Clinical trials: Exercise-Induced Muscle Damage
Healthy
Evaluation of the Effects of a Novel Dietary Microalgae Based Ingredient on Muscle Recovery and Endurance Capacity
The purpose of this investigation is to examine the effects of consuming a new dietary microalgae based supplement vs. placebo on neuromuscular function, energy utilization, soreness, perceptual wellness, swelling, and markers of…
- Trial name
- PORPHY-ONE (NCT05760742)
- Testing
- MicAlgae
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Microphyt
Becker Muscular Dystrophy, McArdle Disease
Fast Troponin as a Biomarker to Assess Exercise-induced Muscle Damage in Muscle Diseases
The purpose of the study is to explore the biomarker Fast Troponins response to exercise in patients with Becker muscular dystrophy, Limb-girdle muscular dystrophy and McArdle disease
- Conditions
- Becker Muscular Dystrophy, McArdle Disease, Limb-Girdle Muscular Dystrophy Type 2
- Trial name
- NCT04349566
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mads Peter Godtfeldt Stemmerik
Exercise Induced Muscle Damage
Exercise Induced Muscle Damage Post Dance and Sprint Specific Exercise in Females
There is a paucity of studies investigating exercise-induced muscle damage (EIMD) in females and only one in response to dance-type exercise.
- Trial name
- NCT03284450
- Testing
- DPFT, SSRS
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Healthy Volunteer
Evaluation of Astaxanthin Properties on Anti-fatigue
Ten young, healthy, physically active male college students were crossed over for AST or placebo supplements randomized into placebo or AST trials and orally consumed placebo or AST (28 mg/d) supplements for four days.
- Trial name
- NCT06593535
- Testing
- Astaxanthin (AST trial)
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Muscle Damage, Inflammation
Branched-chain Amino Acids Supplementation and Resistance Exercise-induced Muscle Damage and Inflammation
This study aims to evaluate the effects of branched-chain amino acids (BCAA) supplementation on resistance exercise-induced muscle damage and inflammation.
- Trial name
- NCT01305018
- Testing
- BCAA, Leucine
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Inflammatory Response, Metabolic Disturbance
Astaxanthin, Exercise Inflammation, Skin Health
Vigorous exercise can stress the body. Consuming special types of diet supplements may help the body recover better from exercise.
- Conditions
- Inflammatory Response, Metabolic Disturbance, Immune Suppression
- Trial name
- NCT05409092
- Testing
- Astaxanthin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Exercise Induced Muscle Damage
Effect of Far Infrared Reflecting Sleepwear on Recovery and Sleep
Far infrared light (FIR, 5.6-1000 µm) penetrates our skin and reaches the underlying tissue up to 4 cm and promotes widening of the blood vessels (vasodilation).
- Trial name
- NCT04273789
- Testing
- Far infrared reflecting sleepwear
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Muscle Recovery
Investigating the Efficacy of Low or High Dose Tart Cherry on Recovery From Exercise Induced Muscle Damage and Establishing Its Molecular Mechanisms of Action
To determine the dose-response effects of 10-day tart cherry product consumption (0, 30 ml, and 60 ml) on knee extensor isometric strength 24-h and 48-h after muscle damaging exercise and to elucidate the mechanisms of action for…
- Trial name
- NCT04725149
- Testing
- 500 ml base solution, 500 ml containing 30 ml tart cherry concentrate diluted with water and base solution, 500 ml containing 60 ml tart cherry concentrate diluted with water only
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Delayed-Onset Muscle Soreness (DOMS), Exercise-induced Muscle Damage
TENS Versus Foam Rolling for Muscle Recovery After Eccentric Exercise in Elite Female Volleyball Players
Purpose: This study compared two recovery methods-transcutaneous electrical nerve stimulation (TENS) and foam rolling (FR)-for muscle recovery after intense exercise in elite female volleyball players.
- Conditions
- Delayed-Onset Muscle Soreness (DOMS), Exercise-induced Muscle Damage, Muscle Recovery, Athletic Injuries
- Trial name
- TENS-FR-VB (NCT07438197)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), Foam Rolling (FR)
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Insomnia, Healthy Adult
The Effect of Different rTMS Interventions on Acute Experimental Muscular Pain in Individuals Comorbid With Insomnia
Insomnia exacerbates pain sensitivity and impairs physiological recovery from acute musculoskeletal pain. Repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising non-invasive neuromodulation intervention to…
- Conditions
- Insomnia, Healthy Adult, Exercise Induced Muscle Damage, Pain Sensitivity
- Trial name
- NCT07827677
- Testing
- Repetitive transcranial magnetic stimulation (rTMS) on L M1, Repetitive transcranial magnetic stimulation (rTMS) on R DLPFC
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Oxidative Stress, Healthy
A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance
This is a prospective, randomized, placebo controlled, double-blind study to assess the effects of a postbiotic blend on exercise induced oxidative stress markers and exercise performance in healthy adult.
- Conditions
- Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness
- Trial name
- PBE (NCT06795425)
- Testing
- Postbiotic Active Lifestyle Blend
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Wrist Injuries
Effects of Low Level Laser Therapy On Exercise Induced Muscle Damage in Wrist Flexors Of Untrained Young Adults
The main aim of the current study is to investigate the effects of Low-level Laser Therapy on exercise-induced muscle damage of wrist flexors in untrained young adults.
- Trial name
- NCT04842669
- Testing
- low level laser therapy, Conservative treatment
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Exercise-induced Muscle Soreness
Effects of Traumeel®S Tablets on Recovery and Inflammatory Immune Response After Repeated Bouts of Exercise
To investigate and compare the effects of Traumeel®S tablets versus placebo on recovery and inflammatory immune response over a period of 72 hours after a second bout of strenuous concentric exercise on bicycle (exercise #2).
- Trial name
- NCT01921777
- Testing
- Traumeel
- Where
- Germany
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. med. Frank Christoph Mooren
Exercise-Induced Muscle Damage, Rhabdomyolysis
DOES LOWER BODY PLYOMETRICS CAUSE RHABDOMYOLYSIS IN FEMALE VOLLEYBALL PLAYERS-AN EXPERIMENTAL STUDY
Eight-week interventional study to evaluate whether lower-body plyometric training alters serum creatine phosphokinase (CPK) and creatinine levels in female collegiate volleyball players.
- Conditions
- Exercise-Induced Muscle Damage, Rhabdomyolysis, Athletes
- Trial name
- NCT07352319
- Testing
- plyometric program
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Muscle Injury, Muscle Soreness
Effects of Wobenzym® Plus in Healthy, Sportive People After Eccentric Exercise
The aim of the current study is to investigate the therapeutic effect and especially the mode of action of Wobenzym® plus, an anti-inflammatory drug containing proteolytic enzymes, on exercise induced muscle damage (eiMD) and…
- Conditions
- Muscle Injury, Muscle Soreness, Exercise Induced Muscle Damage
- Trial name
- 2012-005003-40 (NCT01845558)
- Testing
- Wobenzym® plus
- Where
- Germany
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Mucos Pharma GmbH & Co. KG
Delayed Onset Muscle Soreness, Exercise-induced Muscle Damage
Antioxidant Supplementation and Muscle Recovery From DOMS in Trained Women
This randomized, placebo-controlled, parallel-group trial investigated the effects of combined antioxidant and anti-inflammatory supplementation on delayed onset muscle soreness (DOMS) recovery in trained women.
- Conditions
- Delayed Onset Muscle Soreness, Exercise-induced Muscle Damage, Muscle Recovery
- Trial name
- NCT07877441
- Testing
- Creatine Monohydrate, Omega 3 FA (Fish Oil), N-Acetyl Cysteine (NAC)
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Antonio Molina Lopez
Exercise-induced Muscle Damage, Oxidative Stress
New Zealand Blackcurrant and Recovery in Elite Taekwondo
This randomized, double-blind, placebo-controlled trial evaluated the effects of short-term supplementation with anthocyanin-rich New Zealand blackcurrant (NZBC) extract on exercise-induced muscle damage, oxidative stress…
- Conditions
- Exercise-induced Muscle Damage, Oxidative Stress, Inflammation, Recovery After Exercise
- Trial name
- NZBC-TAE (NCT07828444)
- Testing
- New Zealand Blackcurrant Extract (CurraNZ®)
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Muscle Weakness, Muscle Damage
Acute Physiological Responses to Twice Daily Blood Flow Restriction Training
The Academic Department of Military Rehabilitation (ADMR) is currently conducting a pan-defence, randomised control trial (RCT) investigating the utility of twice daily blood flow restriction training in UK military personnel…
- Trial name
- NCT06334224
- Testing
- Low load resistance training with blood flow restriction, Low load resistance training
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Defence Medical Rehabilitation Centre, UK
Inflammatory Response, Metabolic Disturbance
Cranberry Ingestion and Cycling Related Immunity and Inflammation
This is a randomized, crossover clinical trial with 25 male and female cyclists. Study participants will ingest polyphenol-rich cranberry juice or placebo juice for 4 weeks under double-blinded procedures, and then crossover to…
- Conditions
- Inflammatory Response, Metabolic Disturbance, Immune Suppression
- Trial name
- NCT05407701
- Testing
- Cranberry Juice
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Musculoskeletal Inflammation, Exercise-Induced Muscle Damage
A Clinical Trial to Evaluate the Effects of Peptide Gummies on Markers of Inflammation, Physical Performance, and Recovery
This study will evaluate the effects of Parlay Recover peptide gummies (containing Body Protection Compound BPC-157) on markers of inflammation, physical performance, and recovery in physically active adults.
- Conditions
- Musculoskeletal Inflammation, Exercise-Induced Muscle Damage, Post-Exercise Recovery, Musculoskeletal Pain
- Trial name
- NCT07752381
- Testing
- Parlay Recover Peptide Gummies
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Parlay Wellness