Clinical trials: Extraction, Tooth
Dental Caries, Primary Teeth
Carie Care, Chemomechanical Caries Removal Technique in Primary Teeth
Chemomechanical caries removal systems have emerged as a possible valuable alternative to conventional rotary caries removal techniques in pediatric patients.
- Trial name
- NCT05538559
- Testing
- Chemomechanical caries removal by Carie-Care, Mechanical caries removal by Atraumatic Restorative Technique
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Hams Hamed Abdelrahman
Impacted Third Molar Tooth, Temporomandibular Disorder
Assessing a New Jaw Support Device During Third Molar Extractions
During mandibular 3rd molar (wisdom tooth) extractions, when a downward force is placed on the patient's jaw, the patient must tense his/her jaw muscles to oppose it.
- Trial name
- NCT03975920
- Testing
- The Restful Jaw Device
- Where
- 4 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tooth, Impacted
Comparison Between the Lingually Based and the Buccally Based Triangular Flap Design in the Surgical Removal of Impacted Mandibular Third Molars
The primary objective of this study was to compare between the lingually based triangular flap with the buccally based triangular flap in the surgical removal of impacted mandibular third molars.
- Trial name
- NCT04192864
- Testing
- Lingually based triangular flap, Buccally based triangular flap
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Nourhan M.Aly
Deep Caries
Selective Removal Technique With or Without a Bioactive Material for Deep Caries Lesions
Objectives: To evaluate and compare clinical and radiographic success of the selective removal to soft dentine technique in one step using calcium silicate cement (Biodentine) vs.
- Trial name
- NCT04743219
- Testing
- Selective removal to soft dentin, Biodentine, Selective removal to soft dentin, No Base
- Where
- Spain
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Osteoradionecrosis of the Jaw
Platelet-Rich Fibrin for Preventing Osteoradionecrosis After Dental Extractions
The goal of this clinical trial is to learn whether platelet-rich fibrin (PRF) can help prevent osteoradionecrosis (ORN) after dental extractions in adults who previously received radiation therapy to the head and neck.
- Trial name
- NCT07856875
- Testing
- Platelet-rich fibrin (PRF), Standard Dental Extraction Care
- Where
- 2 sites in Canada
- Volunteers
- 112 people
- Sponsor
- University of Manitoba
Tooth Extraction, Tooth Extraction Site Healing
Comparison of Intraligamentary Anesthesia With the Inferior Alveolar Nerve Block for the Extraction of Mandibular Molars.
Local anaesthesia or numbing is done before tooth extraction. This study compares two different methods of numbing molar teeth before extraction.
- Trial name
- NCT06611865
- Testing
- Intraligamentary anaesthesia, Inferior alveolar nerve block
- Where
- Pakistan
- Volunteers
- 535 people
- Sponsor
- Hamza Zia Ahmed
Badly Decayed Anterior Maxillary Teeth
Immediate Implant Placement With Immediate Provisionalization Into Extraction Sockets With Labial Plate Dehiscence Defects Within the Maxillary Esthetic Zone
Immediate tooth replacement with implants into extraction sockets has become a common clinical procedure regarding implant survival, osseointegration and esthetics.
- Trial name
- NCT03676244
- Testing
- immediate implant in defected anterior maxillary esthetic zone
- Volunteers
- 15 people
- Sponsor
- Cairo University
Tooth Loss and Rehabillitation, Immediate Implant Placement in Mandibular Molar Extraction Sockets
Comparison Between Xenograft and Extended PRF as Jumping Gap Grafting Material Versus Natural Healing of the Socket Without Any Material.
This study aims to clinically and digitally evaluate immediate implants placed in mandibular molar extraction sockets and compare the outcomes of xenograft, e-PRF, and no grafting material within the jumping gap.
- Conditions
- Tooth Loss and Rehabillitation, Immediate Implant Placement in Mandibular Molar Extraction Sockets, Jumping Gap
- Trial name
- NCT07797452
- Testing
- Xenograft jumping gap filling material, e-PRF jumping gap filling material
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Alveolar Ridge Preservation, Dental Implants
Leukocyte and Platelet-rich Fibrin (L-PRF) Effects on Alveolar Ridge Preservation. A Randomized Controlled Clinical Trial.
The goal of this clínical trial is to compare in patients needing extraction of anterior teeth the effects of leukocyte-and platelet-rich fibrin (L-PRF) for alveolar ridge preservation versus spontaneous healing.
