Clinical trials: Extubation
Tachycardia, Hypertension
To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Saturation, With or Without Giving Reversal Agent on Extubation, in Patients Receiving Single Shot of Atracurium , and to Observe Post Operative Residual Paralysis and Airway Reflexes in PACU.
The goal of this clinical trial is to to observe the haemodynamic parameters including Heart Rate Blood pressure Respiratory rate and Oxygen Saturation with or without giving reversal agent on extubation in patients receiving…
- Conditions
- Tachycardia, Hypertension, Hypoxia, Hyperventilation
- Trial name
- NCT07097441
- Testing
- neostigmine (reversal agent)
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Stress
Effects of TEAS on Stress Response During Extubation of General Anesthesia in Elderly Patients
Elderly patients have an increased risk of stress responses during extubation after general anaesthesia for an elective supratentorial craniotomy.
- Trial name
- NCT02533388
- Testing
- Hwato Electronic Acupuncture Treatment Instrument
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Prone posıtıon
Extruded the effectıveness of Prone posıtıon ın ınfants evaluatıon
The aim of this study was to determine the effect of prone position on vital signs, arterial blood gases and blood values in 0-1 year old infants extubated after congenital heart surgery.
- Trial name
- NCT06493058
- Testing
- Prone positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Preterm Infant
Effects of Two Modalities of Non-invasive Ventilation After Extubation in Very Low Birth Weight Neonates
The objective of this study is to evaluate the effects of continuous positive airway pressure and nasal intermittent positive pressure ventilation on breathing pattern variables of very low birth weight neonates immediately after…
- Trial name
- NCT03551314
- Testing
- Nasal Intermittent Positive Pressure, Continuous Positive Airway Pressure
- Where
- 2 sites in Brazil
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Upper Respiratory Tract Infections
Evaluation of Extubation Criteria in Children With Upper Respiratory Infection (URI)
The investigators are currently completing a data collection to try to optimize pediatric patients' preoperative screening, in the setting of an upper respiratory infection.
- Trial name
- NCT04155892
- Where
- United States
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Pediatric Post Extubation Dysphagia
The Use of PEDI_ EAT 10 Score Versus Nurse Performed Screening in the Assessment of Post Extubation Dysphagia
Invasive mechanical ventilation is one of the most common interventions in critically ill patients, and is invariably characteristic, if not defining, of ICU therapeutic regimen Much attention has been paid to complications…
- Trial name
- NCT05828537
- Testing
- endotracheal tube
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Extubation Success, Extubation Failure
Combined RSBI, TOF, and BIS for Prediction of Extubation Success
This prospective observational study aims to evaluate the predictive value of the combined use of the rapid shallow breathing index, train-of-four ratio, and bispectral index for extubation success after general anesthesia.
- Conditions
- Extubation Success, Extubation Failure, Postoperative Respiratory Complications
- Trial name
- NCT07577453
- Testing
- Combined pre-extubation assessment using RSBI, TOF ratio, and BIS
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital
FESS Operation
Intratracheal Dexmedetomidine Versus Lidocaine for Smooth Tracheal Extubation
compare the efficacy of intratracheal dexmedetomidine versus intratracheal lidocaine in achieving smooth tracheal extubation in patients undergoing Functional Endoscopic Sinus surgery and reconstructive nasal surgeries under…
- Trial name
- NCT07504497
- Testing
- dexmedetomidine Lidocaine Saline
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Younes Ahmed Younes
Measure Time to First Rescue Analgesia Following Extubation
Opioid Free Anesthesia in Shoulder Arthroscope
The investigators will assess opioid free anesthesia technique as regards effectiveness \& duration of post operative analgesia in shoulder arthroscpe surgeries
- Trial name
- NCT06834854
- Testing
- fentanyl, Lidocaine (drug)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Respiratory Distress Syndrome (RDS), PreTerm Neonate
Breathing Patterns in Infants Before and After Extubation
The primary objective of this study is to compare work of breathing indices before and after extubation in intubated premature infants admitted to the Christiana Care Neonatal Intensive Care Unit.
- Trial name
- NCT07542301
- Testing
- Observation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Airway Complications
Optimal End-Tidal (ET) Sevoflurane and Desflurane Concentration for Extubation of Supreme Laryngeal Mask Airway (LMA) in Adults
The purpose of this study is to determine the optimal volatile anaesthetic (sevoflurane and desflurane) to remove a Supreme LMA in adults in which there is minimal airway response.
- Trial name
- NCT01083953
- Testing
- Sevoflurane, Desflurane
- Where
- Malaysia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Anesthesia, Anesthesia; Adverse Effect
Dexamethasone vs Bicarbonate to Intracuff Lignocaine 2% in General Anaesthesia
This study is designed to evaluate and compare the effect on hemodynamics, extubation response and patients satisfaction score in patients with ETT cuff filled with either mixture of lignocaine with sodium bicarbonate or with a…
- Conditions
- Anesthesia, Anesthesia; Adverse Effect, Anesthesia Intubation Complication
- Trial name
- NCT03833947
- Testing
- lignocaine+bicarbonate, lignocaine+dexamethasone
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aligarh Muslim University
Beta Blocker, Hemodynamic Instability
The Effects of Esmolol on the Hemodynamic Response to Orotracheal Extubation
Beta-blockers are useful tools for the prevention of hemodynamic instability in the manipulation of airways. The main objective of the present study is to evaluate the effectiveness of using esmolol in attenuating hemodynamic…
- Trial name
- NCT04264286
- Testing
- Prophylactic esmolol
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital de Base
Cough
Does Precise Delivery of Remifentanil Decrease Coughing at Emergence From Anesthesia
The investigators want to find a way to reduce or stop patients from coughing at the end of surgery when the breathing tube is taken out.
- Trial name
- NCT03783676
- Testing
- Remifentanil, Normal saline
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Vermont Medical Center
Myasthenia Gravis Associated With Thymoma
Early Versus Late Extubation in Myasthenia Gravis Patients
MYASTHENIA GRAVIS (MG) is an autoimmune disease characterized by varying degrees of muscle weakness and fatigability worsened with exertion and relieved with rest。Thymectomy plays an important role in the management of these…
- Trial name
- NCT03468452
- Testing
- extubation
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Nausea, Vomiting
The Effect on Thirst, Nausea-Vomiting and Comfort Levels of Menthol Lozenge Applied After Extubation
It is reported that approximately 17.5 million people die worldwide each year due to cardiovascular diseases, including ischemic heart disease, cerebrovascular disease and rheumatic heart disease.
- Conditions
- Nausea, Vomiting, Thirst
- Trial name
- NCT04994262
- Testing
- Menthol Lozenge
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Coughing Responses at Tracheal Extubation, Breathing Patterns
Endotracheal Tube Intolerance and Respiratory Airflow Perception
This is a case-control study designed to enroll 224 patients who will undergo tracheal intubation for general anesthesia in the operating rooms of Peking University People's Hospital between July 20, 2026, and October 31, 2026.
- Trial name
- NCT07759284
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Airway Complication of Anesthesia, Respiratory Complications of Care
Comparison of Deep Versus Awake Tracheal Extubation in Adults
Prospective, randomized, single-blinded controlled study to compare the airway and respiratory complications of deep and awake tracheal extubations in adults.
- Trial name
- CDATE (NCT05361850)
- Testing
- Extubation
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- United States Navy
Anesthesia Complication
Perioperative Complications of Deep Extubation in Adults
The investigators propose a prospective observational cohort study in order to investigate the perioperative respiratory complications of deep extubation in adults undergoing eye and head-and-neck surgery at Massachusetts Eye and…
- Trial name
- NCT04557683
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Anesthesia Airway Management, Respiratory Complications
Deflated and Inflated Cuff Endotracheal Extubations
General anesthesia is a treatment with medicine to make a patient unconscious for surgery. This is sometimes called "being put to sleep" or "being put under." Most of the time, a breathing tube is used to help a machine breathe…
- Trial name
- DICEE (NCT06990308)
- Testing
- Inflated Cuff Extubation, Deflated Cuff Extubation
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Naval Medical Center Camp Lejeune