and quality of life of children with a diagnosis of asthma.
- Trial name
- PHASTER (NCT05749237)
- Testing
- respiratory exercises, relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University - Cerrahpasa
Coronary Artery Disease
Impact of Coronary Artery Bypass Graft (CABG) Surgery on Skeletal Muscle Mass and Insulin Sensitivity, Followed by Exercise Intervention
In this study, the investigators want to examine the impact of coronary artery bypass graft (CABG) surgery on skeletal muscle mass, muscle metabolism, and insulin sensitivity in 90 subjects.
- Trial name
- NCT01333839
- Testing
- exercise training
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Hasselt University
Non Alcoholic Fatty Liver Disease
The Effect of Exercise Intervention on Insulin Resistance in Non-alcoholic Fatty Liver Disease (NAFLD)
This project examines the effects of a 4 month structured exercise intervention program in patients with non-alcoholic fatty liver disease (NAFLD).
- Trial name
- NCT01834300
- Testing
- Unsupervised exercise training, Supervised exercise training
- Where
- 7 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Liverpool