Clinical trials: Exposure, Environmental
Asthma Childhood, Asthma
Advancing Diagnosis and Treatment of Pediatric Asthma
Asthma is one of the most common chronic diseases in children, and treatment success often depends on proper inhaler use and consistent medication adherence.
- Conditions
- Asthma Childhood, Asthma, Inhalation Spacers
- Trial name
- Care4Asthma (NCT07500246)
- Testing
- Whizz spacer system, AeroChamber Plus® Flow-Vu®
- Where
- Luxembourg
- Volunteers
- 208 people
- Sponsor
- Luxembourg Institute of Health
Health Knowledge, Environmental Exposure
Planetary Health and Environmental Justice in Construction Career Education
This study tests whether a new educational curriculum can help high school students in construction career programs better understand how building design affects community health and environmental justice.
- Conditions
- Health Knowledge, Environmental Exposure, Attitude, Practice
- Trial name
- EJT-CTE (NCT07315919)
- Testing
- Community-Centered Design Curriculum with EJT, Traditional Technical Curriculum
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stanford University
Metabolic Diseases, Neurological and Mental Health Conditions
Growing Up in Singapore Towards Healthy Outcomes
This study aims to examine the role of genetic and epigenetic factors, maternal nutrition, lifestyle, emotional health, and other environmental factors in pregnancy or postpartum period that can influence future maternal risk of…
- Conditions
- Metabolic Diseases, Neurological and Mental Health Conditions, Genetic Predisposition, Skin Condition
- Trial name
- GUSTO (NCT01174875)
- Where
- Singapore
- Volunteers
- 1,247 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Healthy
Measuring Environmental Tobacco and Cannabis: Pollutants and Exposures
This is an unblinded pilot study of an environmental exposure to secondhand cannabis smoke in one group of healthy nonsmokers.
- Trial name
- CAN03 (NCT06030674)
- Testing
- Secondhand cannabis emissions/smoke exposure
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Rumination
Effect of Environment on the Central and Peripheral Nervous System
The main goal of this study is to understand how different environments influence both mental responses, like overthinking (rumination), and physical reactions, such as heart rate and blood pressure, after a challenging task.
- Trial name
- RUMI (NCT06778356)
- Testing
- Built environment, Natural environment
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Seasonal Allergic Rhinitis
Evaluating the Efficacy of Ragweed-SPIRE Following Exposure to Ragweed Allergen in an Environmental Exposure Chamber
The purpose of this study is to determine whether Ragweed-SPIRE is safe and effective at reducing allergy symptoms in people who suffer from allergy to Ragweed pollen
- Trial name
- NCT02061709
- Testing
- Ragweed-SPIRE
- Where
- 5 sites in Canada
- Volunteers
- 280 people
- Sponsor
- Circassia Limited
Diabetic Nephropathies, Diabetes Mellitus, Type II
Environmental Exposure to Lead and Progressive Renal Insufficiency in Type II Diabetic Nephropathy
Background The relationship between long-term heavy lead exposure and chronic interstitial nephropathy is well recognized in the previous literatures.
- Trial name
- NCT00237952
- Testing
- EDTA chelating agents
- Where
- 2 sites in China
- Sponsor
- Chang Gung Memorial Hospital
Congenital Malformation
Pregnancy Environment and Newborn Malformations
Congenital malformations rate is about 3% in France. There are already 5 registries in France, covering about 16% of French births: Paris Registry, (about 38 000 births /year), Alsace Registry, (about 23 000 births/year)…
- Trial name
- PENEW (NCT01613638)
- Testing
- meconium samples + maternal self-questionnaire
- Where
- 11 sites in France
- Volunteers
- 1,657 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Vapors; Inhalation, Cancer
Addressing Tetrachloroethylene Exposure in an Impacted Community
Groundwater in Martinsville, IN, is contaminated by volatile organic compounds (VOCs), tetrachloroethylene (PCE) and trichloroethylene (TCE).
- Conditions
- Vapors; Inhalation, Cancer, Volatile Organic Compounds
- Trial name
- NCT05819996
- Testing
- Environmental educational campaign
- Where
- United States
- Volunteers
- 510 people
- Sponsor
- Purdue University
Asthma
NHALES (Natural History of Asthma With Longitudinal Environmental Sampling)
Background: Asthma is a serious clinical and public health problem. Researchers want to collect data to better understand how bacteria and other things in the environment can affect people's asthma.
- Trial name
- NCT02327897
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Healthy
Occupational Exposure of Firefighters to Environmental Pollutants
The aim of the current trial is to assess the exposure of firefighters (FF) to environmental pollutants emitted from fires, to explore the association of exposure with their health status and to compare these data with those of…
- Trial name
- NCT05256212
- Testing
- exposure to environmental contaminants
- Where
- Israel
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Tooth Extraction Site Healing, Alveolar Ridge Preservation
Biomaterials Exposed to Oral Environment: Which One is the Appropriate Option?
After tooth extraction, bone loss can compromise future dental implant treatment. Dentists often use biomaterials to preserve bone, but in many cases these materials are left exposed to the oral environment, where saliva and…
- Trial name
- NCT07589751
- Testing
- Alveolar Ridge Reconstruction
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Environmental Exposure
Interventions to Decrease Heat Stress Among Latinx Farmworkers in Idaho
The goal of this study is to collaborate with farmworker, community organizations, and labor contractors/employers to develop workplace- and individual-level interventions, and evaluate the efficacy of those interventions in…
- Trial name
- NCT05807282
- Testing
- Interventions to Decrease Heat Stress among Latinx Farmworkers in Idaho
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boise State University
Asthma Acute, Respiratory
Children's Health, Respiratory Inflammation and Short-term Air Pollution
The goal of this study is to see if physical activity in high air pollution is worse than rest in high air pollution.
- Trial name
- CHERISH (NCT07431021)
- Testing
- science lesson, PE Lesson
- Where
- United Kingdom
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Environmental Exposure, Temperature Change, Body
The Effect of IEQ on Cognition and Health
The goal of this study is to learn about the effect of heat and humidity on cognition and health. The main question[s] it aims to answer are: type of study: interventional participant population: 20-40years, both gender, healthy…
- Conditions
- Environmental Exposure, Temperature Change, Body, Condition, Healthy
- Trial name
- IEQ-HUM (NCT05972187)
- Testing
- Temperature and Humidity
- Where
- Netherlands
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Cat Allergy
Effectiveness of Cat-PAD to Treat Cat Allergy in Cat Allergic Subjects
Cat allergy is an increasingly prevalent condition, affecting 10-15% of patients with allergic rhinoconjunctivitis and/or asthma.
- Trial name
- NCT00729508
- Testing
- Cat-PAD
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Circassia Limited
Pulmonary Function
Service and Health Among Deployed Veterans
The purpose of the study is to better understand the health, including lung health, of Veterans who deployed in support of Operation Enduring Freedom (OEF), Operation Iraqi Freedom (OIF), or Operation New Dawn (OND) and other…
- Trial name
- SHADE (NCT02825654)
- Where
- 6 sites in United States
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
SDH-Related Familial Paraganglioma, SDHx-Related Syndromes
Impact of Environmental Exposures on Tumor Risk in SDHx-mutation Carriers
The primary objective of the PGL.EXPO-2 study is to test the hypothesis that exposure (occupational, environmental and/or domestic) to succinate dehydrogenase inhibitors (SDHi) could contribute to tumor emergence in subjects…
- Conditions
- SDH-Related Familial Paraganglioma, SDHx-Related Syndromes, SDH Gene Mutation, Environmental Exposure
- Trial name
- PGLEXPO2 (NCT06408402)
- Where
- 20 sites in France
- Volunteers
- 1,300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lead Poisoning, Environmental Exposure
A Study to Assess the Efficacy of Public Health Campaigns in Reducing Lead Exposure
This clinical trial aims to evaluate the effectiveness of targeted public health campaigns in reducing lead exposure among adults living in urban communities with known environmental lead hazards.
- Trial name
- NCT07632937
- Testing
- Intensive Public Health Campaign, Standard Information Dissemination
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- International Health Strategies LLC
Allergic Conjunctivitis
The INVIGORATE 2 Trial: A Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis
The INVIGORATE 2 Trial: A single-center, randomized, double-masked, crossover design, vehicle-controlled, Phase 3 clinical trial to assess the efficacy and safety of reproxalap ophthalmic solution (0.25%) compared to vehicle in…
- Trial name
- NCT05234554
- Testing
- Reproxalap Ophthalmic Solution (0.25%), Vehicle Ophthalmic Solution
- Where
- Canada
- Volunteers
- 131 people
- Sponsor
- Aldeyra Therapeutics, Inc.