Clinical trials: Exposure, Environmental, open to volunteers
Skin Cancer, Heat Tolerance
Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals
The escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans.
- Conditions
- Skin Cancer, Heat Tolerance, Heat-related Illness, Hyperthermia
- Trial name
- ICARUS (NCT07510061)
- Testing
- Controlled Heat and Ultraviolet Radiation Exposure Protocol
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Risk Factors, Polypharmacy
Telecommunication Technology-based Online Survey
The aim of this study is to identify and assess new health-associated risk factors, including clinical-pharmacological risk factors. The cohort is built using telecommunication approaches.
- Conditions
- Risk Factors, Polypharmacy, Drug Interactions, Self Medication
- Trial name
- NCT06159699
- Testing
- Online Survey, Genetic Testing
- Where
- Russia
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Stress (Psychology), Environment
Stress Through Audition: Uptake, Recovery, Oscillations During Nature Exposure
The protocol the investigators propose aims to address certain gaps by developing a multimodal paradigm, based on: Induction of acute stress via the Maastricht Acute Stress Test (MAST), a standardised protocol recognised for its…
- Trial name
- SAURON (NCT07857239)
- Testing
- Natural soundscape auditory exposure, Urban soundscape auditory exposure
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Prostate Cancer, Leukemia
Natural History Study of Early Life Exposures in Agriculture (ELEA)
Study Description: ELEA is an observational cohort study that will collect exposure information and biospecimens from the adult children of the Agricultural Health Study (AHS) cohort (https://aghealth.nih.gov/about; Protocol…
- Conditions
- Prostate Cancer, Leukemia, Breast Cancer, Melanoma
- Trial name
- NCT07328516
- Where
- United States
- Volunteers
- 64,277 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Pulmonary Function
Service and Health Among Deployed Veterans
The purpose of the study is to better understand the health, including lung health, of Veterans who deployed in support of Operation Enduring Freedom (OEF), Operation Iraqi Freedom (OIF), or Operation New Dawn (OND) and other…
- Trial name
- SHADE (NCT02825654)
- Where
- 6 sites in United States
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PFAS, Environmental Exposures
Use of Bile Acid Binding Resins to Decrease PFAS Levels Via Colesevalem in Veterans Study
The goal of this study is to test the efficacy and feasibility of Colesevelam administration (50% of the recommended dose) to reduce serum PFAS concentration in the Veteran population who have serum PFAS levels that exceed the…
- Conditions
- PFAS, Environmental Exposures, Occupational Exposure to Chemicals, Military Exposure
- Trial name
- PAVERS (NCT07592858)
- Testing
- Colesevelam
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Environmental Exposure
Assessing and Addressing Community Exposures to Environmental Contaminants
The purpose of this study is to build on our equitable, eight-year Tribal-academic partnership with the Ramapough Nation of northern NJ to advance tradition-centered farming practices and management strategies supporting…
- Trial name
- NCT06315140
- Testing
- Nutrition
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Environmental Exposure, Asthma
Effects of Environmental Fungal Exposure on Bronchial Asthma, ABPA and Bronchiectasis
This study is a prospective, observational study of patients aged 18-80 years with clinical diagnosis of bronchial asthma, allergic bronchopulmonary aspergillosis (ABPA), bronchiectasis and healthy subjects.
- Conditions
- Environmental Exposure, Asthma, Bronchiectasis, ABPA
- Trial name
- NCT07313904
- Where
- China
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Ningbo University
Air Pollution Exposure, Oxidative Stress
Savannah Environmental Nutrition Study (SENS): Nutrition Intervention to Reduce Air Pollution-Related Airway Inflammation and Oxidative Stress
This pilot clinical trial will evaluate the feasibility and potential health effects of a nutrition-based intervention among adults living in communities affected by air pollution near the Port of Savannah, Georgia.
- Conditions
- Air Pollution Exposure, Oxidative Stress, Airway Inflammation
- Trial name
- NCT07797413
- Testing
- Antioxidant- and Nutrient-Rich Food-Based Nutrition Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Georgia Southern University
Environmental Exposure
Behavioural Intervention to Decrease Exposure to Emerging Chemical Pollutants
The purpose of this study is to evaluate the effectiveness of a behavioural intervention designed to reduce exposure to environmental chemical pollutants among adults in Spain.
- Trial name
- INPOL (NCT07465315)
- Testing
- Guidelines from the public healthcare system, INPOL healthy lifestyle informative guidelines
- Where
- 5 sites in Spain
- Volunteers
- 740 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Allergic Contact Dermatitis, Metal Allergy
Environmental Exposure to Heavy Metals, Nanoparticles, and Emergent Contaminants and Risk of Allergic Diseases
The goal of this clinical trial is to collect environmental, bio-humoral, and clinical data derived from patients with allergic contact dermatitis (ACD) and systemic metal allergic syndromes related to the exposure to heavy…
- Conditions
- Allergic Contact Dermatitis, Metal Allergy, Food Allergy, Nickel Sensitivity
- Trial name
- MATRIOSKA (NCT06529913)
- Testing
- Collection of environmental, biological, and clinical data
- Where
- 2 sites in Italy
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lead Poisoning, Environmental Exposure
A Study to Assess the Efficacy of Public Health Campaigns in Reducing Lead Exposure
This clinical trial aims to evaluate the effectiveness of targeted public health campaigns in reducing lead exposure among adults living in urban communities with known environmental lead hazards.
- Trial name
- NCT07632937
- Testing
- Intensive Public Health Campaign, Standard Information Dissemination
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- International Health Strategies LLC
Somatic Mutation
Linking Somatic Mutation Rate With Baseline Exposure in East Palestine
The goal of this study is to This research team is conducting this study to develop methods to measure the biological impact of exposure to the chemicals released following the February 3, 2023 train derailment on residents of…
- Trial name
- NCT06357845
- Testing
- Survey, Biological specimen collection, Communications about study updates and future research opportunities
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Aging, Mortality
Human Observatory Study
The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at the individual and population level.
- Conditions
- Aging, Mortality, All-cause Mortality, Life Expectancy
- Trial name
- HOS (NCT07646782)
- Testing
- Multi-Domain Ecological and Clinical Data Linkage
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Physical Inactivity, Environmental Exposure
Reconstructing Schoolyards With Greenery to Increase Schoolchildren's Physical Activity and Mitigate Climate Changes
By reconstructing schoolyards with greenery, physical activity levels among children can be increased at the population level and also mitigate health and environmental risks resulting from rising climate changes in urban areas.
- Conditions
- Physical Inactivity, Environmental Exposure, Mental Health Wellness 1
- Trial name
- NCT05865782
- Testing
- Schoolyard reconstruction
- Where
- Sweden
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Genetic Predisposition, Exposure, Environmental
Mayo Clinic Precure - Prospective Study
The goal of this observational study is to 1) better understand and predict biological processes before disease begins or is identified, 2) study genomic and environmental contributors to disease, 3) identify ways to stop disease…
- Trial name
- NCT07332598
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Environmental Exposure, Health Behavior
The Barts Charity Children's Environmental Health Clinic
The study will be based from a newly formed NHS service, the children's environmental health service. Participants will be children with a known chronic respiratory condition.
- Conditions
- Environmental Exposure, Health Behavior, Asthma in Children, Environmental Illness
- Trial name
- BCCEHC (NCT06447974)
- Testing
- Exposure mitigations
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Cardiopulmonary Function, Environmental Exposures
Effects of LPG and Ventilation Interventions on Reducing HAP and Improving Cardiopulmonary Health
The goal of this clinical trial is to evaluate the independent and synergistic effects of liquefied petroleum gas (LPG) substitution and improved ventilation on household air pollution (HAP) reduction and cardiopulmonary health.
- Trial name
- NCT07005193
- Testing
- Cooking ventilation facilities, Using liquefied gas for cooking, Using solid fuels for cooking
- Where
- 3 sites in China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Plasma Glucose Following Prolonged Heat Exposure
Glycemic Control Following Occupational Work in a Hot Environment
Occupational workers regularly perform physically demanding tasks in hot environments, exposing them to heat stress and potential dehydration.
- Trial name
- NCT06982612
- Testing
- Hot environment, Temperate condition
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Inflammation, Normal Controls
Natural History of the Human Biological Response to Environmental Exposure and Injury
Background: Environmental exposures like pollution, diet, and stress can help cause human diseases, or make them worse. Researchers want to better understand how injury and inflammation are caused by these exposures.
- Conditions
- Inflammation, Normal Controls, Metabolic Disease
- Trial name
- NCT04888923
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)