Clinical trials: Exposure, Environmental
Food Selection, Environmental Exposure
Dismantling the U.S. Social Norm of the "Kids' Food" Archetype (REACH Project)
This project is the first stage of a health promotion campaign to shift social norms about marketing and feeding children ultra-processed foods.
- Trial name
- NCT06266533
- Testing
- Conventional Ultra-processed Food Nutrition Education, Arts-based Ultra-processed Food Nutrition Education
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Xerostomia
Dry Mouth Toothpaste Study - Comparing Two Toothpastes With Arginine
This is a clinical investigation to measure the changes in the oral environment resulting from a 3 month exposure to an arginine containing toothpaste. This study is a double blind, randomized controlled, parallel design.
- Trial name
- NCT06365047
- Testing
- 8% Arginine toothpaste, 1000 ppm F toothpaste
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Tufts University
Endocrine Disrupting Chemicals, Environmental Exposure
Personalized Mobile Intervention to Reduce Exposure to Endocrine Disrupting Chemicals in Adults of Child-Bearing Age
The goal of this intervention study is to determine to what extent the Million Marker (MM) program reduces users' endocrine disruption chemical (EDC) exposure levels and changes their environmental health awareness and behaviors.
- Conditions
- Endocrine Disrupting Chemicals, Environmental Exposure, Health Literacy, Bisphenol A
- Trial name
- NCT05780047
- Testing
- Mail-in Urine Test for EDCs
- Where
- United States
- Volunteers
- 434 people, healthy volunteers welcome
- Sponsor
- Million Marker Wellness, Inc.
Obesity
Environmental Health Effects on Your Physiology
This study evaluates the associations between exposure to air pollutants, green space, and the gut microbiome and metabolome.
- Trial name
- HYPHY (NCT03986814)
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Colorado, Boulder
Retinoblastoma
Research on the Environment and Children's Health: Retinoblastoma
The purpose of the research study is to learn more about the causes of retinoblastoma and to identify possible risk factors in the parents of patients with retinoblastoma.
- Trial name
- NCT00582049
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Seasonal Allergic Rhinitis, Healthy Subjects
A Pilot Monocenter Study to Assess Cellular and Soluble Biomarkers in Nasal Secretions
Allergic Rhinitis is an inflammatory disease which causes an influx of inflammatory cells and cytokines into the nasal mucosa. These biomarkers can also be found in the nasal secretions.
- Trial name
- NCT00297843
- Testing
- allergen challenge (grass pollen), nasal lavage
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Noise Exposure
The Effect of a Reduced Noise Environment on the Response Time of the Anesthesia Provider
This project will investigate whether reduction in ambient light and elimination of noise during induction and emergence from anesthesia influences the response time of the anesthesia provider to auditory and visual alarms when…
- Trial name
- NCT03507855
- Testing
- Reduced noise, Normal
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Joshua Uffman
SDH-Related Familial Paraganglioma, SDHx-Related Syndromes
Impact of Environmental Exposures on Tumor Risk in SDHx-mutation Carriers
The primary objective of the PGL.EXPO-2 study is to test the hypothesis that exposure (occupational, environmental and/or domestic) to succinate dehydrogenase inhibitors (SDHi) could contribute to tumor emergence in subjects…
- Conditions
- SDH-Related Familial Paraganglioma, SDHx-Related Syndromes, SDH Gene Mutation, Environmental Exposure
- Trial name
- PGLEXPO2 (NCT06408402)
- Where
- 20 sites in France
- Volunteers
- 1,300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dentin Sensitivity
Use of Biomaterials as Desensitizer Agents
Aim: to investigate the clinical effectiveness over 12 weeks of three different biomaterials, nano-hydroxyapatite based, in the therapy of the dental sensitivity.
- Trial name
- NCT02770573
- Testing
- Cavex Bite&White ExSense, Kuraray Teethmate™ Desensitizer, Ghimas Dentin Desensitizer
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Università degli Studi di Sassari
Specific Phobia, Specific Phobia, Situational
Using Immersive Virtual Reality to Treat Pediatric Anxiety
Anxiety is a common and impairing problem for children. The principle treatment for pediatric anxiety involves facing a child's fears in a stepwise approach through a therapeutic exercise called exposures.
