Clinical trials: Extraction, Tooth
Periodontal Pocket, Periodontal Bone Loss
Using Xenograft Combined With Barrier Membrane to Improve the Formation of Deep Periodontal Pockets
To evaluate the clinical effect of site preservation after third molars extraction by using tooth extraction of third molars with site preservation using bio-oss and bio-guide in preventing the formation of deep periodontal…
- Conditions
- Periodontal Pocket, Periodontal Bone Loss, Impacted Third Molar Tooth
- Trial name
- NCT06318247
- Testing
- site preservation
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Dental Plaque
Effect of Powered Toothbrushing and Dental Flossing Sequence on Dental Plaque Removal
This randomized crossover clinical trial evaluated whether the sequence of powered toothbrushing and dental flossing affects dental plaque removal.
- Trial name
- NCT07737626
- Testing
- Powered Toothbrushing, Dental Flossing
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Hypercholesterolemia
The Effect Of Simvastatin On Bone Remodeling In Socket Of Mandibular Teeth
Simvastatin has been reported to promote osteoblastic activity and inhibit osteoclastic activity by enhancing the expression of BMP2.
- Trial name
- NCT01085149
- Testing
- Simvastatin
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Impacted Wisdom Teeth
Efficacy Study of IV Ibuprofen vs IV Acetaminophen Post Surgical Extraction
This study will compare how effective a single dose of an intravenous (IV) ibuprofen is when compared to single dose of IV acetaminophen in reducing pain.
- Trial name
- Caldolor (NCT02133326)
- Testing
- Caldolor, Ofirmev
- Where
- 2 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Tufts University School of Dental Medicine
Mouth and Tooth Diseases, Tooth, Impacted
Ketamine on Acute Pain in Females and Males
The purpose of the study is to determine whether equal subanesthetic doses of racemic ketamine is equally effective on females and males after surgical removal of third molars
- Trial name
- NCT00232492
- Testing
- Ketamine 0,1 mg/kg males, Ketamine 0,3 mg/kg males, Ketamine 0,5 mg/kg males
- Where
- Norway
- Volunteers
- 128 people
- Sponsor
- Ullevaal University Hospital
Overcoming the Failure of Anesthesia in the Mandibular Teeth
How Successful is Supplemental Intraseptal Anaesthesia in Patients With Mandibular Teeth Extraction or Irreversible Pulpitis
Introduction: Local anesthetic failure is an unavoidable aspect of dental practice. A number of factors contribute to this, which may be related to either the patient or the operator.
- Trial name
- NCT03880409
- Testing
- 2% lidocaine with 1:000,000 epinephrine, 4% articaine with 1:000,000 epinephrine
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taibah University
Tooth Extraction Status Nos
Efficacy of aPDT in Reducing Pain and Swelling Following Molar Extraction Surgery- Blinded Randomized Controlled Clinical Trial
This project aims to evaluate the effect of antimicrobial photodynamic therapy (aPDT) on the reduction of swelling and postoperative pain in lower molar extraction procedures.
- Trial name
- NCT03818906
- Testing
- Molar extraction - Control Group, aPDT + Molar Extraction - Test Group 1, Infrared + Molar Extraction - Test Group 2
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Immediate Dental Implants, Thin Labial Plate of Bone Pre-extraction
Autogenous Tooth Bone Graft Versus Allogeneic Bone Graft Around Dental Implant in Aesthetic Zone
24 patienta with non restorable anterior teeth underwent extraction with immediate implant installation using bone grafts either autogenous tooth bone graft or allogenic bone graft Autogenous tooth bone graft group (study group)…
- Conditions
- Immediate Dental Implants, Thin Labial Plate of Bone Pre-extraction, Hopeless Tooth in Esthetic Zone
- Trial name
- NCT06773104
- Testing
- immediate implant with allogenic bone graft, Allogeneic bone graft with immediate implant placement
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tanta University
Malocclusion, Long Face Syndrome
Effect of Extraction Vs Non-extraction Orthodontic Treatment on Vertical Facial Dimension
The aim of the current clinical trial was to evaluate the effects of premolar extractions compared with non-extraction orthodontic treatment on the skeletal vertical dimension of the face.
- Conditions
- Malocclusion, Long Face Syndrome, Crowding, Tooth
- Trial name
- NCT04151875
- Testing
- Extraction orthodontic treatment, Non-extraction orthodontic treatment
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Conservative Versus Non-conservative Treatment for Severe Dental Caries
The purpose of this study is to compare the effectiveness of the conservative (pulpectomy) versus non-conservative treatment (tooth extraction) of primary molars affected with severe dental caries associated to oral…
- Trial name
- NCT01858298
- Testing
- Conservative treatment: pulpectomy and composite resin crown, Non-conservative treatment: Tooth extraction
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo
Premature Loss of Primary Molars, Space Maintenance
Space Changes After Premature Loss of Lower First Primary Molars in Children Using Digital Scanning
This prospective split-mouth clinical study aims to evaluate space changes in the mandibular dental arch following premature extraction of the lower first primary molar in children aged 3 to 5.5 years.
- Conditions
- Premature Loss of Primary Molars, Space Maintenance, Dental Arch Development, Pediatric Tooth Extraction
- Trial name
- NCT06965777
- Where
- Egypt
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anesthesia, Local
Evaluation of Buffered Local Anesthesia in Dental Extraction.
To compare pain during injection, onset of anesthesia and effectiveness of anesthesia using buffered versus non- buffered 2% lidocaine with 1:80,000 adrenaline in dental extraction.
- Trial name
- NCT04773236
- Testing
- sodium bicarbonate 8.4%, 2%lidocaine with 1:80.000 epinphrine, Mixing pen (onset buffering system)
- Volunteers
- 100 people
- Sponsor
- University of Baghdad
Quality of Life, Dental Caries
Impact of Minimally Invasive Restorative Techniques on Pregnant Women Oral Health Related Quality of Life
Aim of the study was to compare the effect of chemo-mechanical caries removal methods using Papacarie-Duo and alternative restorative treatment (ART) on the Oral Health Related Quality of Life (OHRQoL) of pregnant women.
- Trial name
- NCT04619264
- Testing
- Papacarie, Atraumatic Restorative Treatment
- Where
- Egypt
- Volunteers
- 162 people
- Sponsor
- Nourhan M.Aly
Dental Caries in Children
Two Different Minimal Invasive Techniques in Caries Removal of Primary Teeth
Pain control during dental treatments is the most challenging situations that face the pediatric dentist especially in young and fearful or anxious child.
- Trial name
- NCT06759311
- Testing
- ART, Brix 3000, Carie Move
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Hams Hamed Abdelrahman
Hypomineralization of Enamel, Dental Fear
Analysis of Treatment Outcomes in Patients Affected by Molar-Incisor Hypomineralization (MIH)
The aim is to long-term evaluate extraction or restoration therapy, of first permanent molars with extensive treatment needs as a result of severe MIH in a national multicenter study concerning dental fear and anxiety, oral…
- Conditions
- Hypomineralization of Enamel, Dental Fear, Quality of Life
- Trial name
- GuREx-MIH (NCT06228989)
- Testing
- Restorative therapy, Extraction therapy
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Malocclusion
Effect of Cyclic Loading (Vibration) on Orthodontic Tooth Movement
To gather data indicating whether or not the OrthoAccel device speeds tooth movement in people who use orthodontics (braces).
- Trial name
- NCT00830947
- Testing
- OrthoAccel Device
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- OrthoAccel Technologies Inc.
Alveolar Ridge Preservation, Tooth Extraction
A 14 Weeks Longitudinal Study to Investigate the Effect of Leukocyte- Platelet Rich Fibrin Plug on the Quality of the Newly Formed Bone in Ridge Preservation Procedure Following a Tooth Extraction. It is a Clinical, Radiographic and Histomorphometric Study.
This 14 weeks longitudinal study will be conducted from March 2018 to June 2020, with a 40 participants. No subjects has received placebo medication at any point in the research procedures.
- Trial name
- NCT03487718
- Testing
- Leukocyte platelet rich fibrin plug + d-PTFE membrane, d-PTFE membrane
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Firas Al Yafi
Pain
A Study to Evaluate the Efficacy and Safety of HR18042 Tablets for Postoperative Analgesia After Impacted Teeth Removal Surgery.
This is a multicenter, randomized, double-blind, dose finding, parallel controlled with active drug and placebo, phase II clinical trial, and the purpose of the study is to evaluate the efficacy and safety of HR18042 tablets for…
- Trial name
- NCT05470075
- Testing
- HR18042 tablets, Tramadol hydrochloride SR Tablets
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Implant Osseointegration, Implant Osteotomy
"Osseodensification Efficacy on Molar Septum Expansion in Immediate Molar Implant Placement
The ideal positioning of immediate implants in molar extraction sockets often requires the osteotomy to be in the interradicular septum, which can be challenging in some cases, with traditional site preparation techniques.
- Conditions
- Implant Osseointegration, Implant Osteotomy, Implant Placement, Implant Primary Stability
- Trial name
- NCT07108361
- Testing
- Osseodensification, conventional drilling
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Orthodontic Brackets, Pain
Erbium-doped Yttrium Aluminum Garnet (Er:YAG) Laser vs Conventional Ceramic Bracket Debonding: A Split-Mouth Clinical Trial
This randomized split-mouth clinical trial evaluates enamel surface preservation, pulpal temperature variation, and patient-reported discomfort during ceramic orthodontic bracket removal using two Erbium-doped yttrium aluminum…
- Conditions
- Orthodontic Brackets, Pain, Temperature Change, Laser
- Trial name
- NCT07517601
- Testing
- Er:YAG Laser - Parameter 1, Er:YAG Laser - Parameter 2, Conventional Mechanical Debonding
- Where
- Lebanon
- Volunteers
- 10 people
- Sponsor
- Saint-Joseph University