Clinical trials: Extraction, Tooth
Third Molar Extraction, Oral Pain
Effect of Low Power Laser in the Pain After Lower Tooth Extraction
Introduction: Previously published studies report a prevalence ranging from 35.9% to 58.7% of the general population with at least one impacted wisdom tooth.
- Conditions
- Third Molar Extraction, Oral Pain, Tooth Extraction
- Trial name
- NCT05255731
- Testing
- Low frequency laser activated photobiomodulation, Low frequency laser photobiomodulation inactive
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Caries, Dental
Selective Dentine Removal in Primary Teeth
Background There is little information regarding the longevity of the restored tooth, considering the health of the pulp-dentine complex, in children who do not sufficiently cooperate with dental treatment.
- Trial name
- NCT03872037
- Testing
- Selective removal of carious tissue and restoration with Maxxion, Control
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Periodontal Pocket, Periodontal Bone Loss
Using Xenograft Combined With Barrier Membrane to Improve the Formation of Deep Periodontal Pockets
To evaluate the clinical effect of site preservation after third molars extraction by using tooth extraction of third molars with site preservation using bio-oss and bio-guide in preventing the formation of deep periodontal…
- Conditions
- Periodontal Pocket, Periodontal Bone Loss, Impacted Third Molar Tooth
- Trial name
- NCT06318247
- Testing
- site preservation
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Alveolar Ridge Preservation
Enamel Matrix Derivative for Alveolar Ridge Preservation After Tooth Extraction
The Global Burden of Disease Study of 2016 considered oral disease as the most common noncommunicable disease that affected half of the world population throughout their lifetime.
- Trial name
- NCT05517798
- Testing
- Alveolar ridge preservation
- Where
- United Arab Emirates
- Volunteers
- 34 people
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Bleeding, Pain
Colibricare Efficacy on Oral Surgical Procedures/Extraction Wound and Gingiva Retraction
In this randomized, three-arm trial, 120 patients undergoing wisdoms' extractions were assigned to control (gauze pressure application), commercial sponge, or Coli-sorb® groups.
- Trial name
- NCT07638930
- Testing
- wisdoms' surgical extractions
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Cairo University
Dental Calculus, Gingivitis and Periodontal Diseases
Bio-Descaling Toothpaste for Dental Calculus Reduction
Dental calculus is a calcified mineralized plaque composed primarily of calcium phosphate salts covered by an unmineralized bacterial biofilm layer.
- Conditions
- Dental Calculus, Gingivitis and Periodontal Diseases, Periodontal Diseases
- Trial name
- AntiCal (NCT07689071)
- Testing
- Bio-Descaling Powder (BDP) Toothpaste
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Tooth Loss
Long- Term Follow-up of Extraction Socket Management
Twenty-nine patients needing single tooth replacement in aesthetic area were treated by extraction and socket preservation with saddle connective tissue graft between September 2009 and February 2012.
- Trial name
- NCT03410251
- Testing
- Socket preservation
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Liege
Crowding of Teeth, Malocclusion; Displaced Teeth
Timing, Trajectories and Prediction in Severe Dental Crowding: The Create SPACE (cSPACE)
Dental crowding is the most common malocclusion affecting up to 45% of the population and represents one of the leading reasons for seeking orthodontic treatment.
- Conditions
- Crowding of Teeth, Malocclusion; Displaced Teeth, Malocclusion in Children
- Trial name
- cSPACE (NCT07911176)
- Testing
- Early first premolar extraction with observation, Early first premolar extraction with planned fixed orthodontic treatment
- Volunteers
- 300 people
- Sponsor
- Vastra Gotaland Region
Dental, Dental Extraction
Insomnia and Post-Dental Surgery Pain: A Prospective Study
The purpose of this prospective observational study is to evaluate the relationship between preoperative sleep disturbances-specifically insomnia-and postoperative pain intensity following oral surgical procedures.
- Conditions
- Dental, Dental Extraction, Insomnia
- Trial name
- INDOLC (NCT07712432)
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Impacted Third Molar Tooth
Changes in Resistome After Dental Extraction and Amoxicillin.
The aim of this study is to evaluate the nature of the change in oral and gut bacterial resistance profiles after antibiotic therapy for a surgical procedure in two groups.
- Trial name
- NCT02830347
- Testing
- Amoxicillin, Extraction
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Tooth Loss
Treatment of Post-Extraction Dehisced Socket - A Case Series Study
PURPOSE The purpose of this case series is to clinically, radiographically and histologically evaluate the treatment of dehiscence defects in extraction sockets using a minimally-invasive GBR technique that involves the…
- Trial name
- OSTEO2 (NCT02980211)
- Testing
- Alveolar Ridge Reconstruction
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Gustavo Avila-Ortiz DDS, MS, PhD
Alveolar Ridge Augmentation, Connective Tissue
Ridge Preservation Using Different Techniques
Soft tissue contour and radiographic evaluation of alveolar ridge preservation using different techniques Background: Following tooth extraction, the alveolar ridge undergoes an inevitable remodeling process which influences…
- Conditions
- Alveolar Ridge Augmentation, Connective Tissue, Tooth Extraction, Membranes; Retained
- Trial name
- NCT05892016
- Testing
- Alveolar ridge preservation
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Alveolar Bone Loss, Bone Resorption
Alveolar Management Following Teeth Extraction
Investigation of the volume stability of the alveolar ridge, the bone structure and soft tissue appearance at a delayed dental implantation using two bone substitute materials (1. Human-Spongiosa, gefriergetrocknet, CHB; 2.
- Trial name
- NCT03089619
- Testing
- Human-Spongiosa, collacone®
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- University Medicine Greifswald
Impacted Third Molar Tooth
Extraction of Impacted 3rd Molars, Can Bone Support of the Second Molar be Promoted by a Bio-Oss Graft?
A prospective study examining bilateral 3rd molar extraction, by a split mouth protocol the investigators augment unilaterally and compare periodontal parameters in between.
- Trial name
- NCT02753439
- Testing
- Geistlich Bio Oss
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Tooth Extraction Status Nos, Bone Augmentation
Using Of Chitosan in Alveolar Ridge Preservation
The goal of this clinical trial is to assess the efficacy of chitosan as a socket preservation material after tooth extraction in compare to the standard treatment.
- Trial name
- NCT06140277
- Testing
- extraction with chitosan particles as a replacement for bone graft with collagen membrane, extraction with placing of allograft particles with collagen membrane, tooth extraction only
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Prince Sattam Bin Abdulaziz University
Tooth Extraction, Bone Graft
Resorbable vs Non-resorbable Bone Substitute at Immediate Post-extractive Single Implants
This study compares two bone graft materials used when placing a dental implant right after tooth removal. One graft fully dissolves (GTO®), the other only partly (Apatos®).
- Conditions
- Tooth Extraction, Bone Graft, Alveolar Bone Loss, Dental Implant
- Trial name
- NCT07047131
- Testing
- GTO® (fully resorbable bone substitute), Apatos® (partially resorbable bone substitute)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Marco Esposito
Caries, Dental
Partial Caries Removal in Permanent Molars Restored Using Giomer
Dental manufacturers\' constant tweaks and improvements to composite compositions have resulted in a wider spectrum of restorative materials with positive long-term clinical performance.
- Trial name
- NCT06601972
- Testing
- Beautifil II LS (Low-Shrinkage), Nanohybrid resin composite
- Volunteers
- 122 people
- Sponsor
- NewGiza University
Healthy Volunteers
Effect of CYP2C9*3 Polymorphism on Ibuprofen in Pakistani Population
The goal of the study was to identify the effect of CYP2C9 gene polymorphism in the Pakistani population. The main question it aims to answer were: to evaluate the effect of this genetic polymorphism on the clinical efficacy of…
- Trial name
- NCT05983042
- Testing
- Ibuprofen 400 mg
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Riphah International University
Dental Caries
Selective Caries Removal (SCR) Versus Pulpotomy in Preventing Pulp Necrosis and Apical Periodontitis
The study design is a randomized controlled trial and up to 120 teeth, 50 in each of the 2 groups, will be enrolled from the patients at the National University Centre for Oral Health Singapore (NUCOHS) Endodontic unit.
- Trial name
- NCT04672070
- Testing
- Selective Caries Removal, Pulpotomy
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Dental Pain
Evaluation of the Efficacy and Safety of Diclofenac HPBCD 75mg/ml in Treatment of Pain Following Dental Surgery
The present study is aimed at demonstrating the therapeutic equivalence of diclofenac HPBCD 75mg/1ml s.c. with the marketed reference product, Voltarol® 75mg/3ml i.m.
- Trial name
- NCT00943098
- Testing
- Diclofenac HPBCD s.c. 75mg/ml, Voltarol 75mg/3ml i.m.
- Where
- 3 sites in United Kingdom
- Volunteers
- 142 people
- Sponsor
- IBSA Institut Biochimique SA