Clinical trials: Exosome
Healthy Subjects, Exosome
A Study to Investigate HLA-G Targeted Exosome (SOB100) in Healthy Subjects
The investigational drug, SOB100, is an HLA-G targeted exosome equipped with a nanobody namely anti-HLA-G VHH on the exosome membrane.
- Conditions
- Healthy Subjects, Exosome, Targeted Therapy
- Trial name
- αHLA-G Exo-01 (NCT07219940)
- Testing
- SOB100
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Shine-On Biomedical Co., Ltd.
Laser Therapy, Exosomes
Enhancing Skin Rejuvenation Using Laser and Exosomes
Enhancing Skin Rejuvenation A Single-Blind, Randomized Control Study on the Combined Efficacy of Aerolase 1064 nm YAG Laser and Exosomes Derived from Umbilical Cord Mesenchymal Stem Cells
- Trial name
- NCT07281690
- Testing
- 1064-nm Nd:YAG Laser Treatment, Topical Umbilical Cord-Derived Exosomes (UC-MSC Exosomes)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Laser Beamer Skincare
Exosomes, Newborn
Exosome microRNAs as Potential Biomarkers of Metabolic Bone Disease of Prematurity
Metabolic bone disease of prematurity (MBDP) is caused by insufficient content of calcium, phosphorus, and organic protein matrix in preterm infants or bone metabolism disorder, which is one of the complications affecting the…
- Conditions
- Exosomes, Newborn, Bone Diseases, Metabolic
- Trial name
- NCT06368154
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hunan Children's Hospital
Exosome, Skin Regeneration
Clinical Observation of Exosomes in Patients After Q-switched Laser Surgery
the goal of this half-face controlled study is to evaluate the effect of exosome-containing liquid dressings on the recovery of patients after Nd:YAG laser 532 treatment.
- Conditions
- Exosome, Skin Regeneration, Laser
- Trial name
- NCT06279039
- Testing
- Exosome liquid dressing
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Exosomes, Connective Tissue
Exercise-induced Changes in Exosomes
The proposed study aims to shed light on the function/importance/relevance of exercise-induced changes in exosomes to connective tissues. Exosomes are known to increase robustly in response to exercise.
- Conditions
- Exosomes, Connective Tissue, Exercise
- Trial name
- NCT05616234
- Testing
- Resistance Exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Lung Neoplasm, Squamous Cell Carcinoma
Serum Exosomal miRNA Predicting the Therapeutic Efficiency in Lung Squamous Carcinoma
This is an observational prospective bi-center study of 50 patients operated on advanced squamous cell carcinoma. The main aim is to investigate the efficacy of serum exosomal miRNA as a biomarker for predicting the therapeutic…
- Conditions
- Lung Neoplasm, Squamous Cell Carcinoma, Exosomes
- Trial name
- NCT05854030
- Testing
- collect plasma samples and clinical features
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Intracerebral Hemorrhage；Circulating Exosomes
Application of Circulating Exosomes in Early Diagnosis and Prognosis Evaluation After Intracerebral Hemorrhage
The purpose of this study is to observe the relationship between the changes of circulating exosomes and the development and outcome of the disease in patients with intracerebral hemorrhage, and to search for early serum markers…
- Trial name
- NCT05035134
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Postoperative Delirium, General Anesthesia
The Disorder of Circadian Clock Gene and Early Cognitive Dysfunction After General Anesthesia
Postoperative cognitive dysfunction (POCD) is a common postoperative complication in patients aged 65 and over, which refers to cognitive function changes such as memory decline and attention deficit after anesthesia and surgery.
- Conditions
- Postoperative Delirium, General Anesthesia, Exosomes, Clock Gene
- Trial name
- NCT04421872
- Testing
- receiving general anesthesia
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital