Clinical trials: Experimental
Chronic Obstructive Pulmonary Disease (COPD), Cachexia
Therapeutic Efficacy of Nutritional Supplementation in Cachexia Associated With Chronic Pulmonary Disease
Pulmonary cachexia, observed in individuals with chronic obstructive pulmonary disease (COPD) is a multifactorial syndrome characterized by disruptions in energy metabolism, increased protein degradation, and an impaired capacity…
- Trial name
- CATCH-PulMo (NCT07288619)
- Testing
- N-3 Polyunsaturated Fatty Acids (PUFA), Vitamin D
- Where
- Pakistan
- Volunteers
- 45 people
- Sponsor
- Safeer Khan
Medication Adherence, Quality of Life
ECHO-COPD: Impact of a Pharmacist-Led Health Belief Model-Based Educational Intervention Among Chronic Obstructive Pulmonary Disease Patients
Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease associated with substantial morbidity and mortality, impaired quality of life, and healthcare costs.
- Conditions
- Medication Adherence, Quality of Life, Cost, Health Belief Model
- Trial name
- ECHO-COPD (NCT07815353)
- Testing
- Pharmacist-Led HBM-Based Educational Intervention
- Where
- Saudi Arabia
- Volunteers
- 140 people
- Sponsor
- Rabia Hussain
Anxiety Disorders
Examining Behavioral Strategies for Enhancing Therapists' Delivery of Exposure Therapy
The goal of this study is to test a targeted training for overcoming known barriers to the uptake and quality delivery of exposure therapy among community mental health providers.
- Trial name
- STRIVE (NCT04035057)
- Testing
- Behaviorally Enhanced Training, Standard Didactic Training
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bradley Hospital
Reflexology, Epilepsy
Reflexology on Seizure Frequency, Fatigue, Stress and Sleep Quality in Epilepsy Patients
Epilepsy is among the diseases that cause loss of neurological abilities regardless of any trauma. Reflexology is one of the complementary therapies based on activating the body's self-healing power through special hand…
- Conditions
- Reflexology, Epilepsy, Fatigue, Stress
- Trial name
- NCT06120101
- Testing
- Reflexology Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ataturk University
Healthy Participants
An Investigational Study to Evaluate the Effects of Experimental Medication BMS-986256 in Healthy Participants
The purpose of this study is to evaluate the effects of the experimental medication BMS-986256 in healthy participants.
- Trial name
- NCT03634995
- Testing
- BMS-986256
- Where
- 2 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Problematic Smartphone Use, Digital Distraction
Reducing Digital Distractions to Improve Time Management Among Nursing Students
This study examines whether a short digital abstinence intervention can reduce digital distractions and improve time management among undergraduate nursing students.
- Conditions
- Problematic Smartphone Use, Digital Distraction, Time Management
- Trial name
- NCT07467057
- Testing
- Digital Abstinence Intervention
- Where
- Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- Cairo University
Postoperative Pain
Prediction of Acute Postoperative Pain and Analgesic Consumption
Pain is an expected part of surgical recovery but effective pain management remains challenging. The high variability in postoperative pain experience and analgesic treatment response between patients is part of the challenge.
- Trial name
- MIRPEX-3 (NCT02230865)
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Kasper Grosen
Paranoia, Psychotic Disorders
Racial Disparities in the Expression of Paranoia
Paranoia is a pattern of thinking in which people feel suspicious or believe others may want to harm them. It can occur in many people, not only those with a mental health diagnosis, and it can affect daily life, relationships…
- Trial name
- NCT07460453
- Testing
- Guided Visual Imagery Task
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Indiana University
HIV Infections
Anti-HIV Activity and Safety of 3 Different Doses of Mifepristone in HIV Infected People
The purpose of this study is to determine the anti-HIV activity and safety of 3 different doses of mifepristone (also known as VGX-410 and RU486) in HIV infected people.
- Trial name
- NCT00099645
- Testing
- Mifepristone
- Where
- 10 sites in United States
- Volunteers
- 48 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Moral Injury, Perceived Stress
Role Model-Based Ethics Education and Moral Injury Prevention in Second-Year Medical Students
This study examines whether role model-based ethics education can reduce moral injury and perceived stress, and improve resilience, among second-year medical students in Taiwan.
- Conditions
- Moral Injury, Perceived Stress, Resilience, Ethics Education
- Trial name
- NCT07656402
- Testing
- Role Model-Based Ethics Education (Standard Intensity), Role Model-Based Ethics Education (Enhanced Intensity)
- Where
- Taiwan
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Chun Lun Hsu
Psychological Resilience, Career Decision Making
Effect of a Nurse-Led Transition Program on Resilience and Career Decisions in Senior Students
The transition to higher education is a critical stage that affects young people's academic, emotional, and professional development.
- Trial name
- NCT07823881
- Testing
- Nurse-Led On-Campus Experiential Transition Program
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Amyotrophic Lateral Sclerosis (ALS)
Personalized Antisense Oligonucleotide Therapy for a Participant With TARDBP ALS
This research project entails delivery of a personalized antisense oligonucleotide (ASO) drug designed for a single participant with amyotrophic lateral sclerosis (ALS) due to a pathogenic variant in TARDBP.
- Trial name
- NCT07703462
- Testing
- nL-TARDB-002
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- n-Lorem Foundation
Advanced Solid Cancers
An Investigational Immunotherapy Study of BMS-986301 Alone or in Combination With Nivolumab, and Ipilimumab in Participants With Advanced Solid Cancers
The main purpose of this study is to characterize the safety, tolerability, dose limiting toxicities, best route of administration, maximum tolerated dose, maximum administered dose, or alternative dose of BMS-986301 alone or in…
- Trial name
- NCT03956680
- Testing
- BMS-986301, Nivolumab, Ipilimumab
- Where
- 5 sites in United States, Canada
- Volunteers
- 54 people
- Sponsor
- Bristol-Myers Squibb
Muscular Dystrophy (DMD)
Study of an Investigational Drug, RO7239361 (BMS-986089), in Ambulatory Boys With DMD
The purpose of this study is to determine the safety and tolerability of RO7239361 in boys with Duchenne Muscular Dystrophy with any genetic mutation.
- Trial name
- NCT02515669
- Testing
- RO7239361
- Where
- 12 sites in United States, Canada
- Volunteers
- 43 people
- Sponsor
- Hoffmann-La Roche
Experimental, Control Condition
Using Ecological Momentary Data to Inform a Web Intervention for Romantic Partners Concerned About Their Loved Ones' Drinking
Aim 1. Couples (N=50 dyads) with a Concerned Partner (CP) and a Drinking Partner (DP) will independently complete baseline and follow-up surveys and a 21-day EMA with three daily reports on their communication and DP's drinking.
- Trial name
- NCT06670794
- Testing
- Web-based intervention for concerned partners, Psychoeducation control
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Florida
Human Immunodeficiency Virus (HIV)
Phase II Safety and Acceptability of an Investigational Injectable Product, TMC278LA, for Pre-Exposure Prophylaxis
This is a multi-site, double-blinded, two-arm, two:one, randomized, trial comparing the safety of an intramuscular (IM) injection of TMC278 LA to a placebo given once every eight weeks over a 40 week period among sexually active…
- Trial name
- TMC278LA (NCT02165202)
- Testing
- Rilpivirine
- Where
- 4 sites in United States, South Africa and 1 more
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- PATH
Cannabis, Abuse Liability
Repeated CBD Administration and Cannabis Outcomes
This outpatient study examines how cannabidiol (CBD) affects the behavioral and pain-relieving effects of cannabis.
- Conditions
- Cannabis, Abuse Liability, Experimental Pain in Healthy Human Participants
- Trial name
- NCT07434895
- Testing
- Cannabidiol, Medium Dose, Cannabidiol, Higher Dose, Active Inhaled Cannabis
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Hannah Harris
Schizophrenia
A Clinical Study to Investigate the Effect of an Investigational Drug as an Added Medication to an Antipsychotic, in Adults With Schizophrenia, as Measured Positron Emission Tomography (PET) Imaging
A clinical study to investigate the effect of an investigational drug as an added medication to an antipsychotic, in adults with schizophrenia, as measured positron emission tomography (PET) imaging .
- Trial name
- NCT04038957
- Testing
- SEP-363856
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Autism Spectrum Disorder, Infant Development
Experimental Techniques for Early Identification of Autism
This project deals with essential challenges in the context of Autism Spectrum Disorder, benefiting from a longitudinal design in infancy and a cutting-edge electroencephalogram/eye-tracking integrated approach.
- Trial name
- NCT05712512
- Testing
- Neurodevelopmental assessment, Electrophysiological and eyetracking recordings
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Eugenio Medea
Chronic Stroke
CompARing Long terM Outcomes in Chronic Stroke Survivors Across Investigational Assessments Following a Prescribed Upper Extremity Exercise Program
The purpose of the study is to compare assessments of arm function following a standard exercise program in chronic stroke patients.
- Trial name
- NCT05659875
- Testing
- Standard Occupational Therapy Arm Exercise Program
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- The University of Texas Health Science Center, Houston