Clinical trials: Exposure
Healthy
Examination of the Link Between Sun Exposure Routine and Bacteria Population of the Skin
These days many studies are conducted testing the symbiosis between the bacteria population to the human body's functioning. The research of the connection between the skin condition and the bacteria population is in its early…
- Trial name
- NCT02763163
- Testing
- Sun exposure routine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Institute for Skin Research, Israel
Pregnancy, Sickness Absence
Active Pregnancy Policy at Work. Greater Wellbeing and Lower Sickness Absence
In a cluster randomized design it will be investigated whether teaching local leaders how to implement active pregnancy policy results in less sickness absence among their pregnant employees.
- Conditions
- Pregnancy, Sickness Absence, Occupational Exposure
- Trial name
- AGp (NCT03002987)
- Testing
- Active Pregnancy policy
- Where
- Denmark
- Volunteers
- 866 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Traumatic Brain Injury
Impact of Pre-Military Life Experiences/Exposures on Active-Duty Service Members' Psychological Health
The goal of this observational study is to learn about the impact of historic and current Traumatic Brain Injuries on a Marine Battalion.
- Trial name
- NCT06070025
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Sweetness Liking Adaptation
Liking Adaptation to Beverages of Varying Sweetness Levels Following Prolonged Exposure
This is a double-blind, controlled, parallel, randomized sensory study. The study will consist of two cohorts; habitual regular full-calorie Carbonated Soft Drink (CSD) consumers and habitual low-calorie CSD consumers.
- Trial name
- NCT05010408
- Testing
- Flavored carbonated soft drink (CSD) at different sweetness levels
- Where
- Mexico
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Chronic Pain
Green Light Exposure in Healthy Volunteers Exposure in Normal Human Volunteers
This research project is intended to understand the mechanisms of action for the pain-relieving properties of visual green light exposure.
- Trial name
- NCT05295225
- Testing
- Green Light Emitting Diode, White Light Emitting Diode
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Pulmonary Inflammation, Cytotoxicity
Pulmonary and Systemic Effects of Exposure to Wood Smoke
This is study is to assess pulmonary and systemic effects of exposure to wood smoke. Healthy volunteers will be expose under two different occasion to wood smoke and filtered air under two separated occasions with an interval of…
- Trial name
- NCT03302117
- Testing
- Wood smoke exposure
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Umeå University
Atherosclerosis, Type 2 Diabetes (T2D)
Arsenic, Disordered Glucose Homeostasis and Atherosclerosis
Investigators will recruit 250 subjects; Group A will consist of 100 prediabetic patients with an A1c of 5.7%-6.4%. Group B will consist of 100 patients with uncontrolled T2D defined as either a) an A1c of 6.5%-7.9% without…
- Trial name
- EMERALD-D (NCT02759289)
- Where
- United States
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Endocrine Diseases
Male:Female Birth Ratios and Phthalate Levels
Objective 1: To assess environmental exposure to chemicals/toxins, including phthalates, among rural and urban Mexican American men and women (n=300), aged 18 to 40, in urban Baytown, TX and rural Rio Grande Valley (Hidalgo…
- Trial name
- NCT00903318
- Testing
- Questionnaire
- Where
- 3 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
HIV Infection
Demonstrating Safety and Effective Delivery of Daily Oral Pre-exposure Prophylaxis (PrEP) for Sex Workers in India
Female sex workers (FSWs) in India are at high risk of HIV infection, and while correct and consistent condom use is an effective means of preventing HIV transmission, many FSWs have difficulty insisting on their use.
- Trial name
- PrEP-India (NCT02148094)
- Testing
- Truvada
- Where
- 2 sites in India
- Volunteers
- 1,325 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Antiretroviral Treatment Outcomes
Trial to Assess the Impact of PrEP to Tenofovir Gel on the Efficacy of Tenofovir-containing ART on Viral Suppression
The HIV/AIDS pandemic remains among the investigators greatest public health challenges. In the absence of an effective vaccine, focus has shifted to other prevention strategies such as pre-exposure prophylaxis.
- Trial name
- TOAST (NCT01387022)
- Testing
- Tenofovir, lamivudine and efavirenz
- Where
- South Africa
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Centre for the AIDS Programme of Research in South Africa
Substance Use Disorders, HIV Infections
Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People
This is a multi-phased study, funded through a National Institute on Drug Abuse (NIDA) K24 grant that aims to ultimately refine a virtual reality tool through qualitative and quantitative research targeting HIV and substance…
- Trial name
- NCT05816083
- Testing
- Virtual Reality Tool
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Biomarkers of Air Pollution Exposure
Biomarkers of Exposure to Air Pollutants (AEROTOX-2)
Nowadays, an increase of inflammatory chronic diseases and/or tumors incidence has been reported in part due to the rising in life expectancy.
- Trial name
- AEROTOX-2 (NCT02765529)
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Carious Exposure of Pulp
Evaluation of MTA Versus Biodentine as Pulpotomy Agents in Immature First Permanent Molars
Aim of the study: To compare the clinical and radiographic outcomes of mineral trioxide aggregate (MTA) and Biodentine as vital pulp therapy materials (pulpotomy) of cariously exposed vital immature mandibular first permanent…
- Trial name
- NCT03838094
- Testing
- Biodentine, MTA
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gihan M Abuelniel ,PhD
Radiation Exposure
Comparison Of Effective Radiation Shielding Between Rampart IC, M1128 Shield vs Conventional Apron And Shields In Clinical Interventional Procedures
Previous studies have documented that orthopedic injuries and musculoskeletal pain are a likely result of wearing heavy leaded aprons.
- Trial name
- RAMPART (NCT05347290)
- Testing
- Rampart IC, M1128, Lead Apron and Ancillary Shield, Rampart IC, M1128 and Lead Apron
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Tuberculosis
Study to Evaluate the Safety and Immunogenicity of VPM1002 in Comparison With BCG in HIV-exposed/-Unexposed Newborn Infants in South Africa
Goal of Serum Institute of India Limited (SIIL) is the development of a recombinant urease C-deficient listeriolysin expressing BCG vaccine strain (VPM1002) as a safe, well tolerated and efficacious vaccine against tuberculosis…
- Trial name
- NCT02391415
- Testing
- VPM1002, BCG, VPM1002(Hyg+)
- Where
- 4 sites in South Africa
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Serum Institute of India Pvt. Ltd.
PrEP Uptake
MI-based PrEP Intervention
Gay, bisexual and other men who have sex with men (MSM) are the group at highest risk of HIV infection in the United States. Pre-exposure prophylaxis (PrEP) has demonstrated high efficacy in preventing HIV infection among MSM.
- Trial name
- NCT03313765
- Testing
- Motivational interviewing (MI), Standard-of-care
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Social Anxiety Disorder
Very Brief Exposure: Development of a Novel Exposure Modality for Social Anxiety Disorder in Transition-Age Youth
The goal of this clinical trial is to identify the circuit activations by very brief exposure (VBE) among youth with social anxiety disorder (SAD) in order to develop a novel intervention for those with SAD.
- Trial name
- NCT06526260
- Testing
- Very Brief Exposure to Facial Expressions
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Exposure to Secondhand Smoke in Neonatal Infants
Motivational Incentives to Reduce Secondhand Smoke in NICU Infants' Homes
A randomized, controlled, parallel group design will be used to test whether a Secondhand Smoke Exposure program initiated in the hospital and completed in the home using motivational interviewing plus motivational incentives…
- Trial name
- NCT01726062
- Testing
- Motivational Interviewing plus Incentives, Conventional Care (CC)
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Metabolism
Effect of Genetics on Metabolism of Efavirenz
This study will evaluate the effects of genetics on metabolism of the anti-HIV medicine efavirenz (Sustiva) and will see if Efavirenz interacts with bupropion (Zyban or Wellbutrin), a drug commonly used to treat depression and to…
- Trial name
- NCT00245986
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Drug Interaction
Assessment of Drug-drug Interactions Between Masculinizing Hormone Therapy and Antiretroviral Agents Concomitantly for Pre-exposure Prophylaxis Among Transgender Men
There are currently no published studies addressing drug-drug interactions (DDI) between masculinizing hormone therapy (MHT) and pre-exposure prophylaxis (PrEP) among transgender men (TGM).
- Trial name
- NCT04593680
- Testing
- Emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg (F/TDF) and emtricitabine 200 mg/tenofovir alafenamide 25 mg (F/TAF)
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
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