Clinical trials: Eye
Ophthalmology, Macular Degeneration
A Follow-up Physician Survey to Evaluate Physician Knowledge of Safety and Safe Use Information for Aflibercept Administered by Intravitreal Injection in Europe
With this follow up physician survey researcher want to collect the same data from all participants of the study using a highly structured questionnaire.
- Trial name
- NCT04067583
- Testing
- Physician questionnaire
- Where
- Germany
- Volunteers
- 454 people, healthy volunteers welcome
- Sponsor
- Bayer
Myopia
One Month Performance Comparison Between Two Commercially Available Silicone Hydrogel Lenses
The purpose of this study is to compare the performance of two commercially marketed contact lenses when worn for up to one month in a daily wear modality.
- Trial name
- NCT01300741
- Testing
- Lotrafilcon B contact lens (AIR OPTIX® AQUA), Galyfilcon A contact lens (ACUVUE® ADVANCE® Plus), Contact lens solution (Clear Care®)
- Volunteers
- 75 people
- Sponsor
- CIBA VISION
Retinopathy of Prematurity (ROP)
Extension Study to Evaluate the Long-term Outcomes of Subjects in Study 20090
This is a follow-up study to evaluate the long term outcome of babies treated in the FIREFLEYE study.
- Trial name
- FIREFLEYE next (NCT04015180)
- Testing
- Eylea (Aflibercept, BAY86-5321), Laser photocoagulation
- Where
- 55 sites in Argentina, Belgium and 22 more
- Volunteers
- 100 people
- Sponsor
- Bayer
Myopia
A Product Performance Evaluation of a Novel Contact Lens for Daily Disposable Use
Evaluation of the clinical performance of a novel Bausch \& Lomb daily disposable contact lens when compared to the currently marketed Bausch \& Lomb SofLens® daily disposable contact lenses and the currently marketed Johnson and…
- Trial name
- NCT00784641
- Testing
- Novel Bausch & Lomb daily disposable contact lenses, Bausch & Lomb SofLens daily disposable contact lenses., Johnson and Johnson 1-Day Acuvue Moist contact lenses
- Where
- United States
- Volunteers
- 567 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Diabetic Retinopathy
A Study of PER-001 in Participants With Diabetic Retinopathy
This is a Phase 2a, randomized, single-masked (participant), sham controlled clinical study.
- Trial name
- NCT06003751
- Testing
- PER-001 Intravitreal Implant - Low Dose, PER-001 Intravitreal Implant - High Dose
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Perfuse Therapeutics, Inc.
Refractive Errors
Clinical Evaluation of Two Monthly Contact Lenses
The purpose of this study is to explore overall vision with BIOFINITY® ENERGYS™ contact lenses as compared to BIOFINITY® contact lenses after one week of wear.
- Trial name
- NCT03459131
- Testing
- Comfilcon A with Digital Zone Optics™ contact lenses, Comfilcon A contact lenses
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Alcon Research
Aphakia, Corneal Astigmatism
Clareon Toric Study (T2-T9)
The purpose of this post-market study is to describe the long-term safety and performance of Clareon Toric Intraocular Lenses (IOLs).
- Trial name
- NCT06285695
- Testing
- Clareon Toric IOL, Cataract surgery
- Where
- 6 sites in Canada
- Volunteers
- 129 people
- Sponsor
- Alcon Research
Dry Eye
Efficacy and Safety of a New Multi-dose Lubricant Eye Drop Concomitant With Restasis® (Cyclosporine A) for the Treatment of Dry Eye Symptoms
To evaluate the efficacy, safety and tolerability of a combination of Optive® Artificial Tears with Restasis®.The primary hypothesis is that the Ocular Surface Disease Index (OSDI) score and symptoms will be the same or lower…
- Trial name
- NCT00405457
- Testing
- Restasis, Optive Tears
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Innovative Medical
Dry Eye Syndrome
A Study of RX-10045 in the Treatment of Dry Eye Disease
The primary purpose of this study is to assess the efficacy, tolerability and safety of RX-10045 Ophthalmic Solution in patients with Dry Eye Disease.
- Trial name
- NCT01675570
- Testing
- RX-10045, Vehicle for RX-10045
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- C.T. Development America, Inc.
Concussion, Brain, Mild Traumatic Brain Injury
A Highly Portable Device for Assessment of Mild Traumatic Brain Injury in Deployed and Far-Forward Settings
The purpose of this study is to develop a highly portable, ruggedized diagnostic tool for concussion, EyeBOX Lens (EBLens), that can be utilized in deployed field and far-forward settings.
- Trial name
- NCT05527041
- Testing
- EyeBOX Lens (EBLens)
- Where
- United States
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Oculogica, Inc.
Uveitis; Posterior, Disorder
Study Assessing Double-masked Uveitis Treatment
The purpose of this study is to evaluate the safety and efficacy of intravitreal injections of DE-109 ophthalmic solution.
- Trial name
- SAKURA (NCT01358266)
- Testing
- DE-109 44 ug, DE-109 440 ug, DE-109 880 ug
- Where
- 151 sites in United States, Argentina and 15 more
- Volunteers
- 592 people
- Sponsor
- Santen Inc.
Refractive Error, Cataract
Vision Measured by the Vimetrics CVA Compared With Chart Testing Under Similar Luminance and Contrast Conditions
Purpose of The Study: The purpose of this study is the following: A)To gather age-related normative visual acuity data for the Vimetrics Central Vision Analyzer (CVA, Vimetrics, LLC, Media, Pa) B)To gather visual acuity data for…
- Conditions
- Refractive Error, Cataract, Maculopathy
- Trial name
- NCT02028351
- Where
- 2 sites in United States, Austria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sinclair Technologies, LLC
Myopia
Observational Survey Study on the Impact of Myopia and Its Complications on Quality of Life.
This study aims to assess the impact of myopia in childhood and its long-term complications in adulthood on health-related Quality of Life (HRQoL), providing valuable data for cost-effectiveness models.
- Trial name
- NCT06912802
- Testing
- Non-Intervention
- Where
- 10 sites in Denmark, France and 5 more
- Volunteers
- 344 people
- Sponsor
- Santen SAS
Migraine
Acute Treatment Trial in Adult Subjects With Migraines
The purpose of the study is to evaluate the safety and efficacy of three different intranasal dose levels of zavegepant (BHV-3500), relative to placebo, in the acute treatment of moderate to severe migraine.
- Trial name
- NCT03872453
- Testing
- Zavegepant, Intranasal Aptar Pharma Unit Dose System
- Where
- 82 sites in United States
- Volunteers
- 2,154 people
- Sponsor
- Pfizer
Primary Open Angle Glaucoma
CRISPR/Cas9 Instantaneous Gene Editing Therapy to Intraocular Hypertensive POAG With MYOC Mutation
This study is intented to evaluate the safety, tolerability and preliminary efficacy of CRISPR/Cas9 Instantaneous Gene Editing Therapy (BD113 virus-like particle, also BD113vLVP) in patients with primary open-angle glaucoma…
- Trial name
- NCT06465537
- Testing
- BD113vVLP
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Shanghai BDgene Co., Ltd.
Optical Biometry of the Human Eye, General Analysis of the Anterior Chamber of the Human Eye
Clinical Trial ES 900 - 2019
The primary objective of this clinical trial is to assess the clinical performance of the investigational device. To that end, the Limits of Agreement with respect to comparator devices are analyzed.
- Trial name
- NCT04112472
- Testing
- EYESTAR 900
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Haag-Streit AG
Ocular Hypertension, Open Angle Glaucoma
Safety and Efficacy Study of JV-GL1 in Patients With Open-Angle Glaucoma or Ocular Hypertension
The aim of this research study is to assess the safety and feasibility of lowering intraocular pressure (IOP) using an experimental study drug, JV-GL1.
- Trial name
- NCT04761705
- Testing
- JV-GL1, Latanoprost 0.005% Ophthalmic Solution
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- JeniVision, Inc.
Fabry Disease
Understanding Fabry Disease Therapy Choices Through the Eyes of the Patients
The objective of this study is to increase the understanding surrounding the choices presented to patients and families impacted by Fabry disease.
- Trial name
- NCT04804566
- Testing
- This is a non-interventional study
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Amicus Therapeutics
Cataracts
Evaluation of Real-World Data on the Performance of the TECNIS Odyssey™ IOL
Retrospective collection of data from medical records, multicenter, post-market clinical follow-up study.
- Trial name
- NCT05991960
- Testing
- Intervention
- Where
- 12 sites in United States
- Volunteers
- 96 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Dry Eye Syndrome
Study to Evaluate the Efficacy and Safety of CKD-350
The purpose of this study is to compare the efficacy and safety of CKD-350 in patients with dry eye syndrome
- Trial name
- NCT02777723
- Testing
- Xenobella, Isotonic 0.3% Sodium Hyaluronate
- Where
- 14 sites in South Korea
- Volunteers
- 138 people
- Sponsor
- Chong Kun Dang Pharmaceutical
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