Clinical trials: Extremity Injury
Tibial Fractures, Lower Extremity Fracture
Blood Flow Restriction Training in Patients With Lower Extremity Fractures
This study will look at the effect of using a blood flow restriction device during low load strengthening exercises on patients with tibial shaft fractures, compared to patients performing exercise without the device.
- Trial name
- NCT06496035
- Testing
- Blood Flow Restriction with low load exercise, Therapeutic Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Muscle Atrophy, Proximal, Muscle Atrophy
Ultrasound for Rectus Femoris Measurement
Postoperative protocols for orthopedic procedures on the lower limb often require a period of immobilization to protect the surgical site.
- Conditions
- Muscle Atrophy, Proximal, Muscle Atrophy, ACL Tear, Quadriceps Muscle Atrophy
- Trial name
- NCT04105816
- Testing
- 892.1550 Ultrasonic pulsed doppler imaging system, Thigh circumference measurement
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Robert Westermann
Athletic Injuries
Validity of an Upper Extremity Physical Performance Test Battery in Healthy Athletes
This project comprises two studies; a cross-sectional study and a prospective study. 1. The cross-sectional study aims to develop and validate a new sport-specific test battery (PROMs, analytical and physical performance tests)…
- Trial name
- VAL_PPT_H (NCT06153121)
- Testing
- Physical performance test - Closed Kinetic Chain Upper Extremity Stability Test (CKCUEST), Physical performance test - modified Closed Kinetic Chain Upper Extremity Stability Test (m-CKCUEST), Physical performance test - Seated Seated Single Arm Shot Put Test (SSASPT)
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Ghent
Wound of Skin, Non-melanoma Skin Cancer
Efficacy and Safety of a Nanofat-seeded Biological Scaffold in Healing Lower Limb Surgical Defects
Large full-thickness skin defects, such as those resulting from trauma, large and giant congenital nevi, disfiguring scars, or tumor resection remain major clinical problems to patients and physicians.
- Conditions
- Wound of Skin, Non-melanoma Skin Cancer, Skin Graft Complications, Wound of Lower Leg
- Trial name
- NCT03548610
- Testing
- Nanofat-seeded biological scaffold on surgical defect
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Carpal Tunnel Syndrome
Musculoskeletal Health of the Upper Extremity in Emerging Health Professionals
Carpal tunnel syndrome is the most expensive upper extremity work-related musculoskeletal disorder, impacting 10 million people annually and costing employers up to $113,695 per incident.
- Trial name
- NCT02587897
- Testing
- Academic Coursework, Work-Related Hand Activities
- Where
- 3 sites in United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Lower Limb Amputation Knee, Lower Limb Amputation Below Knee (Injury)
Validity and Reliability of The 3-Meter Backward Walk Test in Individuals With Lower Limb Amputation
Clinicians are routinely required to make decisions about fall risk among lower limb prosthesis users. For these decisions, clinicians should use valid, reliable, quantitative, and multidimensional measures of balance test for…
- Trial name
- NCT05095584
- Testing
- 3 meter backward walk test
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tezel Yıldırım Şahan
Subacromial Impingement Syndrome
Investigation of the Effectiveness of Core Stabilization Training in Patients With Subacromial Impingement Syndrome
Subacromial Impingement Syndrome (SIS) is one of the most common shoulder problems. The core region is considered a kinetic link that facilitates the transfer of torque and angular momentum between the upper and lower extremities…
- Trial name
- NCT05966298
- Testing
- Core stabilization training, Standart Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Lower Extremity Injuries
Prediction of Lower Extremity Injuries Using Lower Limb-worn Inertial Measurement Units
This study analyses questionnaires and inertial sensor data from 108 sports science students regarding previous lower extremity injuries, sports activity, and preventive measures, combined with the prospective development of an…
- Trial name
- PredKnee (NCT07289828)
- Testing
- IMU Data collection, Questionnaire
- Where
- Germany
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Wound Heal, Wound Dehiscence
CiNPWT Lower Extremity Amputations (Closed Incision Neagtive Pressure Wound Therapy)
The objective of this study is to evaluate prospectively the effect of a novel application of Closed Incision Negative Pressure Wound Therapy(CiNPWT), as delivered by the V.A.C.
- Trial name
- CiNPWT (NCT06493539)
- Testing
- Standard of Care group, CINPWT
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Southern California
Patellofemoral Pain Syndrome, Exertional Lower Leg Pain
Prevention of Injuries by an Exercise Program - a RCT
Overuse injuries are a major concern for physical active individuals. Study hypothesis is that an exercise programme based on known intrinsic risk factors can prevent overuse injuries in soldiers undergoing basic military…
- Trial name
- NCT00348647
- Testing
- physical training program to prevent injuries
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Amager Hospital
Paraplegia, Upper Limb Pain
Adjusting Wheelchair Set-Up to Minimize Shoulder Joint Forces During Propulsion
Individuals who use a manual wheelchair depend upon their upper limbs to provide a means of locomotion during completion of their activities of daily living.
- Trial name
- NCT00785278
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Surgical Wound, Wound Heal
Evaluating the Outcomes for Incisional Application of Negative Pressure for Nontraumatic Amputations
The purpose of this study is to evaluate how well subjects heal after surgery who receive standard dressings or incisional negative pressure wound therapy for non-traumatic amputation sites.
- Conditions
- Surgical Wound, Wound Heal, Amputation
- Trial name
- NCT03250442
- Testing
- PrevenaTM Device, Standard Dry Dressing
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Burns, Gait Training
Gait Training in Patients With Burn Injury
Twenty-four individuals with burn injury will be included in this study. Participants with burn injury will evaluate with the following assessment tools: Demographic datas; age, gender, height, body mass index; burn…
- Conditions
- Burns, Gait Training, Physical Functions
- Trial name
- NCT03217526
- Testing
- Gait Training
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Phantom Limb
Virtual Integrated Environment in Decreasing Phantom Limb Pain
The purpose of this study is to determine if observing a virtual arm decreases phantom limb pain (PLP) in upper extremity amputees.
- Trial name
- VIE (NCT01462461)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Amputation, Traumatic, Phantom Sensation
Investigating The Effect of Phantom Sensation on Gait in Individuals With Unilateral Below-Knee Amputation
Amputation is a problem that can be encountered for many reasons, can cause functional disability in varying severities and puts a multifaceted financial burden on individuals, society, and states.
- Trial name
- NCT05177341
- Testing
- Determining Preferred Walking Speed
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Trakya University
Lower Limb; Fusion, Congenital, Lower Limb Fracture
Investigating Auto Adjusting Dynamic AFO
Offloading Ankle Foot Orthoses (AFOs) are devices designed for people following lower-limb reconstruction to restore mobility by reducing mechanical loading through the injury site and redistributing it proximally.
- Conditions
- Lower Limb; Fusion, Congenital, Lower Limb Fracture, Ankle Foot Injury
- Trial name
- NCT04623853
- Testing
- Variable Stiffness AFO
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Washington
Robot-aided Arm Therapy, Brain Injury, Motor Relearning Programme, Activities of Daily Living
Robot-Aided Neurorehabilitation of the Upper Extremities
Task-oriented repetitive movement can improve movement performance in patients with neurological or orthopedic lesions. The application of robotics can serve to assist, enhance, evaluate, and document neurological and orthopedic…
- Trial name
- NCT02434237
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Fracture, Lengthening; Leg
Pediatric Orthopaedic Implant Safety & Efficacy
Implant devices are important tools - their use is essential across a number of orthopaedic indications, including hip conditions, trauma and limb deformity.
- Conditions
- Fracture, Lengthening; Leg, Orthopedic Disorder, Deformity of Limb
- Trial name
- Global POISE (NCT05361980)
- Testing
- Pediatric orthopaedic implant
- Where
- Canada
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Neuropathy;Peripheral, Limb Ischemia
Feasibility and Clinical Utility of Paired Non-Invasive Hemodynamic and Tissue Oximetry Monitoring to Detect Limb Ischemia in Lithotomy-Positioned Surgeries
The LIMB Study is a prospective, observational pilot study evaluating the feasibility of combined non-invasive hemodynamic and lower-limb tissue oximetry monitoring during prolonged minimally invasive pelvic surgeries performed…
- Trial name
- LIMB (NCT07387653)
- Testing
- Lower-Extremity Perfusion Monitoring
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Amputation, Amputation, Traumatic
GaMA Metric to Quantify Functional Importance of Various Upper Limb Prosthetic Devices
The goal of this study is to utilize the Gaze and Movement Assessment (GaMA) metric to assess the effect of different prosthetic components on compensatory movements used to complete activities of daily living.
- Conditions
- Amputation, Amputation, Traumatic, Amputation; Traumatic, Hand, Amputation; Traumatic, Limb
- Trial name
- NCT06420687
- Testing
- Clinically prescribed prosthesis, Experimental prosthesis - Wrist rotation + 1-DOF, Experimental prosthesis - Wrist rotation + Wrist flexion +1-DOF
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab