Clinical trials: Extremity Injury
Hand Injuries/Disease Requiring Surgery to the Hand
A Study Investigating Ways to Make Local Anaesthetic Hand Surgery Less Painful - Reducing Tourniquet Associated Pain
Hand surgery requires a reduced blood flow to the hand during the operation, which is achieved using a tourniquet (tightly inflated circumferential cuff) around the upper arm. However this tourniquet is painful.
- Trial name
- ReTAP (NCT01611064)
- Testing
- Oxygen, Medical air
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Chronic Pain, Low Back Pain
Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain
The purpose of this study is to investigate, in two phases: (1) the feasibility and safety of Virtual Embodiment Therapy in treating chronic pain of lower back and upper limbs and (2) the efficacy of Virtual Embodiment Therapy on…
- Conditions
- Chronic Pain, Low Back Pain, Fibromyalgia, Upper Extremity Dysfunction
- Trial name
- NCT04060875
- Testing
- Karuna Labs Virtual Reality Software
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Karuna Labs Inc.
Pediatric Extremity Fracture, Pediatric Extremity Soft Tissue Injury
Peripheral Nerve Blocks in Pediatric Orthopedic Patients
Context: Single shot peripheral nerve blocks have limited duration of action depending on the local anesthetic agent used in the block. But it rarely lasts longer than 12 hrs.
- Trial name
- NCT02236130
- Testing
- Regional block, General Anesthesia, Local Anesthetic Ropivacaine
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Spinal Cord Injuries
Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury
Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with…
- Trial name
- NCT02323945
- Testing
- AIH, Walk, Strength
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Knee Injuries, Anterior Cruciate Ligament Injuries
Effect of Neuromuscular Warm-up on Injuries in Female Athletes
The goal of the study is to determine effect of coach-led neuromuscular warm-up on non-contact, lower extremity (LE) injury rates among female athletes in a predominantly non-white public high school system.
- Conditions
- Knee Injuries, Anterior Cruciate Ligament Injuries, Ankle Injuries, Lower Extremity Injuries
- Trial name
- NCT01092286
- Testing
- neuromuscular warm-up
- Where
- United States
- Volunteers
- 1,653 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Spinal Cord Injuries, Cerebral Palsy
LEAP a New Overground Body Weight Support Robot: Usability Trial
People with central nervous system disorders such as spinal cord injury, stroke, cerebral palsy, Parkinson's disease, multiple sclerosis, etc… often have impaired lower extremity function that limits activities of daily life and…
- Conditions
- Spinal Cord Injuries, Cerebral Palsy, Parkinson Disease, Multiple Sclerosis
- Trial name
- LEAP (NCT03458169)
- Testing
- Therapist LEAP session feedback, Participant LEAP session feedback, LEAP risk control validation
- Where
- Switzerland
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Clinique Romande de Readaptation
Sports Injury Risk, Lower Extremity Injuries
Association Between Pre-Season Physical Capacity and Injury Risk in Professional Soccer Players
This prospective observational study aims to investigate the relationship between pre-season physical capacities and lower-extremity injury risk during the competitive season in professional male soccer players.
- Conditions
- Sports Injury Risk, Lower Extremity Injuries, Physical Fitness
- Trial name
- NCT07868276
- Testing
- Pre-Season Physical Performance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Fatigue, Muscle Injury
Immediate and Short-term Effects of Low-level Laser
Athletes experience an exhaustive routine of training, associated with the reduced time of rest, facilitates the appearance of muscle fatigue, which increases the risk of muscle injuries, especially during the execution of the…
- Trial name
- NCT05344183
- Testing
- Low-level laser
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Amapá
Surgical Wound, Wound Heal
Evaluating the Outcomes for Incisional Application of Negative Pressure for Nontraumatic Amputations
The purpose of this study is to evaluate how well subjects heal after surgery who receive standard dressings or incisional negative pressure wound therapy for non-traumatic amputation sites.
- Conditions
- Surgical Wound, Wound Heal, Amputation
- Trial name
- NCT03250442
- Testing
- PrevenaTM Device, Standard Dry Dressing
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Postural Stability, Dynamic Knee Valgus
The Effect Subtalar Joint Pronation on Postural Stability and Lower Extremity Alignment
The lower extremity consists of sequent columns. The deviation of one segment from its normal alignment in the lower extremity also affects the alignment of the other segments.
- Conditions
- Postural Stability, Dynamic Knee Valgus, Injury Prevention
- Trial name
- NCT05606835
- Testing
- Postural stability assessment, Frontal plan prjection angle, Foot and Ankle Ability Measure
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Lower Extremity Problem, Musculoskeletal Injury
Adolescent Normative Sport Movement Analysis
The objective of this study is to collect baseline data from a normative population of adolescents who participate in organized "land-based" sports, that gender and age matches some of the population of patients expected to be…
- Trial name
- NCT05068544
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- MultiCare Health System Research Institute
Sports Injuries
Adaptation in Lower Extremity After 3 Running Days, With a Group Trained by Eccentric Overload
This study evaluates the changes in muscles and tendons in the lower limb after an intervention of fatigue during 3 consecutive days between trained or not healthy subjects.
- Trial name
- NCT02481063
- Testing
- Control, Eccentric Overload
- Where
- Spain
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidad San Jorge
Cervical Spinal Cord Injury
Combined Therapeutic Air Mixture and Electrical Stimulation to Improve Breathing and Hand Function in Spinal Cord Injury
The goal of this clinical trial is to determine whether people with paralysis due to a spinal cord injury can benefit from breathing short intermittent bouts of air with low oxygen (O2) combined with slightly higher levels of…
- Trial name
- AIHH+tSCS (NCT06101199)
- Testing
- Acute Intermittent Hypercapnic Hypoxia, Transcutaneous spinal cord stimulation
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Behavior, Amputation
Self-Management for Amputee Rehabilitation Using Technology.
Lower Limb Amputations (LLAs) are a substantial burden on the Canadian health services with nearly 50,000 cases reported between 2006 and 2011.
- Conditions
- Behavior, Amputation, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury)
- Trial name
- SMART (NCT04953364)
- Testing
- SMART, Control
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hemorrhage, Hypovolemic Shock
Efficacy of Prehospital Tourniquet Models for Arterial Occlusion in Upper and Lower Limbs
The goal of this clinical trial is to compare the occlusive capability and mechanical behavior of different commercially available pre-hospital tourniquet models and the results of their application on upper and lower limbs, in…
- Conditions
- Hemorrhage, Hypovolemic Shock, Tourniquets
- Trial name
- TQ-BR (NCT06725602)
- Testing
- TQ - Proximal Application ("high and tight"), TQ - Controlled application (2-3 inches)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Overuse Injuries, Musculoskeletal Make-up in the Lower Extremities
Knowledge of Predicting Increased Risk for an Overuse Injury in Runners
The purpose of this study is to examine the skeleton of the legs and the running style in order to predict a possible overuse injury.
- Trial name
- NCT01979562
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northern Orthopaedic Division, Denmark
Hand Injuries and Disorders, Anesthesia, Local
Evaluation of Second Esmarch Application on Intravenous Regional Anesthesia Effectiveness
Intravenous regional anesthesia is a commonly used technique in the outpatient setting for short hand and upper extremity cases, such as carpal tunnel release or trigger finger release.
- Conditions
- Hand Injuries and Disorders, Anesthesia, Local, Upper Extremity Injury
- Trial name
- NCT03702387
- Testing
- standard intravenous regional anesthesia (IVRA) with reapplication of esmach
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Amputation Wound, Traumatic Amputation of Toe
Longitudinal Study of Weight Change Following Lower Limb Amputation
The purpose of this study is to assess weight change in a population of Veterans with amputations. Little is known about the how weight changes following an amputation.
- Conditions
- Amputation Wound, Traumatic Amputation of Toe, Dysvascular Amputation of Lower Limb
- Trial name
- NCT00932399
- Where
- United States
- Volunteers
- 4,549 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Radius Fractures
Comparison 1 Plane-2 Injection and 2 Plane-2 Injection Ultrasound-guided Supraclavicular Brachial Plexus Block
The supraclavicular block can provide effective surgical anesthesia of the forearm and hand. There have been many different approaches to ultrasound-guided supraclavicular brachial plexus block (US-SCBPB) according to the needle…
- Trial name
- US-SCBPB (NCT02533557)
- Testing
- stimuplex insulated needle, lidocaine mixed with epinephrine
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gachon University Gil Medical Center
Groin Injury
Comparison of the Effect of Copenhagen Adduction Exercises Performed at Different Load-intensity
The aim of our study is to compare the effects of the Copenhagen adduction exercise, performed at different loading intensities, on hip muscle strength development, performance, flexibility, and delayed onset muscle soreness.
- Trial name
- NCT06104722
- Testing
- High-intensity Copenhagen adduction exercise, Low-intensity Copenhagen adduction exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University