- Trial name
- NCT05662709
- Testing
- Tooth extraction, Alveolar ridge preservation with L-PRF
- Where
- Spain
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Orthodontic Extraction, Orthodontic Treatment
A Comparative Assessment of Post Extraction Pain in Orthodontic Patients to Evaluate the Effects of Early Engagement of Tooth with Orthodontic Wires. a Single Center Randomized Clinical Trial (RCT)
The goal of this clinical trial is to determine if the timing of tooth extractions (before or after initial orthodontic treatment) affects pain levels in patients who need bilateral extractions of first premolars in the upper…
- Conditions
- Orthodontic Extraction, Orthodontic Treatment, Orthodontic Treatment Via Premolar Extraction
- Trial name
- NCT06582836
- Testing
- The objective of the study was to investigate the effect of prior engagement of tooth with orthodontic appliance on post extraction pain among orthodontic patients
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Missing Teeth
Bone-Implant Contact Surface Influence on Dental Implant Stability
This study aims to evaluate the changes in the stability and bone-implant contact surface of implants of the same macro-design placed with particle grafting in the fresh extraction socket, without grafting, and placed in healed…
- Trial name
- NCT06178796
- Testing
- Dental implant
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Wound Healing, Magnesium Level
Relationship Between Magnesium Depletion Score and Extraction Socket Healing
The surgical extraction of an impacted tooth is one of the most common procedures in oral surgery. Following extraction, the tissue undergoes repair and regeneration through a process known as socket healing (SH).
- Conditions
- Wound Healing, Magnesium Level, Wisdom Tooth Removal
- Trial name
- NCT06891846
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Alveolar Socket Preservation
Clinical, Histological and Micro-computed Tomographic Evaluation of Neoformed Tissue in Post-extraction Sockets Covered With Platelet-rich Fibrin (PRF) Membrane: a Randomized Controlled Trial
The platelet-rich fibrin (PRF), belongs to a new generation of plasma concentrate with biomechanical processing simplified and without the need for handling blood biochemistry.
- Trial name
- NCT02300246
- Testing
- Platelet-Rich Fibrin
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Marcos de Oliveira Barceleiro
Dental Anxiety, Preoperative Anxiety
Passiflora Incarnata for Dental Extraction Anxiety
This study looks at whether Passiflora incarnata (passionflower extract) can help reduce anxiety before tooth extraction. Male participants who feel high anxiety before the procedure will receive either passionflower extract or…
- Trial name
- NCT07790029
- Testing
- Passiflora incarnata extract
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ömer faruk Kaygısız
Tooth Extraction, Immediate Implant Placement
Immediate Implant Placement Using Volume-Stable Collagen Matrix Combined With rhPDGF-BB
The goal of this study is to test a volume-stable collagen matrix in combination with recombinant human platelet-derived growth factor-BB, specifically in patients who have an immediate implant placement for teeth #5-#12.
- Trial name
- NCT06038695
- Testing
- Xenogeneic Volume-Stable Collagen (VCMX) graft with growth factor-BB
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- I-Ching Wang
Class II Malocclusion
Effect of Bilateral Distalization of Upper First Molars in a Group of Patients After Extraction of Maxillary Second Molars
There is a scarcity in the current literature regarding such appliance and its effect on distalizing the first maxillary molar in absence of the second molar.
- Trial name
- NCT05592977
- Testing
- Intra-Oral Distalizing Device
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Alveolar Ridge Resorption After Extraction
Alveolar Ridge Changes Post Tooth Extraction With Socket Shield Without Immediate Implant Placement"
This study aimed to evaluate the dimensional changes in the alveolar ridge after tooth extraction using the socket shield technique without immediate implant placement.
- Trial name
- CBCT (NCT06658860)
- Testing
- Modified Socket Shield Technique, Conventional Tooth Extraction
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Soaad Tolba Mohammed Tolba Badawi
Biofilm Removal, Gingival Abrasion
Capacity of Biofilm Removal and Gingival Abrasion After Utilization Medium and Soft Toothbrushes
This study compared the removal of dental biofilm between soft and medium toothbrushes. The patients refrained from performing mechanical or chemical plaque control for 96 hours to allow dental biofilm accumulation on the tooth…
- Trial name
- NCT01125007
- Testing
- Two kind toothbrushes
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Franciscan University Center
Tooth Impacted
Acute Inflammation After Wisdom Tooth Removal
Third molar (wisdom teeth) extraction is one of the most frequent intervention in dentistry. Nevertheless, little is known about the level of general body inflammation of subjects with impacted or semi-impacted third molars.
- Trial name
- OTTO-SYST (NCT03048175)
- Testing
- Wisdom tooth removal
- Volunteers
- 40 people
- Sponsor
- University of Pisa
Osteoradionecrosis of the Jaw, Medicine Related Osteonecrosis of the Jaw
L-PRF in Prevention of ORN and MRONJ Following Tooth Extractions;v3.0
Osteoradionecrosis (ORN) and medication-related osteonecrosis of the jaw (MRONJ) are debilitating complications following dental extractions in patients who have received head and neck radiotherapy or antiresorptive therapy.
- Trial name
- NCT07585123
- Testing
- L-PRF, Standard Extraction
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Swansea Bay University Health Board