- Conditions
- Specific Phobia, Specific Phobia, Situational, Specific Phobia, Animal, Specific Phobia, Natural Environment
- Trial name
- NCT04504773
- Testing
- Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Johns Hopkins University
Disorders of Environmental Origin
Reducing Pesticide Exposure in Minority Families
This is a community-based participatory research program focusing on pesticide contamination in migrant farmworker families.
- Trial name
- NCT00014807
- Testing
- Reducing Pesticide Exposure in Minority Families
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Exposure to Environmental Pollution, Adverse Effect of Unspecified General Anesthetic
Anesthetic Gas Leakage in Children During Tonsillectomy: a Comparison of Cuffed and Uncuffed Tracheal Tubes
Fires and operating room pollution may occur when anesthesia gases leak into the oropharynx during airway surgery. Investigators sought to measure the concentrations of anesthetic gases that leak into the mouth of children…
- Trial name
- NCT02725164
- Testing
- oxygen concentration, nitrous oxide concentration, carbon dioxide concentration
- Volunteers
- 31 people
- Sponsor
- State University of New York at Buffalo
Occupational Health, Sick Leave
Effects of Regulatory Tools on Work Environment and Employee Health
This study evaluates the effects of the Labour Inspection Authority's regulatory tools on workplace exposures to prevent employee ill health.
- Conditions
- Occupational Health, Sick Leave, Occupational Exposure
- Trial name
- NCT03855163
- Testing
- Inspection visits, Guidance workshops, Online risk assessment tool
- Where
- 130 sites in Norway
- Volunteers
- 2,555 people, healthy volunteers welcome
- Sponsor
- National Institute of Occupational Health, Norway
Environmental Tobacco Smoke Exposure, Depression
Healthy Outcomes of Pregnancy Education
The purpose of this study is to determine if an integrated intervention addressing active smoking, environmental tobacco smoke exposure, depression and intimate partner violence, would improve pregnancy outcome among African…
- Conditions
- Environmental Tobacco Smoke Exposure, Depression, Partner Abuse, Tobacco Smoking
- Trial name
- NCT00381823
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 1,750 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Environmental Exposure
Assessing and Addressing Community Exposures to Environmental Contaminants
The purpose of this study is to build on our equitable, eight-year Tribal-academic partnership with the Ramapough Nation of northern NJ to advance tradition-centered farming practices and management strategies supporting…
- Trial name
- NCT06315140
- Testing
- Nutrition
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Genetic Predisposition, Exposure, Environmental
Mayo Clinic Tapestry 2.0: Applying Multi-Omics for Scientific Discovery
The purpose of this study is to use multi-omics testing on samples collected from Mayo Clinic patients to build and expand on what has been learned about genomic data.
- Trial name
- NCT06456320
- Where
- 3 sites in United States
- Volunteers
- 10,000 people
- Sponsor
- Mayo Clinic
Grass Allergy, Rhinoconjunctivitis
ToleroMune Grass Follow on Study
Grass pollen allergens are recognised as a major cause of allergic diseases in humans and animals. Worldwide, at least 40% of allergic patients are sensitised to grass pollen allergens and between 50-90% of hayfever or seasonal…
- Trial name
- NCT01923779
- Volunteers
- 163 people
- Sponsor
- Circassia Limited
Asthma, Allergy
Efficacy of Air Cleaners in Asthmatics Allergic to Cat in ALYATEC Environmental Exposure Chamber
The aim of this study is to determine the efficacy of Rowenta® "Intense Pure Air XL" air cleaner on the early and late bronchial response, in cat-allergic asthmatic patients during an allergen exposure in ALYATEC environmental…
- Trial name
- NCT03928561
- Testing
- Active intense Pure Air XL air cleaner
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Alyatec
Allergic Conjunctivitis
The INVIGORATE Trial: A Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis.
The INVIGORATE Trial: A Randomized, Double-masked, Crossover Design, Phase 3 Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis.
- Trial name
- NCT04207736
- Testing
- Reproxalap Ophthalmic Solution (0.25%), Vehicle Ophthalmic Solution
- Where
- Canada
- Volunteers
- 95 people
- Sponsor
- Aldeyra Therapeutics, Inc.
Congenital Heart Disease
Study on the Relationship Between Maternal Exposure to Environmental Factors and Fetal Congenital Heart Disease
The objective of this study is to research the relationship between maternal exposure to environmental factors and fetal congenital heart disease in a community-based case-control study.
- Trial name
- NCT02914392
- Where
- 2 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine