Clinical trials: External Ventricular Drainage Associated Infection
Wound Contamination
Prospective Randomised Study for Use of CHG Dressing at Entry Site of EVD's to Reduce EVD-associated Infections
The objective of this study is to assess the efficacy of 3M™ Tegaderm™ CHG I.V. Securement Dressing at the entry-site of a EVD in reducing quantity of microorganisms (CFU/cm2) after a time period of 5 days as a surrogate marker…
- Trial name
- EVDAI (NCT02078830)
- Testing
- 3M™ Tegaderm™ CHG I.V. Securement Dressing
- Where
- Switzerland
- Volunteers
- 57 people
- Sponsor
- University Hospital, Basel, Switzerland
Intrathecal Infection, External Ventricular Drainage Associated Infection
Cerebrospinal Fluid IL-6, IL-8 and PCT as Early Marker of an Intrathecal Infection in Neurosurgical Patients
The value of CSF IL-6, IL-8 and Procalcitonin in detecting an early diagnosis of intrathecal infection in neurosurgical patients with an external ventricular drainage is evaluated.
- Trial name
- NCT02875808
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Medicine Greifswald
Acute Brain Injury, Hydrocephalus
VentricuLostomy AssoCiaTed InfeCtions (LACTIC): Focus on CSF Lactate and Sampling Site
This observational study involving patients with acute brain injury undergoing treatment with an external ventricular drain consists of three subprojects, aiming to: 1.
- Conditions
- Acute Brain Injury, Hydrocephalus, External Ventricular Drain, External Ventricular Drainage Associated Infection
- Trial name
- LACTIC (NCT07380477)
- Testing
- Sampling of blood and cerebrospinal fluid
- Where
- Denmark
- Volunteers
- 148 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Health Care Associated Infection
Care Bundle to Limit External Ventricular Drain Associated iNfections
The aim of our study is to reduce the incidence of External ventricular drain (EVD)-related infections by implementing a bundle of measures including updated care protocoles and training of residents, nurses and nurses…
- Trial name
- CLEAN-EVD (NCT07619625)
- Testing
- Bundle of measures including updated care protocoles and training of residents, nurses and nurses assistants
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Ventricular Drain Related Infection, Nosocomial Infection
Novel Diagnostic Methods to Identify External Ventricular Drain Associated Infections
External ventricular drain infections are difficult to identify with current diagnostic methods. Initiation of antibiotic treatment is usually supported by indirect methods of bacterial infection, such as clinical signs or…
- Conditions
- Ventricular Drain Related Infection, Nosocomial Infection, Infection, Bacterial, Ventriculitis, Infectious
- Trial name
- EVD Infect II (NCT05904535)
- Testing
- Cerbrospinal fluid sampling.
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska University Hospital