Clinical trials: Exposure Occupational
Exposure to Chemical Pollution, Occupational
Exposure to Chemical Substances Within Household Waste Incineration Plants
Employees of household waste incineration plants (UIOM) are exposed to multiple chemical substances that can pose a risk to their health.
- Trial name
- Chem-Expo (NCT06183866)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Asbestos Exposure
Investigation of the Anti-Cancer Activity of Artichoke Extract in an Asbestos-Exposed Population
This is a single-arm phase II trial to assess the biological activity (in a sub-cohort using a Simon two-stage Phase II design) and toxicity of Artichoke Whole Phytocomplex Concentrate (WPC).
- Trial name
- ABOCA1 (NCT02076672)
- Testing
- Artichoke WPC
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Occupational Exposure
Chronic Adaptations to Spinal Flexion Exposure
An experimental study, which will aim to compare changes of trunk mechanical properties and neuromuscular control following spinal flexion exposure in crane operators and control subjects.
- Trial name
- NCT05752006
- Testing
- Repeated trunk flexion
- Where
- Slovenia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Sharps Injuries, Needlestick Injuries
AI-Supported Gamified Training for Sharps Injury Prevention in Nurses
This study aims to evaluate the effect of a Health Belief Model (HBM)-based, artificial intelligence (AI)-supported gamified training program on nurses' knowledge and attitudes toward the prevention of sharps injuries.
- Conditions
- Sharps Injuries, Needlestick Injuries, Occupational Exposure
- Trial name
- NCT07562867
- Testing
- Experimental: Intervention Group, control group
- Volunteers
- 36 people
- Sponsor
- Baskent University
Skin Cancer, Occupational Exposure
Virtual Sun Safe Workplaces Ph II (SSW Works)
Americans who work outdoors are exposed to an extreme amount of solar ultraviolet radiation over a lifetime that substantially increases their risk for developing skin cancer.
- Trial name
- NCT05774600
- Testing
- SSW Works, Minimal Information Control
- Where
- United States
- Volunteers
- 543 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Healthy
Occupational Exposure of Firefighters to Environmental Pollutants
The aim of the current trial is to assess the exposure of firefighters (FF) to environmental pollutants emitted from fires, to explore the association of exposure with their health status and to compare these data with those of…
- Trial name
- NCT05256212
- Testing
- exposure to environmental contaminants
- Where
- Israel
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
COPD, Exposure Occupational
Characterization of Professional COPD Related to Exposure to Organic Dust - Mean Follow up at 6 Years
The main objective of the BALISTIC research program is to characterize COPD related to organic particles (of which the model is agricultural COPD) in comparison with tobacco-related COPD, at the clinical, functional (at rest and…
- Trial name
- BALISTIC 2 (NCT03468101)
- Testing
- Pulmonary Function Testing
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Sars-CoV2
Longitudinal Study of Covid-19 Infection Among HCW in a French University Hospital
The aim of the study is to determine the incidence o of SARS-cov2 infection among health care workers highly exposed to covid 19 during 10 weeks et to analyze the determinants of their occupational and environmental exposure.
- Trial name
- PRECOVIA (NCT04362267)
- Testing
- self-administered questionnaire, SARS-Cov2 testing
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Influenza, Influenza Vaccines
Safety and Tolerability Study of GlaxoSmithKline (GSK)1557484A Vaccine in Adults at Occupational Risk for Influenza A (H5N1) Exposure
The purpose of this study is to evaluate the safety and tolerability of GSK Biologicals' vaccine GSK1557484A against pandemic avian (H5N1) influenza in adults at occupational risk of exposure to the virus.
- Trial name
- NCT01788228
- Testing
- Influenza A (H5N1) Virus Monovalent Vaccine, Adjuvanted (A/Indonesia)
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Influenza
Inactivated Influenza A/H5N1 Vaccine in Adult Subjects at Risk of Occupational Exposure to Live H5N1 Viruses
This is a single center, open-label, Phase I/II study in up to 100 adult subjects, aged 18 years and older who are at occupational risk of exposure to live H5N1 viruses.
- Trial name
- NCT00417560
- Testing
- inactivated influenza A/H5N1 vaccine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Psychological Stress, Anxiety
NeuroFinance Human Stress Trial During Financial and Informational Volatility
The NeuroFinance Human Stress Trial (NFHST-2026-001) is a decentralized observational clinical study designed to evaluate how financial market volatility, economic uncertainty, digital media exposure, and information-driven…
- Conditions
- Psychological Stress, Anxiety, Emotional Stress, Autonomic Nervous System Dysfunction
- Trial name
- NFHST (NCT07622589)
- Testing
- Wearable Physiologic Monitoring Platform
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Brain and Central Nervous System Tumors
Developing Interview Questions to Estimate Workplace Exposure to Electric and Magnetic Fields
RATIONALE: Electric and magnetic fields may increase the risk of cancer. Developing interview questions that accurately estimate a person's exposure to electric and magnetic fields may help doctors learn about the long-term…
- Trial name
- NCT00340054
- Testing
- questionnaire administration, study of high risk factors
- Where
- 2 sites in United States
- Volunteers
- 108 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Exposure to Ionizing Radiation, Occupational Exposure to Radiation
Use of Large Field of View During Image Acquisition for Coronary Angiography
Coronary angiography exposes patients and physicians to ionizing radiation. The purpose of this study is to evaluate the routine use of large field of view during image acquisition for coronary angiography.
- Conditions
- Exposure to Ionizing Radiation, Occupational Exposure to Radiation, Radiation Injury
- Trial name
- XRay Reduction (NCT01334931)
- Testing
- Large field of view arm, Medium field of view
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Antimicrobial Resistance (AMR), ESBL
One Health Determinants of Rectal Colonization by ESBL-Producing Enterobacterales in the Community
This multicenter cross-sectional observational study aims to determine the prevalence of rectal colonization by extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales among community-dwelling adults in Argentina and…
- Conditions
- Antimicrobial Resistance (AMR), ESBL, Gut Microbiota Dysbiosis, Environmental Exposure
- Trial name
- NCT07818109
- Where
- Argentina
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Interstitial Lung Diseases (ILD), Pulmonary Emphysema
Clinical Utility of LIBS Multi-Element Imaging and the IFF Algorithm in Chronic Lung Diseases
PNEUMO-LIBS is a multicenter, non-interventional observational study designed to evaluate whether multi-element tissue imaging by Laser-Induced Breakdown Spectroscopy (LIBS), combined with an artificial intelligence-based…
- Conditions
- Interstitial Lung Diseases (ILD), Pulmonary Emphysema, Chronic Lung Diseases, Occupational Lung Diseases
- Trial name
- PNEUMO-LIBS (NCT07597187)
- Where
- 3 sites in France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Grenoble
Chronic Obstructive Pulmonary Disease (COPD), Environmental Exposure
Detection and Characterization of COPD in Dairy Farmers
A pilot study from the investigators group suggests that the prevalence of chronic obstructive pulmonary disease (COPD) among dairy farmers is higher than in the general population.
- Trial name
- BALISTIC (NCT02540408)
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
HIV Infections
HIV Non Occupational Post-Exposure Prophylaxis (PEP)
This study will evaluate how safe and tolerable a combination of taking three-drugs will be for the purpose of preventing HIV transmission after a high-risk sexual contact exposure in HIV uninfected adults.
- Trial name
- NCT00594646
- Testing
- TRUVADA + Raltegravir
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fenway Community Health
Occupational Diseases
Hazardous Substances Injuries
This clinical study aims to evaluate the effectiveness and safety of [intervention or treatment] in patients with [clinical condition].
- Trial name
- Substances (NCT07879261)
- Testing
- Retrospective Administrative Data Assessment
- Where
- Israel
- Volunteers
- 1,951 people
- Sponsor
- Sergio Gabriel Susmallian
History of Exposure to Silica or Asbestosis, Positive Testing for ANA as a Marker of Systemic Autoimmune Diseases
Effects of Silica and Asbestos Fibres on the Efferocytosis Capacities of Macrophages
Evaluation of the efferocytosis capacities of blood Monocyte Derived Macrophages (MDM) from patients with a history of asbestosis or silica exposure and comparison of these capacities with those of MDM from healthy donors.
- Trial name
- MacFibOsis (NCT04473742)
- Testing
- Blood collection, Blood sample
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Rennes University Hospital
Hearing Loss, Noise-Induced, Eustachian Tube Dysfunction
Hearing/ET/Vestibular in Balloon Pilots
This study looks at whether working as a hot-air balloon pilot-being exposed to burner noise, changes in air pressure/temperature, and vertical acceleration-is linked to changes in hearing, Eustachian tube function, and…
- Conditions
- Hearing Loss, Noise-Induced, Eustachian Tube Dysfunction, Vestibular Disorders, Occupational Exposure
- Trial name
- FLIGHT-EAR (NCT07200310)
- Testing
- Non-invasive audiologic and vestibular assessments
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital