Clinical trials: Extraction, Tooth
Dental Caries
Pulp Protection in Selective Carious Tissue Removal
Although selective removal of carious tissue to soft dentin (SRCT-S) has been proposed as the standard of care for the management of deep dentin caries, it is unclear whether a cavity liner is necessary.
- Trial name
- PULPROTECT (NCT04250142)
- Testing
- Self-etching Adhesive, Glass Ionomer
- Where
- Chile
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Talca
Deep Carious Lesions
Clinical Performance of Resin Composite Restoration After Dentin Biomodification by Grape Seed Extract in Deep Carious Lesions.
This study will evaluate the clinical and radiographic performance of resin composite restoration after utilized a grape seed extract as dentin biomodification in vital teeth with deep occlusal carious lesions (ICDAS 5-6) after…
- Trial name
- GSE (NCT06780527)
- Testing
- 15% Grape seed extract as dentin pretreatment
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acute Pain
Efficacy and Safety in a Randomised Acute Pain Study of MR308 (Tramadol/Celecoxib).
The MR308-3501 study is a multicenter, randomised, double-blind, parallel-group study in male and female adult subjects to demonstrate the efficacy of MR308 in the treatment of acute moderate to severe pain after the extraction…
- Trial name
- STARDOM1 (NCT02982161)
- Testing
- MR308, Tramadol
- Where
- 7 sites in Canada, Germany and 4 more
- Volunteers
- 818 people
- Sponsor
- Mundipharma Research GmbH & Co KG
Healthy, Tooth Extraction
Capsaicin to Control Pain Following Third Molar Extraction
Capsaicin to Control Pain Following Third Molar Extraction Summary: This study will test the effectiveness of the drug capsaicin in controlling pain after third molar (wisdom tooth) extraction.
- Trial name
- NCT00088686
- Testing
- Capsaicin (Intramucosal Injection)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Healthy Volunteers
Effect of CYP2C9*3 Polymorphism on Ibuprofen in Pakistani Population
The goal of the study was to identify the effect of CYP2C9 gene polymorphism in the Pakistani population. The main question it aims to answer were: to evaluate the effect of this genetic polymorphism on the clinical efficacy of…
- Trial name
- NCT05983042
- Testing
- Ibuprofen 400 mg
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Riphah International University
Local Infiltration
The Use of Infiltrative Anesthesia Instead of Inferior Alveolar Block
Generally it is accepted that infiltrative anesthesia (IA) is not sufficient for extraction of lower molars and that an inferior alveolar nerve block (IANB) is needed.
- Trial name
- NCT06439186
- Testing
- Lidocain
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Healthy, Maxillary First Premolar Tooth Extraction
Gingival Crevicular Fluid Characterization During Orthodontic Treatment
During Orthodontic tooth movement, teeth are moved through alveolar bone under applied forces. The applied mechanical loading force must be transferred to the alveolar bone via periodontal ligament (PDL).
- Conditions
- Healthy, Maxillary First Premolar Tooth Extraction, Canine Retraction
- Trial name
- NCT04226469
- Testing
- Tooth movement
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Malocclusion, Long Face Syndrome
Effect of Extraction Vs Non-extraction Orthodontic Treatment on Vertical Facial Dimension
The aim of the current clinical trial was to evaluate the effects of premolar extractions compared with non-extraction orthodontic treatment on the skeletal vertical dimension of the face.
- Conditions
- Malocclusion, Long Face Syndrome, Crowding, Tooth
- Trial name
- NCT04151875
- Testing
- Extraction orthodontic treatment, Non-extraction orthodontic treatment
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Extraction Status Nos
Efficacy of Skeletal Anchorage (MINISCREW)
The main objective of the investigators' study is to assess the efficacy of a course of treatment using skeletal anchorage (MINISCREW) as compared with treatment involving dental anchorage (reference) during dentofacial…
- Trial name
- Minivis (NCT01025141)
- Testing
- Skeletal anchorage (MINISCREW), dental anchorage
- Where
- France
- Volunteers
- 99 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alveolar Bone Loss
Ridge Preservation Following Tooth Extraction Using Porcine and Bovine Xenograft Materials
The study is a two-arm, parallel-design, randomized, prospective clinical trial designed to examine histologic wound healing following ridge preservation using bovine xenograft and porcine xenograft materials.This protocol…
- Trial name
- NCT02802319
- Testing
- Porcine Xenograft (Zcore), Bovine Xenograft (Bio-Oss)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Class II Malocclusion
Effect of Upper Third Molar Extraction on Distalization Carriere Motion Appliance :A Prospective Clinical Study
This clinical study will be directed to compare the effect of presence or absence of third molar on distalization of the upper posterior segment by using carriere motion appliance
- Trial name
- NCT05166928
- Testing
- carriere motion appliance
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Extraction
Etoricoxib Versus Ibuprofen in Third Molar Extraction Pain
The aim of this study is to evaluate the analgesic efficacy of etoricoxib compared with a well known and widely used non-steroid antinflammatory drug, ibuprofen, in third molar extraction pain.
- Trial name
- NCT00855777
- Testing
- etoricoxib, ibuprofen
- Volunteers
- 110 people
- Sponsor
- Universita di Verona
Buccal Infiltration Inferior Alveolar Nerve Block Articaine
Comparing Buccal Infiltration and Inferior Alveolar Nerve Block for Extraction of Mandibular Teeth
This study compares the effectiveness of two techniques of local anesthesia in the extraction of mandibular teeth. One group received inferior alveolar nerve block and the other group received buccal infiltration of 4% Articaine
- Trial name
- NCT04294745
- Testing
- Buccal infiltration, Inferior alveolar nerve block
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Dental Caries
Evaluation of Chemo-mechanical Caries Removal Materials in Caries Removal
The evolution of conservative dentistry that adopts the preservation of tooth structure and affected dentin that can remineralize and save the pulp from exposure, in addition to pain and fear that companies' traditional caries…
- Trial name
- NCT05733923
- Testing
- Traditional Escavation, Excavation with Sodium Hypochlorite Gel 2.5%., Excavation with Papacarie Duo
- Where
- Syria
- Volunteers
- 90 people
- Sponsor
- Damascus University
Atrial Fibrillation, Periodontal Disease
Tooth Extraction in Patients With Atrial Fibrillation in Use of New Oral Anticoagulants
The purpose of this study is to evaluate the safety of a protocol which does not suspend the new oral anticoagulants (dabigatran, rivaroxaban and apixaban) in front of dental extractions in patients with non-valvular atrial…
- Conditions
- Atrial Fibrillation, Periodontal Disease, Hemorrhage
- Trial name
- NCT03181386
- Testing
- Rivaroxaban, Dabigatran and Apixaban, Warfarin
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Healthy, Tooth Extraction
Prostanoid Levels After Medication to Prevent Pain Following Third Molar (Wisdom Tooth) Extraction
This study will evaluate how well different medications work to relieve pain following third molar (wisdom tooth) extraction. Scientists believe that hormone-like substances called prostanoids contribute to pain following oral…
- Trial name
- NCT00078104
- Testing
- Extraction of wisdom teeth
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Tooth Extraction Status Nos
Effect of Mucograft® Seal on Post-extraction Ridge Preservation Using Bone Allograft
The objective of this study is to evaluate clinically and radiographically the effect of Mucograft® seal when used for the ridge preservation procedure in combination with Freeze Dried Bone Allograft (FDBA) at the extraction site…
- Trial name
- Mucograft (NCT02697890)
- Testing
- FDBA (MinerOss®) + Mucograft® seal, FDBA (MinerOss®) + Collagen Sponge (HeliPLUG®)
- Volunteers
- 28 people
- Sponsor
- Tufts University
Alveolar Bone Loss
Alveolar Ridge Preservation Techniques After Tooth Extraction
The aim of the present randomized controlled trial (RCT) was to evaluate the efficacy of different alveolar ridge preservation (ARP) techniques on hard tissue dimensional alterations after tooth extraction, based on clinical…
- Trial name
- NCT04934813
- Testing
- Alveolar ridge preservation
- Where
- Greece
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Pain, Acute
Analgesic Effects of Cannabidiol for Simple Tooth Extractions in Dental Patients
The purpose of this study is to evaluate the analgesic effects of cannabidiol for patients who have undergone simple tooth extraction.
- Trial name
- SWAP (NCT04271917)
- Testing
- cannabidiol, acetaminophen 500mg and ibuprofen 200mg combo
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Tennessee
Dental Anxiety
Effectiveness of Auricular Acupuncture in Reducing Dental Anxiety and Pain Perception During Orthodontic Extractions Among Adolescents
This prospective, randomised, double-blinded cross-over study aims to compare the effectiveness of auricular acupuncture (AA) with placebo sham acupuncture (PSA) in reducing dental anxiety, pain perception and physiological…
- Trial name
- NCT06434844
- Testing
- Auricular acupunctures
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong