Clinical trials: Eye
No Eye Disease
Optical Coherence Tomography (OCT) Data Collection Study
Collect OCT data to evaluate the range and age trend of eye measurements.
- Trial name
- NCT01459731
- Where
- 5 sites in United States, United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Optovue
Uveitis
A Study of Efficacy and Safety of GenSci048 in Subjects With Active Uveitis.
This study is designed to evaluate the efficacy and safety of GenSci048 compared with placebo in subjects with active non-infectious uveitis.
- Trial name
- NCT07547995
- Testing
- GenSci048
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Presbyopia
Clinical Assessment of a Multifocal Contact Lens for People Who Use Reading Glasses Only
The purpose of this trial is to evaluate the use of multifocal contact lenses in people who use reading glasses only.
- Trial name
- NCT01268501
- Testing
- Lotrafilcon B multifocal contact lens
- Volunteers
- 103 people
- Sponsor
- CIBA VISION
Blepharitis
The Effects of Azithromycin Ophthalmic Solution, 1% Versus Placebo in Subjects With Blepharitis During a Four-Week Treatment Period (P08638)
The objective of this study is to compare the safety and efficacy of azithromycin ophthalmic solution, 1% versus placebo over a four-week treatment period.
- Trial name
- NCT00894530
- Testing
- Azithromycin ophthalmic solution, 1%
- Where
- 26 sites in United States
- Volunteers
- 314 people
- Sponsor
- Merck Sharp & Dohme LLC
Dry Eye
An Evaluation of the Daytime Use of an Investigational Lubricant Eye Drop
The purpose of this study is to describe the subjective assessments of an investigational lubricant eye drop.
- Trial name
- NCT01139372
- Testing
- FID 115958D (Lubricant Eye Drop)
- Volunteers
- 96 people
- Sponsor
- Alcon Research
Allergic Conjunctivitis
A Multi-Center Study Evaluating the Onset and Duration of Action of AC-170 0.24% Compared to Vehicle in the Conjunctival Allergen Challenge (CAC)
The purpose of this study is to evaluate the onset and duration of action of AC-170 0.24% compared to vehicle in the prevention of the signs and symptoms of allergic conjunctivitis in the conjunctival allergen challenge (CAC)…
- Trial name
- NCT01551056
- Testing
- AC-170 0.24%, AC-170 0%
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Aciex Therapeutics, Inc.
Meibomian Gland Dysfunction, Blepharitis
Pilot Study Comparing the Safety and Efficacy of Two Dosing Regimens of TP-03 for the Treatment of MGD
The purpose of this study is to compare the safety and efficacy of TP-03, 0.25%, an eyedrop, BID vs TID dosing regimens for the treatment of meibomian gland dysfunction in patients with Demodex lid infestation.
- Conditions
- Meibomian Gland Dysfunction, Blepharitis, Demodex Infestation
- Trial name
- Ersa (NCT05454956)
- Testing
- TP-03, TP-03 Vehicle
- Where
- 5 sites in United States
- Volunteers
- 39 people
- Sponsor
- Tarsus Pharmaceuticals, Inc.
Myopia
Refitting Somofilcon A Sphere Contact Lens Wearers Into Fanfilcon A Sphere Lenses for 4-Weeks of Wear
The aim of this subject-masked prospective study is to evaluate the clinical performance of habitual wearers of Clariti Elite sphere lenses after a refit with Avaira Vitality sphere lenses.
- Trial name
- NCT03974802
- Testing
- somofilcon A contact lens, fanfilcon A contact lens
- Where
- Mexico
- Volunteers
- 41 people
- Sponsor
- CooperVision, Inc.
Diabetic Retinopathy
Evaluation of RC28-E Injection in Diabetic Retinopathy
This is a randomized, open-label, multicenter study of the efficacy and safety of RC28-E injection (a chimric decoy receptor trap fusion protein by dual blockage of VEGF and FGF-2) in the treatment of patients with moderately…
- Trial name
- NCT04782128
- Testing
- RC28-E injection
- Where
- China
- Volunteers
- 120 people
- Sponsor
- RemeGen Co., Ltd.
Cataract
Study of the Femtosecond Laser System as Compared to Continuous Curvilinear Capsulorhexis for Cataract Surgery
The purpose of this study is to evaluate the safety and efficacy of the OptiMedica Femtosecond Laser System to perform surgical maneuvers used in the treatment of subjects with cataracts.
- Trial name
- NCT01069172
- Testing
- FS Laser Surgery, CCC Surgery
- Where
- Dominican Republic
- Volunteers
- 30 people
- Sponsor
- Abbott Medical Optics
Open-angle Glaucoma, Ocular Hypertension
IOP Lowering Efficacy of Travoprost/Brinzolamide Fixed Combination Ophthalmic Suspension in Patients With Open-Angle Glaucoma or Ocular Hypertension
The purpose of this study is to compare the safety and IOP-lowering efficacy of a fixed combination of Travoprost/Brinzolamide Ophthalmuc Suspension dosed BID and QD, to TRAVATAN dosed QD and a Vehicle dosed BID in patients with…
- Trial name
- NCT00527501
- Testing
- Travoprost/brinzolamide
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Alcon Research
Cataract
A Comparison of Visual Function After Bilateral Implantation of Presbyopia-correcting Intraocular Lenses (IOLs)
The purpose of this study is to prospectively evaluate postoperative visual and refractive parameters in a series of subjects bilaterally implanted with the AcrySof® IQ ReSTOR® +3 versus those bilaterally implanted with the…
- Trial name
- NCT01166971
- Testing
- ReSTOR +3, Tecnis MF
- Where
- 3 sites in United States
- Volunteers
- 65 people
- Sponsor
- Alcon Research
Rhinitis, Allergic, Perennial
ATAREAL (Antihistamine Treatment for Allergic Rhinitis in Real Life)
Comparison of clinical efficacy and safety of levocetirizine in PER continuous versus on demand, measured by evolution of individual symptom scores during 6 months.
- Trial name
- NCT00160680
- Testing
- Levocetirizine
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- UCB S.A. - Pharma Sector
Disorders of the Eye Following Cataract Surgery
Microbiological Evaluation of the Ocular Flora Before Cataract Surgery
The purpose of the present study is to elucidate the spectrum of ocular flora and their antimicrobial susceptibility profiles in patients undergoing routine cataract surgery.
- Trial name
- NCT02124603
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- SIFI SpA
Open Angle Glaucoma, Ocular Hypertension
DE-111 Against Timolol Ophthalmic Solution 0.5%
DE-111 ophthalmic solution will be evaluated for superiority in comparison with Timolol ophthalmic solution 0.5%, in IOP(intraocular pressure ) -lowering effect in primary open-angle glaucoma or ocular hypertension patients, in a…
- Trial name
- NCT01342094
- Testing
- DE-111 ophthalmic solution, Timolol ophthalmic solution 0.5%
- Where
- Japan
- Volunteers
- 166 people
- Sponsor
- Santen Pharmaceutical Co., Ltd.
Glaucoma, Glaucoma, Open-Angle
AqueSys Microfistula Implant in Refractory Glaucoma
To establish the safety and performance of the AqueSys Microfistula Implant in eyes with refractory glaucoma.
- Trial name
- NCT01640756
- Testing
- AqueSys Microfistula Implant
- Where
- 14 sites in United States
- Volunteers
- 60 people
- Sponsor
- AqueSys, Inc.
Endophthalmitis
Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery
Intracameral injection of 0.1% moxifloxacin solution after cataract surgery to prevent endophthalmitis
- Trial name
- NCT03244072
- Testing
- Moxifloxacin
- Where
- United States
- Volunteers
- 60,000 people, healthy volunteers welcome
- Sponsor
- Jason Ahee, M.D.
Uveitis, Posterior, Uveitis, Intermediate
A Study of LX211 in Clinically Quiescent Non-infectious Intermediate, Anterior and Intermediate, Posterior or Pan-Uveitis
The objective of this study is to evaluate the safety and efficacy of LX211 as therapy in subjects with clinically quiescent non-infectious uveitis
- Conditions
- Uveitis, Posterior, Uveitis, Intermediate, Panuveitis
- Trial name
- LUMINATE (NCT00404742)
- Testing
- LX211
- Where
- 41 sites in United States, Austria and 5 more
- Volunteers
- 232 people
- Sponsor
- Lux Biosciences, Inc.
Eye Disease
iCam Clinical Validation Study
Comparison study to assess photo image quality of a new color fundus camera compared to that of a commercially available color fundus camera.
- Trial name
- NCT01600261
- Where
- 2 sites in United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Optovue
Macular Degeneration
Clinical Study Of EYE001 For Wet-Type AMD (Age-Related Macular Degeneration)
This study will examine the efficacy and safety of pegaptanib sodium in Japanese patients with wet-type AMD, in order to establish that there is no large difference in the efficacy and the safety of the drug between Western and…
- Trial name
- NCT00150202
- Testing
- pegaptanib sodium
- Where
- 14 sites in Japan
- Volunteers
- 90 people
- Sponsor
- Pfizer
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