Clinical trials: Exhaled Breath Condensate
Asthma
Metabolomic Analysis of Exhaled Breath Condensate in Asthmatics
Asthma is a chronic inflammatory airway disease. Significant heterogeneity exists in the clinical manifestations and treatment responses in these patients.
- Trial name
- NCT01439737
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Cough, Gastroesophageal Reflux
Exhaled Breath Condensate pH in Patients With Cough Caused by Gastroesophageal Reflux
Cough is the most common complaint for which patients seek medical attention in the United States, accounting for approximately 1 billion dollars in health care expenses annually.
- Trial name
- NCT00451841
- Testing
- RTube Exhaled Breath Condensate Collection System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Massachusetts, Worcester
Obstructive Sleep Apnea
Markers in Exhaled Breath Condensate in Obstructive Sleep Apnoea (OSA) Patients
Patients with obstructive sleep apnoea (OSA) have repetitive episodes of partial or complete upper airway obstruction during sleep.
- Trial name
- NCT00287638
- Testing
- CPAP
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Lung Cancer
Evaluating the Pulmonary Nodule With Imaging and Biomarkers
The study aims to determine if there are defining EBUS and confocal endoscopy features as well as exhaled alveolar gas VOC that can discriminate malignant pulmonary nodules or masses from benign etiology, thereby obviating…
- Trial name
- NCT01739881
- Testing
- Olympus Ultrathin Bronchofibervideoscope (XP260F)
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- National University Hospital, Singapore
Lung Cancer
Serum and Exhaled Breath Condensate MALDI-MS of Lung Cancer. (SPORE)
RATIONALE: Collecting and storing samples of blood and exhaled breath from patients with cancer and from healthy participants to study in the laboratory may help doctors learn more about changes that occur in DNA and identify…
- Trial name
- NCT00898209
- Testing
- protein expression analysis, proteomic profiling, biologic sample preservation procedure
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Exhaled Breath Condensate
"Exhaled Breath Condensate" in Allogeneic Stem Cell Recipients and the Value in Follow-up
The most effective treatment of hematologic malignancies and some benign hematological diseases is allogeneic stem cell transplantation therapy. Pulmonary complications can occur after allogeneic stem cell transplantation.
- Trial name
- NCT02318316
- Testing
- Exhaled breath condensate
- Volunteers
- 80 people
- Sponsor
- Gazi University
Inflammation
Study of the Influence of Various Tidal Volumes on Exhaled Breath Condensate (EBC) in Mechanically Ventilated Patients
The aim of the present study is to evaluate the effect of low (6 ml/kg) and high (12 ml/kg) tidal volume ventilation on inflammatory and oxidative stress biomarkers in the exhaled breath condensate (EBC) of ICU patients without…
- Trial name
- TDEBC (NCT00910026)
- Testing
- low tidal volume ventilation, high tidal volume ventilation
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- Larissa University Hospital
Asthma
Biomarkers of Irritant-Induced and Allergic Asthma
Asthma is a heterogeneous disease, and although much is understood about mechanisms of inflammation in allergic asthma, less is known about mechanisms of irritant-induced asthma (IA).
- Trial name
- NCT02740543
- Testing
- Fluticasone propionate HFA 220
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Acute Respiratory Failure, Critical Illness
Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients
Mechanically ventilated intensive care patients will be sampled for a small amount of exhaled breath condensate from the ventilator circuit and for venous blood.
- Trial name
- NCT06189924
- Testing
- Proteomic analysis of exhaled breath condensate
- Where
- 2 sites in Czechia
- Volunteers
- 200 people
- Sponsor
- The Institute of Molecular and Translational Medicine, Czech Republic
Carboxyhemoglobin, Vital Signs
Evaluation of the Acute Effect of Water-Pipe Smoking on the Respiratory System
Title: The acute effect of water pipe smoking on exhaled nitric oxide (eNO) and exhaled breath condensate (EBC) pulmonary function tests in healthy volunteers Objectives: To evaluate the acute effect of one cession of water pipe…
- Conditions
- Carboxyhemoglobin, Vital Signs, Fractional Exhaled NO, Exhaled Breath Condensate
- Trial name
- NCT01157832
- Where
- 2 sites in Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Asthma
Mometasone and Markers of Airway Inflammation
A post-marketing study to look at the effects of Asmanex on markers of airway inflammation.
- Trial name
- NCT00711165
- Testing
- Mometasone Furoate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Creighton University
Obstructive Sleep Apnea, Inflammation
A Community Study of the Risk for Obstructive Sleep Apnea and Respiratory Inflammation in an Adult Chinese Population
We aimed to investigate the relationship between obstructive sleep apnea (OSA) risk and respiratory inflammation evaluated by the exhaled breath condensate （EBC）interleukin-6 IL-6 and plasma SP-D, based on the Berlin…
- Conditions
- Obstructive Sleep Apnea, Inflammation, Exhaled Breath Condensate, Surveys and Questionnaires
- Trial name
- NCT04832711
- Where
- China
- Volunteers
- 1,270 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
E-cigarettes
Acute Response to Cigarette and E-cigarette Smoking Assesed in Exhaled Breath Condensate in Healthy Smokers of Traditional and E-cigarettes
Electronical cigarettes, also known as "e-cigarettes" are a new phenomenon, which steadily wins more aprobation among smokers. However, there exists no much data concerning the effects of acute exposure to electronic cigarettes…
- Trial name
- NCT03153228
- Where
- Poland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Lung Cancer
Diagnosis of Lung Cancer From Exhaled Breath With Silicon Biophotonic Device
The overall objective of this proposal is to develop a non-invasive, inexpensive and accurate device that detects VOCs in exhaled breath for lung cancer screening.
- Trial name
- NCT01660087
- Testing
- Biophotonic platform for VOC detection
- Where
- 2 sites in Singapore
- Volunteers
- healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Chronic Obstructive Pulmonary Disease (COPD)
Effects of Sulfur Thermal Water Inhalation on Airway Oxidative Stress in COPD Patients
The chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease of the airways characterized by fixed airflow obstruction, with important systemic co-morbidities.
- Trial name
- NCT01664767
- Testing
- Sulfur Thermal water
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Università degli Studi di Ferrara
Severe Asthma
BIOmarkers in Severe AsthMa Patients on Omalizumab Treatment
Eosinophil infiltration and degranulation in airways has been implicated in the pathology of asthma. Periostin is considered to be a marker of eosinophilic inflammation and is one of the highly expressed genes in epithelial cells…
- Trial name
- BIOSAMOT (NCT03361111)
- Where
- Poland
- Volunteers
- 16 people
- Sponsor
- Medical University of Warsaw
Pneumonia, Ventilator-associated
Early Detection of Ventilator-associated Pneumonia (VAP)
The study goal consists in the sequential collection of exhaled breath condensates (EBC) from patients receiving invasive ventilation.
- Trial name
- cheqVAP (NCT02753608)
- Testing
- Collection of exhaled breath condensate
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Jena University Hospital
Bronchiectasis
Exhaled Breath Condensate Assessment in Stable Non-Cystic Fibrotic Bronchiectasis
The measurement of markers in the expired breath condensate has proven to be a useful method for assessing and monitoring airway inflammation.
- Trial name
- NCT03643263
- Where
- China
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
COPD Exacerbation
A Cross Sectional, Diagnostic Accuracy Study to Validate the Use of a New Device(Inflammacheck™) in Diagnosing COPD
A cross-sectional, diagnostic accuracy study to evaluate the use of the 'Inflammacheck™' device in the diagnosis of COPD. Participants will be asked to provide an exhaled breath sample for measurement of their EBC H2O2 using…
- Trial name
- EXHALE 1V (NCT04024657)
- Where
- United Kingdom
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Invasive Pulmonary Aspergillosis
Evaluation of Exhaled Breath Condensate in the Diagnosis of Invasive Pulmonary Aspergillosis
The purpose of this study is to evaluate the diagnostic potential of biomarkers for invasive pulmonary aspergillosis in exhaled breath condensate.
- Trial name
- NCT01247142
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven