Clinical trials: Extrapyramidal Symptoms
Paraparesis, Tetraparesis
Prospective Cohort Follow-up of French Patients With Profound and Multiple Disabilities: Healthcare Pathways and Quality of Life Among Patients and Their Families
The studies conducted so far concerning the medical and paramedical cares provided to patients with profound and multiple disabilities (PMD) often show important limitations: samples are too small or very heterogeneous, generally…
- Conditions
- Paraparesis, Tetraparesis, Hemiparesis, Ataxia
- Trial name
- Eval-PLH (NCT02400528)
- Testing
- quality of life questionnaires
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Delirium
A Double-blind, Randomized, Controlled Trial of Quetiapine Versus Haloperidol for the Treatment of Delirium
The purpose of this study is to determine whether quetiapine, and haloperidol are effective and safe in the treatment psychiatric symptoms in patients with delirium.
- Trial name
- QHdelirium (NCT00954603)
- Testing
- quetiapine, haloperidol
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Chiang Mai University
Extrapyramidal Symptoms, Drug-induced Parkinsonism
A Computer-Assisted Tool for Objective Assessment of Extrapyramidal Symptoms
This prospective, single-center observational study aims to develop and validate a computer-assisted tool for the objective quantitative assessment of extrapyramidal symptoms (EPS).
- Conditions
- Extrapyramidal Symptoms, Drug-induced Parkinsonism, Akathisia, Drug-Induced, Tardive Dyskinesia (TD)
- Trial name
- NCT07715994
- Testing
- Computer-Assisted Objective Assessment of Extrapyramidal Symptoms
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Nausea, Extrapyramidal Symptoms
The Montefiore Metoclopramide Study
Metoclopramide is a dopamine antagonist frequently used for the treatment of nausea, vomiting, and migraine headaches in Emergency Departments.
- Trial name
- NCT00475306
- Testing
- metoclopramide 10 mg, Diphenhydramine 25 mg, Metoclopramide 20 mg
- Where
- United States
- Volunteers
- 289 people
- Sponsor
- Montefiore Medical Center
Parkinsonism, Tremor
TRANSPARK_LONG: The Diagnostic Value of Early Transcranial Ultrasound in Patients With Extrapyramidal Diseases in a Swedish Population
Popular science summary of the project The purpose of the study is to investigate in a Swedish population how well the investigators' previous ultrasound findings match the final diagnosis (PD, APS or ET) after a particularly…
- Conditions
- Parkinsonism, Tremor, Dementia
- Trial name
- NCT06032585
- Where
- Sweden
- Volunteers
- 74 people
- Sponsor
- Region Skane
Tardive Dyskinesia
The Assessment of Movement Disorders Utilizing Live Two-Way Video
The purpose of this project is to determine the equivalency of extrapyramidal symptoms (EPS) and tardive dyskinesia (TD) examinations conducted via live two-way video versus live examinations completed in-person
- Trial name
- NCT01467089
- Testing
- Two way video assessment
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Northwell Health
Extrapyramidal Syndrome
a Pilot Study of Pramipexole to Treat Extrapyramidal Symptoms Induced by Antipsychotics
This study is a pilot phased interventional clinical trial . The first stage will recruit 10 patients with antipsychotic induced extrapyramidal symptoms.The patients will take pramipexole for 8 weeks.
- Trial name
- NCT03430596
- Testing
- Pramipexole, Trihexyphenidyl hydrochloride
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Mental Health Center
Schizophrenia
Adjuvant Therapy With Pergolide in Treating Cognitive Deficits in Schizophrenia
The objective of this study is to compare the modulation of pergolide, a D1/D2 receptor agonist, to placebo in non-acute schizophrenic subjects under concomitant therapy with atypical antipsychotics on specific PFC functions.
- Trial name
- NCT01066403
- Testing
- Pergolide
- Where
- 4 sites in Germany
- Volunteers
- 28 people
- Sponsor
- Heidelberg University
Pharmacogenetics, Healthy
Typical Versus Atypical Antipsychotics; Occupation of Striatal Receptors and the Appearance of Extrapyramidal Symptomatology, in Healthy Volunteers
The purpose of this study is to determine in healthy volunteers treated with typical or atypical antipsychotics -AP-, the relationship between genetic polymorphisms in cytochrome genes CYP2D6 (*3, *4, *5, *6 and Nxn) and CYP3A5…
- Trial name
- APSEP (NCT01259973)
- Testing
- Risperidone, Haloperidol
- Where
- 2 sites in Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona