Clinical trials: Extraction, Tooth
Wound Heal
Effect of A-PRF After Removal of Wisdom Teeth
To evaluate the healing effect of advanced platelet-rich fibrin (blood clot charged with growth factors) taken from the patient own blood on the extraction site.
- Trial name
- A-PRF (NCT03703479)
- Testing
- autologous blood clot made from the patient own clot without any additive
- Where
- Saudi Arabia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Alveolar Bone Loss
Alveolar Ridge Preservation Techniques After Tooth Extraction
The aim of the present randomized controlled trial (RCT) was to evaluate the efficacy of different alveolar ridge preservation (ARP) techniques on hard tissue dimensional alterations after tooth extraction, based on clinical…
- Trial name
- NCT04934813
- Testing
- Alveolar ridge preservation
- Where
- Greece
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Tooth Extraction
Evaluation of β-tricalcium Phosphate/Calcium Sulfate Versus Allografts
Thirty healthy patients will be selected from the outpatient clinic of the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University, to be included in this study with non-restorable posterior…
- Trial name
- NCT05708196
- Testing
- Alloplast bone grafting material (EthOss, Ethoss Regeneration Ltd, Silsden, UK)., Allograft bone grafting material.
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Tooth Extraction
Tranexamic Acid To Reduce Bleeding in Patients Treated With New Oral Anticoagulants Undergoing Dental Extraction
In patients treated with direct oral anticoagulants, bleeding events during or after tooth extraction can lead to unscheduled interruption of the antithrombotic treatment and a potential increased risk of thrombo-embolic events.
- Trial name
- EXTRACT-NOAC (NCT03413891)
- Testing
- Tranexamic Acid
- Where
- Belgium
- Volunteers
- 222 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pain (Visceral, Somatic, or Neuropathic)
Comparison of Conventional Buccal Nerve Block Versus Buccal Nerve Trunk Block During Extraction of Posterior Mandibular Teeth
This randomised control trial will compare the efficacy of conventional buccal nerve block versus buccal trunk block using visual analogue scale to evaluate pain and additional anesthesia injection during extraction of mandibular…
- Trial name
- Buccal Trunk (NCT07330518)
- Testing
- Conventional Buccal Nerve Block, Buccal Nerve Trunk Block
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Watim Medical & Dental College
Alveolar Ridge Augmentation, Connective Tissue
Ridge Preservation Using Different Techniques
Soft tissue contour and radiographic evaluation of alveolar ridge preservation using different techniques Background: Following tooth extraction, the alveolar ridge undergoes an inevitable remodeling process which influences…
- Conditions
- Alveolar Ridge Augmentation, Connective Tissue, Tooth Extraction, Membranes; Retained
- Trial name
- NCT05892016
- Testing
- Alveolar ridge preservation
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Wisdom Teeth
Different Inflammatory Biomarkers With Surgical Removal of Mandibular Third Molars
Removal of mandibular third molars (M3s) is the most frequently performed surgical intervention undertaken in dentistry. The indications and timing of surgical removal of M3s has been a matter of international and national…
- Trial name
- NCT05962593
- Testing
- Telephone call
- Where
- Denmark
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Decayed Teeth
Effect of Bone Marrow Mononuclear Cell Layer Seeded on Platelet-rich Fibrin on an Alveolar Socket After Extraction
Bone marrow aspiration from maxillary tuberosity will be centrifuged to separate the bone marrow mononuclear cell layer using the density gradient separation method, then it will be seeded in a platelet-rich fibrin membrane and…
- Trial name
- NCT05465421
- Testing
- bone marrow aspiration from maxillary tuberosity and BMMNCs separation to be seeded on PRF and used for socket preservation
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy, Tooth Extraction
Pain Pathways in the Brain
This study will evaluate brain pathways involved in feeling pain and pain relief following administration of pain medication. Magnetic resonance imaging (MRI) will be used to measure brain activity at sites that become more…
- Trial name
- NCT00078364
- Testing
- MRI
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Dental Pain
Phase 2 Study of Indomethacin Capsules to Treat Dental Pain
The purpose of this study is to determine whether Indomethacin Test Formulation Capsules are safe and effective for the treatment of dental pain.
- Trial name
- NCT00964431
- Testing
- Celecoxib 400 mg, Indomethacin Test (lower dose), Indomethacin Test (upper dose)
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Bone Graft, Tooth Extraction
Ridge Preservation With FDBA (Freeze Dried Bone Allograft) Using Dexamethasone vs. Saline
Following the removal of a tooth, a bone graft is often placed in the socket to try to maintain the volume of bone that was there when the tooth was present so that the bone does not "shrink".
- Trial name
- NCT06556095
- Testing
- Dexamethasone 4mg/ml solution
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Dental Implants
Study on Immediate Loading of Immediately Placed Single Implants.
The purpose of this study is to evaluate survival and success rates of dental implants placed with immediate loading protocol in extraction sockets. All patients were monitored for 1 year after implants placement.
- Trial name
- NCT01107600
- Testing
- Immediate implant and socket preservation
- Where
- 2 sites in Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital San Pietro Fatebenefratelli
Postoperative Pain
Postoperative Pain After the Removal of Root Canal Filling Material
The aim of this study was to evaluate the intensity and duration of postoperative pain after the removal of root canal filling material in retreatment procedures of upper incisor teeth with chronic apical periodontitis, using…
- Trial name
- NCT02905773
- Testing
- root canal therapy, root canal retreatment
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Tooth Extraction
Ridge Preservation Using FDBA and a Collagen Wound Dressing in Molar Sites
Currently, it is not known what the dimensional changes might be following a molar site extraction which has been grafted with FDBA and covered with a collagen wound dressing.
- Trial name
- NCT03191448
- Testing
- Ridge preservation, FDBA, Collagen wound dressing
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Extraction of Third Molar Teeth
Perioperative Acupuncture for Impacted Mandibular Third Molar Extractions
This is a double-blinded, randomized, controlled study on the effect of perioperative acupuncture on pain after third molar extraction.
- Trial name
- NCT02498184
- Testing
- acupuncture
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
Dental Anxiety, Pain Management
Effectiveness of Virtual Reality Technique on Children
Studying the effect of using virtual reality technique in managing pain, anxiety, and vital signs among pediatric dental patients.
- Conditions
- Dental Anxiety, Pain Management, Pediatric Dentistry
- Trial name
- NCT07722221
- Testing
- Conventional, Virtual reality
- Where
- Syria
- Volunteers
- 64 people
- Sponsor
- Latakia University
Wisdom Teeth, Wisdom Teeth Extraction or Jaw Implant
NeuroCuple to Mitigate Post-Wisdom Teeth Extraction Opioid Risks
This is a randomized (1:1), placebo-controlled clinical trial that will examine the feasibility and effectiveness of a 2-day application of the NeuroCuple device for pain relief and reduction of opioid use following wisdom teeth…
- Trial name
- NCT07461506
- Testing
- NEUROCUPLE™ Patch
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- nCap Medical
Hemostasis, Wound Closure
Effective Hemostasis: An Analysis of Hemostatic Sponges Used in Extraction Procedures
Tooth extraction is a common dental procedure, where hemostasis is crucial for patient recovery. This study evaluates the effectiveness of hemostatic sponges in controlling bleeding and promoting postoperative healing.
- Conditions
- Hemostasis, Wound Closure, Pain, Extraction Socket Healing
- Trial name
- NCT07529106
- Testing
- Hemostatic sponge post tooth extraction
- Where
- Paraguay
- Volunteers
- 30 people
- Sponsor
- Universidad Nacional de Caaguazu
Anxiety and Fear, Tooth Disease
Virtual Reality Used During Tooth Extraction and Extirpation Treatment
This study carriy out to evaluate the effect of virtual reality glasses used during tooth extraction and extirpation treatment under local anesthesia on anxiety and fear in children aged 7-10 years.
- Trial name
- NCT06315816
- Testing
- virtual reality glasses used during tooth extraction and extirpation treatment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Murat Bektaş
Impacted Third Molar Tooth
Topical Arnica and Mucopolysaccharide Polysulfate on Postoperative Pain, Edema and Trismus
The present study was to evaluate the effect of topical Arnica and MPSP application with respect to visual analogue scale (VAS) scores, maximal interincisal opening (MIO) and edema values after mandibular impacted third molar…
- Trial name
- NCT04534426
- Testing
- : Arnica montana, Mucopolysaccharide polysulfate, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University