Clinical trials: Exosomal RNA
Prostate Cancer
Micro RNAs to Predict Response to Androgen Deprivation Therapy
Identify exosomal micro RNA that predict responses to ADT
- Trial name
- NCT02366494
- Testing
- Bicalutamide, Leuprolide, Goserelin
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Medical College of Wisconsin
Breast Cancer, HER2 Positive Breast Cancer
Exosomal and Free Extracellular RNAs and Proteins as Predictive Biomarkers for HER2 Therapies in Breast Cancer
Primary Objective: (i) To identify panels of RNAs and proteins predictive of response to HER2 targeted agents, considering clinical responses. (ii) To investigate associations between presence vs.
- Conditions
- Breast Cancer, HER2 Positive Breast Cancer, HER2 Negative Breast Cancer
- Trial name
- NCT01840306
- Testing
- Biomarker Analysis
- Where
- 11 sites in Ireland
- Volunteers
- 330 people
- Sponsor
- Cancer Trials Ireland
Gastric Cancer, Gastric Adenocarcinoma
Stomach Cancer Exosome-based Detection
Gastric cancer continues to have a poor prognosis primarily due to the inability to detect it in its early stages. This study will develop and validate a blood assay to facilitate the non-invasive detection of gastric cancer.
- Conditions
- Gastric Cancer, Gastric Adenocarcinoma, Gastric Cancer Stage, Gastric Neoplasm
- Trial name
- DESTINEX (NCT06342427)
- Testing
- DESTINEX
- Where
- 3 sites in United States, Japan
- Volunteers
- 809 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Prostate Cancer (Diagnosis), Bone Metastasis
Plasma Exosomal RNA Signature for Prostate Cancer Bone Metastasis
Brief Summary: This prospective, multicenter study aims to discover, develop, and validate a plasma exosomal RNA-based signature as a rule-out test for predicting bone metastasis in prostate cancer, using baseline treatment-naïve…
- Conditions
- Prostate Cancer (Diagnosis), Bone Metastasis, PSMA PET, Liquid Biopsy
- Trial name
- EXO-MET (NCT07553754)
- Where
- 9 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Xijing Hospital
Pancreas Adenocarcinoma
Circulating Extracellular Exosomal Small RNA as Potential Biomarker for Human Pancreatic Cancer
This study is for the verification of biomarkers for pancreatic cancer treatment using small RNA liquid biopsy, combined with EUS-FNA tissues.
- Trial name
- NCT04636788
- Testing
- Venous sampling
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Lung Cancer (Diagnosis)
Serum Exosomal Long Noncoding RNAs as Potential Biomarkers for Lung Cancer Diagnosis
The study is to investigate the sensitivity and specificity of serum exosome noncoding RNA as a biomarker for the diagnosis of lung cancer
- Trial name
- NCT03830619
- Testing
- collect samples
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology