Clinical trials: Extremity Injuries Lower
Anesthesia, Hip Fractures
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
The ANDES Platform Trial is a pragmatic, multicenter, adaptive randomized controlled platform trial in patients aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Anesthesia, Hip Fractures, Dementia, Cognitive Impairment
- Trial name
- ANDES platform (NCT06452147)
- Testing
- Nerve block, Standard anesthesia care, Bupivacaine liposome
- Where
- 13 sites in China
- Volunteers
- 1,860 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Unstable Trochanteric Fractures
Proximal Femoral Nail Antirotation™ (PFNA) Versus Gamma Nail 3™ (Gamma3) for Intramedullary Nailing of Unstable Trochanteric Fractures
The purpose of this study is to compare rates of any fracture fixation complication and revision rates after intramedullary fixation of unstable trochanteric fractures between the Proximal Femoral Nail Antirotation™…
- Trial name
- PROGAINT-ES (NCT00736684)
- Testing
- Proximal Femoral Nail AntirotationTM (PFNA), Gamma Nail 3TM (Gamma3)
- Where
- 6 sites in Spain
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Taping, Ankle Sprains
The Immediate Effects of Applying Dynamic Tape, Kinesio Tape and Sport Tape With Chronic Ankle Instability
Injuries to the ankle joint account for 20% of the population that is afflicted with joint injury and the largest percentage of self-reported musculoskeletal injuries (> 10%) are to the ankle.
- Trial name
- NCT03815526
- Testing
- Dynamic tape, Kinesio tape, Sport tape
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Ankle Injuries
Lateral Ankle Sprain and Platelet Rich Plasma
Lateral ankle sprains are one of the most common in sports medicine. Considering the sprains in general, they represent an 85% of the ankle lesions. The incidence in high performance athletes range from 16 to 21%.
- Trial name
- NCT02609308
- Testing
- Short leg cast, Platelet-rich plasma
- Where
- Mexico
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Nuevo Leon
Tibial Fractures, Lower Extremity Fracture
Blood Flow Restriction Training in Patients With Lower Extremity Fractures
This study will look at the effect of using a blood flow restriction device during low load strengthening exercises on patients with tibial shaft fractures, compared to patients performing exercise without the device.
- Trial name
- NCT06496035
- Testing
- Blood Flow Restriction with low load exercise, Therapeutic Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Ankle Injuries
Turkish Version of the Ankle Instability Instrument
This study aimed to translate the Ankle Instability Instrument into Turkish language, to perform a cultural adaptation study and to evaluate its validity and reliability in the Turkish population.
- Trial name
- NCT04816058
- Testing
- Determining the level of ankle instability
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Patellar Dislocation
Comparison of Two Graft Choices in Mediale Patellofemoral Ligament Reconstruction (MPFL)
The purpose of this study is to elucidate surgical techniques for reconstructing MPFL in the treatment of chronic patella instability.
- Trial name
- NCT05706363
- Testing
- Quadriceps graft
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Leg Injuries
Smart Phone as a Screening and Evaluation Tool to Identify Knee Valgus During Dynamic Activities
Evidence supports the use of two dimensional video analysis to assess the presence of dynamic knee valgus during generally used screening tasks, however there is limited evidence to support the use of the various smart phone…
- Trial name
- NCT02167399
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mitchell Selhorst
Muscle Atrophy, Surgery
Use of Testosterone to Prevent Post-Surgical Muscle Loss - Pilot Study
The loss of muscle mass post-surgery confounds recovery efforts and leads to a delay in patient's ability to return to activities.
- Conditions
- Muscle Atrophy, Surgery, Knee Injuries and Disorders, Complication of Surgical Procedure
- Trial name
- NCT04456530
- Testing
- Aveed 750 MG in 3 ML IM Injection, Normal Saline 3 ML IM Injection
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The Stone Research Foundation for Sports Medicine and Arthritis
ACL - Anterior Cruciate Ligament Rupture, Activation Failure
Activation Failure of Knee Extensors After Anterior Cruciate Ligament Rupture Depending on the Contraction Mode
The primary objective of the study is to evaluate the impact of ACL injury and ACL reconstruction on voluntary activation during maximal voluntary contraction (measured by neurophysiological parameters) according to the…
- Conditions
- ACL - Anterior Cruciate Ligament Rupture, Activation Failure, Contraction Mode
- Trial name
- QUADFAIL (NCT06783062)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- La Tour Hospital
Muscle Atrophy, Muscle Weakness
Evaluating Muscle Function After Ankle Surgery
Patients who are forced to rest or reduce activity as a result of illness, injury, or surgery often experience resulting muscle weakness.
- Conditions
- Muscle Atrophy, Muscle Weakness, Fractures
- Trial name
- NCT00060970
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Arthropathy of Knee, Osteo Arthritis Knee
Meditation and Opioid Consumption in Total Joint Replacement Patients Undergo Primary Total Hip and Knee Replacement
The main purpose of this study is to look at whether meditation techniques can help reduce pain and opioid use after surgery.
- Conditions
- Arthropathy of Knee, Osteo Arthritis Knee, Osteonecrosis, Meditation
- Trial name
- NCT05669066
- Testing
- Mindful meditation
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Fracture Pelvis
Comparison Between Dexamethasone and Dexmedetomidine in Spinal Anesthesia for Cases With Fracture Pelvis Fixation
The aim of this study is to compare dexamethasone and dexmedetomidine as adjuvant to bupivacaine in fracture pelvis fixation as regard duration of sensory block and postoperative pain management.
- Trial name
- NCT07485127
- Testing
- 60 patients will be involved, half patients will receive 13mg bupivacaine + 4 mg dexamethasone. The other half will receive 13mg bupivacaine + 4 mg dexmedetomidine. All will be monitored closely.
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Patella, Joint Instability
Development of a Test Battery for Measurement of Knee Function in Patients With Patellar Instability
About six months after patella stabilizing surgery postoperative restrictions are commonly lifted and patients may consider whether a return to activity/sports is feasible.
- Conditions
- Patella, Joint Instability, Patellofemoral Joint Dislocation
- Trial name
- NCT05119088
- Testing
- Return to Sport testbattery
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Haraldsplass Deaconess Hospital