Clinical trials: Extremity
Upper Extremity Injury
Infraclavicular Brachial Plexus Block With Bupivacaine Alone or With Both Dexmedetomidine and Dexamethasone
Upper-extremity regional anesthetic techniques, using brachial plexus blockade, have been shown to reduce adverse effects related to opioid administration, improve patient satisfaction, and provide significantly improved…
- Trial name
- NCT06356415
- Testing
- Bupivacaine injection, Bupivacaine+ Dexamethasone+ Dexmedetomidine
- Volunteers
- 40 people
- Sponsor
- Suez Canal University
Basal Cell Carcinoma (BCC)
Intralesional Cryosurgery for Basal Cell Carcinoma - a Feasibility Study
A feasibility study for the treatment of Basal Cell Carcinoma of the lower extremities in the elderly utilizing intralesional cryosurgery.
- Trial name
- NCT01633515
- Testing
- Intralesional cryotherapy
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Carmel Medical Center
Tibial Fractures, Lower Extremity Fracture
Blood Flow Restriction Training in Patients With Lower Extremity Fractures
This study will look at the effect of using a blood flow restriction device during low load strengthening exercises on patients with tibial shaft fractures, compared to patients performing exercise without the device.
- Trial name
- NCT06496035
- Testing
- Blood Flow Restriction with low load exercise, Therapeutic Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Critical Limb Ischemia (CLI)
IBS Titan vs. PTA in Patients With Infrapopliteal Arterial Stenosis or Occlusive Disease
A prospective, multi-center, randomized trial to assess the safety and effectiveness of Sirolimus-eluting Iron Bioresorbable Peripheral Scaffold System (IBS Titan™) in treating patients with infrapopliteal arterial stenosis or…
- Trial name
- GENIUS (NCT04849325)
- Testing
- Sirolimus-eluting Iron Bioresorbable Peripheral Scaffold System (IBS Titan™), Percutaneous Transluminal Angioplasty (PTA) Device
- Where
- 29 sites in China
- Volunteers
- 120 people
- Sponsor
- Biotyx Medical (Shenzhen) Co., Ltd.
Stroke, Ischemic, Smartpose
The Effect of Rehabilitative Games With SmartPose on Upper Extremity Recovery in Stroke Patients
The goal of this clinical trial is to investigate the effects of SmartPose games on upper extremity motor, functional, and sensory recovery in patients with stroke.
- Conditions
- Stroke, Ischemic, Smartpose, Telerehabilitation
- Trial name
- NCT06778525
- Testing
- Exercise, SmartPose
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul University - Cerrahpasa
Critical Limb Ischemia
UT-15C SR in the Treatment of Critical Limb Ischemia
This study will evaluate UT-15C sustained release tablets in subjects experiencing ischemic lower limb rest pain related to advanced peripheral arterial disease.
- Trial name
- NCT00445159
- Testing
- UT-15C SR (treprostinil diethanolamine) 1mg oral tablets
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Southern Arizona Vascular Institute
Osteomyelitis of Lower Extremities
Osteomyelitis Multi-center Prospective Cohort Study
To establish a prospective, multicenter, real-world cohort of patients with osteomyelitis, by systematically collecting and analyzing detailed treatment and follow-up data, in order to provide clinical evidence for the…
- Trial name
- NCT07251374
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Southwest Hospital, China
Chronic Pain, Pain, Chronic
APM in the Evoke SCS System to Program Patients With Chronic Pain of the Trunk and/or Limbs
Study to evaluate the use of the Assisted Programming Module (APM) in the Evoke Spinal Cord Stimulation (SCS) System to program patients with chronic pain of the trunk and/or limbs.
- Trial name
- APM (NCT06057480)
- Testing
- Evoke Spinal Cord Stimulation System
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- Saluda Medical Pty Ltd
Knee Osteoarthritis
The Effect of Osteopathic Manual Therapy on Vascular Supply
The purpose of this study is to determine if the use of osteopathic manual therapy can influence the vascular supply to the knee, knee range of motion, balance and knee pain, in a group of subjects with knee osteoarthritis.
- Trial name
- NCT01020591
- Testing
- Osteopathic evaluation, Osteopathic evaluation with treatment
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Nova Scotia Health Authority
Stroke, Chronic Stroke Patients
The Effect of Mirror Therapy on Upper Extremity Motor Function in Stroke Rehabilitation
The study aimed to determine the effect of mirror therapy versus conventional physical therapy treatment in improving upper extremity impairments and motor function among chronic hemiplegic subjects. Research Objectives: 1.
- Conditions
- Stroke, Chronic Stroke Patients, Hemiplegia
- Trial name
- MT (NCT06698380)
- Testing
- Conventional Physical Therapy, Mirror Therapy
- Where
- Saudi Arabia
- Volunteers
- 38 people
- Sponsor
- University of Jazan
Regional Anesthesia Success
Paravertebral Block With Brachial Plexus Block for Upper Arm Arteriovenous Fistula Surgery
The primary goal of this quality improvement project is to find the optimal surgical conditions for patients undergoing upper arm arteriovenous graft surgery.
- Trial name
- NCT04720079
- Testing
- Subcutaneous infiltration of intercostobrachial nerve, T2 paravertebral nerve block
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of North Carolina, Chapel Hill
Neuromodulation, Lower Limb
Analysis of Neuromodulation as a Complementary Treatment to Evidence-based Clinical Intervention in Subjects With Musculoskeletal Pathology of the Lower Limb: a Double-blind Randomized Clinical Trial
This project aims to analyze the use of neuromodulation within a treatment protocol for musculoskeletal conditions of the lower limb, as well as to determine the difference between two and three sessions per week.
- Conditions
- Neuromodulation, Lower Limb, Musculoskeletal Disorders
- Trial name
- NCT07165379
- Testing
- Neuromodulation, Physical Exercise, Stretching
- Volunteers
- 64 people
- Sponsor
- University of Malaga
Amputation, Lower Limb Amputation Above Knee (Injury)
Evaluation of a Microprocessor-controlled Prosthetic Knee-ankle System (SPCM)
The main aim of this study is to compare the adaptation capabilities of the microprocessor-controlled knee-ankle prosthesis system with the comparator covered by the French LPPR, known as the "usual prosthesis".
- Trial name
- SPCM (NCT06522646)
- Testing
- SPCM, Usual Prothesis
- Where
- 4 sites in France
- Volunteers
- 12 people
- Sponsor
- Institution Nationale des Invalides
Lower Limb Amputation Below Knee
Automatic Prosthetic Foot Stiffness Modulation to Improve Balance
The goal of this clinical trial is to identify prosthesis stiffness that optimizes balance control in individuals with below knee amputations.
- Trial name
- OSA (NCT06711588)
- Testing
- As-prescribed stiffness, Two categories stiffer than the as-prescribed stiffness, Two categories less stiff than the as-prescribed stiffness
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Limb-girdle Muscular Dystrophy
A Trial to Learn More About an Experimental Gene Therapy Called Bidridistrogene Xeboparvovec (SRP-9003) as a Possible Treatment for Limb Girdle Muscular Dystrophy 2E/R4
This is a multicenter, global study of the effects of a single systemic dose of SRP-9003 on beta-sarcoglycan (β-SG) gene expression in participants with limb-girdle muscular dystrophy, type 2E/R4 (LGMD2E/R4).
- Trial name
- EMERGENE (NCT06246513)
- Testing
- SRP-9003, Glucocorticoid
- Where
- 10 sites in United States, Belgium and 4 more
- Volunteers
- 17 people
- Sponsor
- Sarepta Therapeutics, Inc.
Limb Injury
Pain Reduction for Limb Injuries in Pediatric Emergency Departments: Intranasal Fentanyl or Intranasal Ketamine vs Oral Morphine
The purpose of this study is to determine if IN fentanyl (1.5 µg/kg) or IN ketamine (1 mg/kg) is more effective at 30 minutes than oral morphine (0.5 mg/kg) in reduction of moderate and severe pain associated with limb injuries…
- Trial name
- ANTAMIN (NCT06464146)
- Testing
- Morphine, IN fentanyl, IN ketamine
- Where
- 5 sites in France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke
Safety Study of Thermal Stimulation on Upper Extremity Motor Recovery to Stroke
Improving upper extremity movement and function in patients with stroke has been one of the primary goals for patients and rehabilitation professionals.
- Trial name
- NCT01078727
- Testing
- A custom-made constant temperature thermal stimulation system (FIRSTEK, Model-B401L, B-300, local company, Taiwan).
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Spastic Diplegia
Arm Ergometer Versus Stabilization Exercises on Trunk Control and Upper Extremity Functions in cp
The purposes of the current study are to: Define and compare between the efficacy of arm ergometer versus stabilization exercises on trunk control, hand grip power and upper limb quality of functions in children with diplegia.
- Trial name
- NCT05032703
- Testing
- Arm ergometer
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Diabetes Mellitus, Chronic Ulcers of the Lower Limb
Hyperbaric Oxygen Therapy (HBOT) for Chronic Diabetic Lower Limb Ulcers
The purpose of this study is to determine if HBOT plus standard wound care is more effective than standard wound care alone at preventing the need for major amputation (metatarsal and up) in patients with diabetes mellitus (Type…
- Trial name
- HBOT (NCT00621608)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Canada
- Volunteers
- 107 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Sarcoma
Radiation Therapy With or Without SU5416 in Treating Patients With Soft Tissue Sarcoma
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as SU5416 may stop the growth of cancer by stopping blood flow to the tumor.
- Trial name
- NCT00023725
- Testing
- semaxanib, conventional surgery, radiation therapy
- Where
- 226 sites in United States, Canada
- Sponsor
- Radiation Therapy Oncology Group